Murcko scaffold
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] benzoate scaffold
156 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 24
- Chemicals
- 156
- With full pages
- 13
Scaffold SMILES
O=C(Oc1coc(CSc2ncccn2)cc1=O)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 156 chemicals
![[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 3-fluorobenzoate chemical structure, C17H11FN2O4S, CAS 877636-18-5](/s/LYCDMUCCDXAMHA-UHFFFAOYSA-N.svg)
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 3-fluorobenzoate
CAS 877636-18-5C17H11FN2O4S
![[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3-fluorobenzoate chemical structure, C18H13FN2O4S, CAS 877636-20-9](/s/YRJOYYCOMOECCP-UHFFFAOYSA-N.svg)
[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3-fluorobenzoate
CAS 877636-20-9C18H13FN2O4S
![[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3-fluorobenzoate chemical structure, C19H15FN2O4S, CAS 877636-22-1](/s/SEUJSPSKTQSMLO-UHFFFAOYSA-N.svg)
[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3-fluorobenzoate
CAS 877636-22-1C19H15FN2O4S
![[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-fluorobenzoate chemical structure, C17H11FN2O4S, CAS 877636-24-3](/s/YNUFOGDPXFIWLJ-UHFFFAOYSA-N.svg)
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-fluorobenzoate
CAS 877636-24-3C17H11FN2O4S
![[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-fluorobenzoate chemical structure, C18H13FN2O4S, CAS 877636-26-5](/s/JEWTWBDJGAJPAB-UHFFFAOYSA-N.svg)
[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-fluorobenzoate
CAS 877636-26-5C18H13FN2O4S
![[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-fluorobenzoate chemical structure, C19H15FN2O4S, CAS 877636-28-7](/s/NUOAFRXWNDGDLK-UHFFFAOYSA-N.svg)
[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-fluorobenzoate
CAS 877636-28-7C19H15FN2O4S
![[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 2-chlorobenzoate chemical structure, C17H11ClN2O4S, CAS 877636-30-1](/s/VWGGUCPXKSYGBE-UHFFFAOYSA-N.svg)
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 2-chlorobenzoate
CAS 877636-30-1C17H11ClN2O4S
![[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 2-chlorobenzoate chemical structure, C18H13ClN2O4S, CAS 877635-61-5](/s/JTSZWZYKKWYLHY-UHFFFAOYSA-N.svg)
[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 2-chlorobenzoate
CAS 877635-61-5C18H13ClN2O4S
6-(((4,6-Dimethylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 2-chlorobenzoate
CAS 877635-63-7C19H15ClN2O4S
![[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 3-chlorobenzoate chemical structure, C17H11ClN2O4S, CAS 877635-65-9](/s/WCYXTVWOILNSLT-UHFFFAOYSA-N.svg)
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 3-chlorobenzoate
CAS 877635-65-9C17H11ClN2O4S
![[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3-chlorobenzoate chemical structure, C18H13ClN2O4S, CAS 877635-67-1](/s/RSJUVUUXFGNOHH-UHFFFAOYSA-N.svg)
[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3-chlorobenzoate
CAS 877635-67-1C18H13ClN2O4S
![[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3-chlorobenzoate chemical structure, C19H15ClN2O4S, CAS 877635-69-3](/s/VCUZPJGJXMDKGU-UHFFFAOYSA-N.svg)
[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3-chlorobenzoate
CAS 877635-69-3C19H15ClN2O4S
![[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-chlorobenzoate chemical structure, C17H11ClN2O4S, CAS 877635-71-7](/s/WPIFMQRIMCZIGY-UHFFFAOYSA-N.svg)
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-chlorobenzoate
CAS 877635-71-7C17H11ClN2O4S
![[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-chlorobenzoate chemical structure, C18H13ClN2O4S, CAS 877635-73-9](/s/OQGZHUFXDMTGPI-UHFFFAOYSA-N.svg)
[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-chlorobenzoate
CAS 877635-73-9C18H13ClN2O4S
![[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-chlorobenzoate chemical structure, C19H15ClN2O4S, CAS 877635-75-1](/s/UDNYDHWHEPFHHC-UHFFFAOYSA-N.svg)
[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-chlorobenzoate
CAS 877635-75-1C19H15ClN2O4S
4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 2,6-difluorobenzoate
CAS 877636-01-6C17H10F2N2O4S
![[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 2,6-difluorobenzoate chemical structure, C18H12F2N2O4S, CAS 877636-03-8](/s/JVRAURCDLIBCDS-UHFFFAOYSA-N.svg)
[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 2,6-difluorobenzoate
CAS 877636-03-8C18H12F2N2O4S
![[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 2,6-difluorobenzoate chemical structure, C19H14F2N2O4S, CAS 877636-05-0](/s/FRZBYSDBSYRGQC-UHFFFAOYSA-N.svg)
[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 2,6-difluorobenzoate
CAS 877636-05-0C19H14F2N2O4S
![[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 3,4-difluorobenzoate chemical structure, C17H10F2N2O4S, CAS 877636-07-2](/s/PFPJTGTYOYLMJD-UHFFFAOYSA-N.svg)
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 3,4-difluorobenzoate
CAS 877636-07-2C17H10F2N2O4S
![[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3,4-difluorobenzoate chemical structure, C18H12F2N2O4S, CAS 877636-09-4](/s/WKKCKVHOQFVKGS-UHFFFAOYSA-N.svg)
[6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3,4-difluorobenzoate
CAS 877636-09-4C18H12F2N2O4S
![[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3,4-difluorobenzoate chemical structure, C19H14F2N2O4S, CAS 877636-11-8](/s/GUXPHIRZQRIOMZ-UHFFFAOYSA-N.svg)
[6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3,4-difluorobenzoate
CAS 877636-11-8C19H14F2N2O4S
![[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 2,4-dichlorobenzoate chemical structure, C17H10Cl2N2O4S, CAS 877636-13-0](/s/YGXSQCPKGSMZCR-UHFFFAOYSA-N.svg)
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 2,4-dichlorobenzoate
CAS 877636-13-0C17H10Cl2N2O4S
![[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 2,5-dichlorobenzoate chemical structure, C17H10Cl2N2O4S, CAS 877636-19-6](/s/BKHWIVSVNWQNFI-UHFFFAOYSA-N.svg)
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 2,5-dichlorobenzoate
CAS 877636-19-6C17H10Cl2N2O4S
![[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 2-chloro-6-fluorobenzoate chemical structure, C17H10ClFN2O4S, CAS 877636-25-4](/s/VJISKANEUAYIFQ-UHFFFAOYSA-N.svg)
[4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 2-chloro-6-fluorobenzoate
CAS 877636-25-4C17H10ClFN2O4S
- [6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 2-chloro-6-fluorobenzoate877636-27-6C18H12ClFN2O4S
- [4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 5-chloro-2-methoxybenzoate877636-34-5C18H13ClN2O5S
- [4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 2-nitrobenzoate877636-36-7C17H11N3O6S
- 6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 2-nitrobenzoate877636-37-8C18H13N3O6S
- [6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 2-nitrobenzoate877636-38-9C19H15N3O6S
- [4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 3-nitrobenzoate877636-39-0C17H11N3O6S
- [6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3-nitrobenzoate877636-40-3C18H13N3O6S
- [6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 3-nitrobenzoate877636-41-4C19H15N3O6S
- 1 suppliers4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate877636-42-5C17H11N3O6S
- 4-Nitrobenzoic acid [6-[[(4-methyl-2-pyrimidinyl)thio]methyl]-4-oxo-3-pyranyl] ester877636-43-6C18H13N3O6S
- [6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-nitrobenzoate877636-44-7C19H15N3O6S
- [4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 2-methyl-3-nitrobenzoate877636-45-8C18H13N3O6S
- [6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 2-methyl-3-nitrobenzoate877636-46-9C19H15N3O6S
- 4-Methyl-3-nitrobenzoic acid [4-oxo-6-[(2-pyrimidinylthio)methyl]-3-pyranyl] ester877636-48-1C18H13N3O6S
- 4-Methyl-3-nitrobenzoic acid [6-[[(4-methyl-2-pyrimidinyl)thio]methyl]-4-oxo-3-pyranyl] ester877636-49-2C19H15N3O6S
- [4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 2-(trifluoromethyl)benzoate877636-60-7C18H11F3N2O4S
- [4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 3-(trifluoromethyl)benzoate877636-63-0C18H11F3N2O4S
- [4-Oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-(trifluoromethyl)benzoate877636-66-3C18H11F3N2O4S
- Methyl (4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl) phthalate877638-23-8C19H14N2O6S
- Methyl (6-(((4-methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl) phthalate877638-25-0C20H16N2O6S
- [6-[(4,6-Dimethylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-chloro-3-nitrobenzoate877636-59-4C19H14ClN3O6S
- 6-(((4,6-Dimethylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 4-(N,N-diethylsulfamoyl)benzoate877637-67-7C23H25N3O6S2
- 6-(((4-Methylpyrimidin-2-yl)thio)methyl)-4-oxo-4H-pyran-3-yl 2-chloro-5-nitrobenzoate877636-55-0C18H12ClN3O6S
- [6-[(4-Methylpyrimidin-2-yl)sulfanylmethyl]-4-oxopyran-3-yl] 4-chloro-3-nitrobenzoate877636-58-3C18H12ClN3O6S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1ccccc137 chemicals
O=C(Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1)c1ccccc119 chemicals
O=C(Nc1ccccc1)c1ccc(C(=O)Nc2ccccc2)cc119 chemicals
c1ccc(N=Nc2ccc(N=Nc3ccccc3)cc2)cc118 chemicals
O=C(Nc1ccc(NC(=O)c2ccccc2)cc1)c1ccccc116 chemicals
C(=Nc1ccc(N=Cc2ccccc2)cc1)c1ccccc116 chemicals
C(=Nc1ccccc1)c1ccc(C=Nc2ccccc2)cc116 chemicals
C(=Cc1ccc(C=Cc2ccccc2)cc1)c1ccccc112 chemicals
O=C(Oc1ccc(C(=O)Oc2ccccc2)cc1)c1ccccc112 chemicals
C(=Nc1ccccc1)c1ccc(OCc2ccccc2)cc111 chemicals
O=C(Nc1ccc(N=Nc2ccccc2)cc1)c1ccccc110 chemicals
O=C(Nc1ccc(S(=O)(=O)Nc2ccncn2)cc1)c1ccccc110 chemicals