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Murcko scaffold

2-Phenyl-N-(1,3,4-thiadiazol-2-yl)acetamide scaffold

112 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
112
With full pages
24
Scaffold SMILES

O=C(Cc1ccccc1)Nc1nncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-N-(1,3,4-thiadiazol-2-yl)acetamide page
Murcko scaffold O=C(Cc1ccccc1)Nc1nncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 112 chemicals

[2-Oxo-1-phenyl-2-(1,3,4-thiadiazol-2-ylamino)ethyl] acetate chemical structure, C12H11N3O3S, CAS 3610-63-7
[2-Oxo-1-phenyl-2-(1,3,4-thiadiazol-2-ylamino)ethyl] acetate
CAS 3610-63-7C12H11N3O3S
N-[5-(2-Methoxyethyl)-1,3,4-thiadiazol-2-yl]-2-phenylacetamide chemical structure, C13H15N3O2S, CAS 5551-57-5
N-[5-(2-Methoxyethyl)-1,3,4-thiadiazol-2-yl]-2-phenylacetamide
CAS 5551-57-5C13H15N3O2S
2-(4-Bromophenyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C11H10BrN3OS, CAS 349536-88-5
2-(4-Bromophenyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 349536-88-5C11H10BrN3OS
2-(4-Methoxyphenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C12H10F3N3O2S, CAS 312496-19-8
2-(4-Methoxyphenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 312496-19-8C12H10F3N3O2S
2-(3,4-Dimethoxyphenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C13H12F3N3O3S, CAS 636993-83-4
2-(3,4-Dimethoxyphenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 636993-83-4C13H12F3N3O3S
N-[5-(2-Methylpropyl)-1,3,4-thiadiazol-2-yl]-2-(4-nitrophenyl)acetamide chemical structure, C14H16N4O3S, CAS 510736-10-4
N-[5-(2-Methylpropyl)-1,3,4-thiadiazol-2-yl]-2-(4-nitrophenyl)acetamide
CAS 510736-10-4C14H16N4O3S
2-(4-Chlorophenyl)-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C14H16ClN3OS, CAS 519170-79-7
2-(4-Chlorophenyl)-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 519170-79-7C14H16ClN3OS
2-(4-Fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C11H7F4N3OS, CAS 521295-16-9
2-(4-Fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 521295-16-9C11H7F4N3OS
2-(4-Fluorophenyl)-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C14H16FN3OS, CAS 510737-20-9
2-(4-Fluorophenyl)-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 510737-20-9C14H16FN3OS
2-(4-Chlorophenyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C12H12ClN3OS, CAS 361183-42-8
2-(4-Chlorophenyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 361183-42-8C12H12ClN3OS
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-phenylacetamide chemical structure, C12H13N3OS, CAS 313251-98-8
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-phenylacetamide
CAS 313251-98-8C12H13N3OS
Ethyl 2-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]acetate chemical structure, C14H15N3O3S, CAS 313965-05-8
Ethyl 2-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]acetate
CAS 313965-05-8C14H15N3O3S
2-(4-Fluorophenyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C11H10FN3OS, CAS 432529-08-3
2-(4-Fluorophenyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 432529-08-3C11H10FN3OS
2-Phenyl-N-(1,3,4-thiadiazol-2-yl)acetamide chemical structure, C10H9N3OS, CAS 84954-79-0
2-Phenyl-N-(1,3,4-thiadiazol-2-yl)acetamide
CAS 84954-79-0C10H9N3OS
N-[5-(Ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-2-(4-methoxyphenyl)acetamide chemical structure, C13H15N3O2S2, CAS 311777-47-6
N-[5-(Ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-2-(4-methoxyphenyl)acetamide
CAS 311777-47-6C13H15N3O2S2
N-[5-(Ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-2-phenylacetamide chemical structure, C12H13N3OS2, CAS 392239-47-3
N-[5-(Ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-2-phenylacetamide
CAS 392239-47-3C12H13N3OS2
2-(2-Chloro-6-fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C11H6ClF4N3OS, CAS 723735-24-8
2-(2-Chloro-6-fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 723735-24-8C11H6ClF4N3OS
2-(4-Chlorophenyl)-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C12H12ClN3OS2, CAS 544451-71-0
2-(4-Chlorophenyl)-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 544451-71-0C12H12ClN3OS2
N-[5-(2,2-Dimethylpropyl)-1,3,4-thiadiazol-2-yl]-2-(2-methoxyphenyl)acetamide chemical structure, C16H21N3O2S, CAS 510741-14-7
N-[5-(2,2-Dimethylpropyl)-1,3,4-thiadiazol-2-yl]-2-(2-methoxyphenyl)acetamide
CAS 510741-14-7C16H21N3O2S
2-(4-Fluorophenyl)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C13H14FN3OS, CAS 476463-02-2
2-(4-Fluorophenyl)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)acetamide
CAS 476463-02-2C13H14FN3OS
2-(2-Nitrophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C11H7F3N4O3S, CAS 636993-89-0
2-(2-Nitrophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 636993-89-0C11H7F3N4O3S
2-(4-Bromophenyl)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C13H14BrN3OS, CAS 524677-45-0
2-(4-Bromophenyl)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)acetamide
CAS 524677-45-0C13H14BrN3OS
2-(4-Methylphenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C12H10F3N3OS, CAS 587844-07-3
2-(4-Methylphenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 587844-07-3C12H10F3N3OS
2-(4-Methylphenyl)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C14H17N3OS, CAS 587844-17-5
2-(4-Methylphenyl)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)acetamide
CAS 587844-17-5C14H17N3OS