Murcko scaffold

Ring system with 4 rings and 23 atoms

94 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 23
Chemicals: 94
With full pages: 2

Scaffold SMILES

O=C(Nc1ccccc1)c1cc2c(=O)n3ccccc3nc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1ccccc1)c1cc2c(=O)n3ccccc3nc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 94 chemicals

1,9-Dimethyl-4-oxo-N-(m-tolyl)-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 724738-32-3C₂₀H₁₈N₄O₂

1,9-Dimethyl-4-oxo-N-phenyl-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 724739-62-2C₁₉H₁₆N₄O₂

1,9-Dimethyl-4-oxo-N-(o-tolyl)-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 724739-66-6C₂₀H₁₈N₄O₂

N-Ethyl-1,9-dimethyl-N-(3-methylphenyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 724738-35-6C₂₂H₂₂N₄O₂

N-(3,5-Dimethylphenyl)-1,9-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 724739-58-6C₂₁H₂₀N₄O₂

1,7-Dimethyl-4-oxo-N-(3-(trifluoromethyl)phenyl)-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 896809-84-0C₂₀H₁₅F₃N₄O₂

N-(3-Chloro-4-fluorophenyl)-1,9-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 896824-92-3C₁₉H₁₄ClFN₄O₂

N-(3-Methoxyphenyl)-1,7-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 896831-36-0C₂₀H₁₈N₄O₃

N-(4-Chlorophenyl)-1,7-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 896835-14-6C₁₉H₁₅ClN₄O₂

N-(3-Chloro-4-fluorophenyl)-1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 899388-24-0C₁₈H₁₂ClFN₄O₂

N-(4-Methoxy-3-nitrophenyl)-1,9-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 899404-63-8C₂₀H₁₇N₅O₅

$N,6-dimethyl-2-oxo-N-phenyl-1,6,8-triazatricyclo[7.4.0.0^{3,7}]trideca-3(7),4,8,10,12-pentaene-5-carboxamide chemical structure, C19H16N4O2, CAS 864853-72-5$

N,6-dimethyl-2-oxo-N-phenyl-1,6,8-triazatricyclo[7.4.0.0^{3,7}]trideca-3(7),4,8,10,12-pentaene-5-carboxamide

CAS 864853-72-5C₁₉H₁₆N₄O₂

$6-Methyl-2-oxo-N-phenyl-1,6,8-triazatricyclo[7.4.0.0^{3,7}]trideca-3(7),4,8,10,12-pentaene-5-carboxamide chemical structure, C18H14N4O2, CAS 864853-79-2$

6-Methyl-2-oxo-N-phenyl-1,6,8-triazatricyclo[7.4.0.0^{3,7}]trideca-3(7),4,8,10,12-pentaene-5-carboxamide

CAS 864853-79-2C₁₈H₁₄N₄O₂

1-Methyl-N-(4-methylphenyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 864853-82-7C₁₉H₁₆N₄O₂

N-(4-Ethylphenyl)-1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 864853-84-9C₂₀H₁₈N₄O₂

N-(4-Butylphenyl)-1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 864853-86-1C₂₂H₂₂N₄O₂

N-(3-Chlorophenyl)-1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 864853-91-8C₁₈H₁₃ClN₄O₂

N-(4-Chlorophenyl)-1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 864853-92-9C₁₈H₁₃ClN₄O₂

N-(3-Bromophenyl)-1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 864853-93-0C₁₈H₁₃BrN₄O₂

N-(4-Bromophenyl)-1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 864853-94-1C₁₈H₁₃BrN₄O₂

1-Methyl-4-oxo-N-(4-(trifluoromethyl)phenyl)-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide

CAS 864853-96-3C₁₉H₁₃F₃N₄O₂

$N-(3-Methoxyphenyl)-6-methyl-2-oxo-1,6,8-triazatricyclo[7.4.0.0^{3,7}]trideca-3(7),4,8,10,12-pentaene-5-carboxamide chemical structure, C19H16N4O3, CAS 864853-98-5$