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Murcko scaffold

Ring system with 2 rings and 19 atoms

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
18
With full pages
6
Scaffold SMILES

O=C(CSc1ccccn1)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ccccn1)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

N-[(E)-(4-Methylphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide chemical structure, C15H15N3OS, CAS 331425-11-7
N-[(E)-(4-Methylphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
CAS 331425-11-7C15H15N3OS
N-[(E)-(3,4-Dichlorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide chemical structure, C14H11Cl2N3OS, CAS 329062-38-6
N-[(E)-(3,4-Dichlorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
CAS 329062-38-6C14H11Cl2N3OS
N-[(E)-(4-Ethoxy-3-hydroxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide chemical structure, C16H17N3O3S, CAS 1029014-82-1
N-[(E)-(4-Ethoxy-3-hydroxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
CAS 1029014-82-1C16H17N3O3S
N-[(E)-(2-Methoxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide chemical structure, C15H15N3O2S, CAS 326000-88-8
N-[(E)-(2-Methoxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
CAS 326000-88-8C15H15N3O2S
N'-{(E)-[4-(dimethylamino)phenyl]methylidene}-2-(pyridin-2-ylsulfanyl)acetohydrazide chemical structure, C16H18N4OS, CAS 326000-67-3
N'-{(E)-[4-(dimethylamino)phenyl]methylidene}-2-(pyridin-2-ylsulfanyl)acetohydrazide
CAS 326000-67-3C16H18N4OS
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide chemical structure, C16H17N3O3S, CAS 1029014-73-0
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
CAS 1029014-73-0C16H17N3O3S
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide chemical structure, C14H11Cl2N3OS, CAS 326000-73-1
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
CAS 326000-73-1C14H11Cl2N3OS
N-[(E)-(4-Methoxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide chemical structure, C15H15N3O2S, CAS 326000-62-8
N-[(E)-(4-Methoxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
CAS 326000-62-8C15H15N3O2S
N-[(E)-Benzylideneamino]-2-pyridin-2-ylsulfanylacetamide chemical structure, C14H13N3OS, CAS 345324-09-6
N-[(E)-Benzylideneamino]-2-pyridin-2-ylsulfanylacetamide
CAS 345324-09-6C14H13N3OS
N-[(E)-(3-Methoxy-4-propoxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide chemical structure, C18H21N3O3S, CAS 342033-79-8
N-[(E)-(3-Methoxy-4-propoxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
CAS 342033-79-8C18H21N3O3S
N-[(E)-(3-Methoxy-4-propan-2-yloxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide chemical structure, C18H21N3O3S, CAS 342042-07-3
N-[(E)-(3-Methoxy-4-propan-2-yloxyphenyl)methylideneamino]-2-pyridin-2-ylsulfanylacetamide
CAS 342042-07-3C18H21N3O3S
N-[(E)-[4-(Diethylamino)phenyl]methylideneamino]-2-pyridin-2-ylsulfanylacetamide chemical structure, C18H22N4OS, CAS 326000-68-4
N-[(E)-[4-(Diethylamino)phenyl]methylideneamino]-2-pyridin-2-ylsulfanylacetamide
CAS 326000-68-4C18H22N4OS
N'-[(E)-(4-Nitrophenyl)methylidene]-2-(pyridin-2-ylsulfanyl)acetohydrazide chemical structure, C14H12N4O3S, CAS 326000-56-0
N'-[(E)-(4-Nitrophenyl)methylidene]-2-(pyridin-2-ylsulfanyl)acetohydrazide
CAS 326000-56-0C14H12N4O3S
(E)-N'-(4-Hydroxybenzylidene)-2-(pyridin-2-ylthio)acetohydrazide chemical structure, C14H13N3O2S, CAS 326000-78-6
(E)-N'-(4-Hydroxybenzylidene)-2-(pyridin-2-ylthio)acetohydrazide
CAS 326000-78-6C14H13N3O2S
N'-[(E)-(2,4-Dihydroxyphenyl)methylidene]-2-(pyridin-2-ylsulfanyl)acetohydrazide chemical structure, C14H13N3O3S, CAS 326000-58-2
N'-[(E)-(2,4-Dihydroxyphenyl)methylidene]-2-(pyridin-2-ylsulfanyl)acetohydrazide
CAS 326000-58-2C14H13N3O3S
N'-[(E)-(4-Hydroxy-3-methoxyphenyl)methylidene]-2-(pyridin-2-ylsulfanyl)acetohydrazide chemical structure, C15H15N3O3S, CAS 326000-60-6
N'-[(E)-(4-Hydroxy-3-methoxyphenyl)methylidene]-2-(pyridin-2-ylsulfanyl)acetohydrazide
CAS 326000-60-6C15H15N3O3S
2-(2-Pyridinylthio)propanoic acid 2-[(2,4-dihydroxyphenyl)methylene]hydrazide chemical structure, C15H15N3O3S, CAS 347908-94-5
2-(2-Pyridinylthio)propanoic acid 2-[(2,4-dihydroxyphenyl)methylene]hydrazide
CAS 347908-94-5C15H15N3O3S
2-(2-Pyridinylthio)propanoic acid 2-[(3-fluorophenyl)methylene]hydrazide chemical structure, C15H14FN3OS, CAS 677741-08-1
2-(2-Pyridinylthio)propanoic acid 2-[(3-fluorophenyl)methylene]hydrazide
CAS 677741-08-1C15H14FN3OS