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Murcko scaffold

2-(5-Phenyl-1,2,4-oxadiazol-3-yl)pyridine scaffold

88 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
88
With full pages
15
Scaffold SMILES

c1ccc(-c2nc(-c3ccccn3)no2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(5-Phenyl-1,2,4-oxadiazol-3-yl)pyridine page
Murcko scaffold c1ccc(-c2nc(-c3ccccn3)no2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 88 chemicals

2-[5-(3-Chlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C13H8ClN3O, CAS 327056-08-6
2-[5-(3-Chlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 327056-08-6C13H8ClN3O
5-(2-Chloro-5-nitrophenyl)-3-(pyridin-2-yl)-1,2,4-oxadiazole chemical structure, C13H7ClN4O3, CAS 432018-14-9
5-(2-Chloro-5-nitrophenyl)-3-(pyridin-2-yl)-1,2,4-oxadiazole
CAS 432018-14-9C13H7ClN4O3
2-[5-(3,4-Dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C13H7Cl2N3O, CAS 432016-70-1
2-[5-(3,4-Dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 432016-70-1C13H7Cl2N3O
5-(4-Methyl-3-nitrophenyl)-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C14H10N4O3, CAS 380579-08-8
5-(4-Methyl-3-nitrophenyl)-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 380579-08-8C14H10N4O3
2-[5-(2,4-Dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C13H7Cl2N3O, CAS 339103-05-8
2-[5-(2,4-Dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 339103-05-8C13H7Cl2N3O
5-(3-Bromophenyl)-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C13H8BrN3O, CAS 327056-52-0
5-(3-Bromophenyl)-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 327056-52-0C13H8BrN3O
2-[5-(4-Bromophenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C13H8BrN3O, CAS 370853-73-9
2-[5-(4-Bromophenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 370853-73-9C13H8BrN3O
2-[5-(2-Chloro-4-methylphenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C14H10ClN3O, CAS 430459-69-1
2-[5-(2-Chloro-4-methylphenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 430459-69-1C14H10ClN3O
2-[5-(3,4,5-Trimethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C16H15N3O4, CAS 443328-18-5
2-[5-(3,4,5-Trimethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 443328-18-5C16H15N3O4
2-[5-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C15H13N3O3, CAS 425397-55-3
2-[5-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 425397-55-3C15H13N3O3
2-[5-(2-Bromophenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C13H8BrN3O, CAS 587001-82-9
2-[5-(2-Bromophenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 587001-82-9C13H8BrN3O
2-[5-(4-Chlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C13H8ClN3O, CAS 404863-43-0
2-[5-(4-Chlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 404863-43-0C13H8ClN3O
2-[5-(2-Chlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C13H8ClN3O, CAS 27199-42-4
2-[5-(2-Chlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 27199-42-4C13H8ClN3O
2-(5-Phenyl-1,2,4-oxadiazol-3-yl)pyridine chemical structure, C13H9N3O, CAS 13389-61-2
2-(5-Phenyl-1,2,4-oxadiazol-3-yl)pyridine
CAS 13389-61-2C13H9N3O
2-[5-(3-Methoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-pyridine chemical structure, C14H11N3O2, CAS 327056-09-7
2-[5-(3-Methoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-pyridine
CAS 327056-09-7C14H11N3O2
5-(4-Methoxyphenyl)-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C14H11N3O2, CAS 419552-59-3
5-(4-Methoxyphenyl)-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 419552-59-3C14H11N3O2
2-[5-(4-tert-Butylphenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C17H17N3O, CAS 331959-89-8
2-[5-(4-tert-Butylphenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 331959-89-8C17H17N3O
3-(2-Pyridyl)-5-(3,5-dimethoxyphenyl)-1,2,4-oxadiazole chemical structure, C15H13N3O3, CAS 327056-19-9
3-(2-Pyridyl)-5-(3,5-dimethoxyphenyl)-1,2,4-oxadiazole
CAS 327056-19-9C15H13N3O3
5-(3-Nitrophenyl)-3-(2-pyridyl)-1,2,4-oxadiazole chemical structure, C13H8N4O3, CAS 5799-85-9
5-(3-Nitrophenyl)-3-(2-pyridyl)-1,2,4-oxadiazole
CAS 5799-85-9C13H8N4O3
5-(4-Nitrophenyl)-3-(2-pyridyl)-1,2,4-oxadiazole chemical structure, C13H8N4O3, CAS 381713-06-0
5-(4-Nitrophenyl)-3-(2-pyridyl)-1,2,4-oxadiazole
CAS 381713-06-0C13H8N4O3
2-[5-(3-Iodophenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C13H8IN3O, CAS 425610-91-9
2-[5-(3-Iodophenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 425610-91-9C13H8IN3O
2-[5-(4-Iodophenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C13H8IN3O, CAS 381698-98-2
2-[5-(4-Iodophenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 381698-98-2C13H8IN3O
2-[5-(3,4-Dimethylphenyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C15H13N3O, CAS 690987-63-4
2-[5-(3,4-Dimethylphenyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 690987-63-4C15H13N3O
5-(2-Fluorophenyl)-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C13H8FN3O, CAS 693235-68-6
5-(2-Fluorophenyl)-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 693235-68-6C13H8FN3O