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Murcko scaffold

2-(Thiophen-2-yl)-1,3,4-oxadiazole scaffold

69 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
69
With full pages
10
Scaffold SMILES

c1csc(-c2nnco2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Thiophen-2-yl)-1,3,4-oxadiazole page
Murcko scaffold c1csc(-c2nnco2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 69 chemicals

1,3,4-Oxadiazole, 2-methylthio-5-(2-thienyl)- chemical structure, C7H6N2OS2, CAS 89795-53-9
1,3,4-Oxadiazole, 2-methylthio-5-(2-thienyl)-
CAS 89795-53-9C7H6N2OS2
{[5-(2-Thienyl)-1,3,4-oxadiazol-2-yl]thio}acetic acid chemical structure, C8H6N2O3S2, CAS 485334-94-9
{[5-(2-Thienyl)-1,3,4-oxadiazol-2-yl]thio}acetic acid
CAS 485334-94-9C8H6N2O3S2
(5-Thiophen-2-yl-[1,3,4]oxadiazol-2-ylsulfanyl)-acetic acid methyl ester chemical structure, C9H8N2O3S2, CAS 459846-03-8
(5-Thiophen-2-yl-[1,3,4]oxadiazol-2-ylsulfanyl)-acetic acid methyl ester
CAS 459846-03-8C9H8N2O3S2
Ethyl 2-{[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetate chemical structure, C10H10N2O3S2, CAS 459846-02-7
Ethyl 2-{[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetate
CAS 459846-02-7C10H10N2O3S2
2-{[5-(2-Thienyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide chemical structure, C8H7N3O2S2, CAS 459846-01-6
2-{[5-(2-Thienyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide
CAS 459846-01-6C8H7N3O2S2
N-(5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)pivalamide chemical structure, C11H13N3O2S, CAS 865287-97-4
N-(5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)pivalamide
CAS 865287-97-4C11H13N3O2S
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]propanamide chemical structure, C9H8ClN3O2S, CAS 865543-65-3
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]propanamide
CAS 865543-65-3C9H8ClN3O2S
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]pentanamide chemical structure, C11H12ClN3O2S, CAS 865543-67-5
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]pentanamide
CAS 865543-67-5C11H12ClN3O2S
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]-2,2-dimethylpropanamide chemical structure, C11H12ClN3O2S, CAS 865543-68-6
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]-2,2-dimethylpropanamide
CAS 865543-68-6C11H12ClN3O2S
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]butanamide chemical structure, C10H10ClN3O2S, CAS 865543-73-3
N-[5-(5-Chlorothiophen-2-yl)-1,3,4-oxadiazol-2-yl]butanamide
CAS 865543-73-3C10H10ClN3O2S
2-(Chloromethyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole chemical structure, C7H5ClN2OS, CAS 727374-87-0
2-(Chloromethyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole
CAS 727374-87-0C7H5ClN2OS
2-(Thiophen-2-yl)-1,3,4-oxadiazole chemical structure, C6H4N2OS, CAS 35403-88-4
2-(Thiophen-2-yl)-1,3,4-oxadiazole
CAS 35403-88-4C6H4N2OS
2-[[5-(2-Thienyl)-1,3,4-oxadiazol-2-yl]thio]acetonitrile chemical structure, C8H5N3OS2, CAS 485334-95-0
2-[[5-(2-Thienyl)-1,3,4-oxadiazol-2-yl]thio]acetonitrile
CAS 485334-95-0C8H5N3OS2
(2-Methoxyethyl)({[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]methyl})amine chemical structure, C10H13N3O2S, CAS 900640-76-8
(2-Methoxyethyl)({[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]methyl})amine
CAS 900640-76-8C10H13N3O2S
Propyl({[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]methyl})amine chemical structure, C10H13N3OS, CAS 900641-38-5
Propyl({[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]methyl})amine
CAS 900641-38-5C10H13N3OS
N-(5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)isobutyramide chemical structure, C10H11N3O2S, CAS 941997-88-2
N-(5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)isobutyramide
CAS 941997-88-2C10H11N3O2S
2-(Chloromethyl)-5-(5-ethyl-4-methylthiophen-2-yl)-1,3,4-oxadiazole chemical structure, C10H11ClN2OS, CAS 796106-51-9
2-(Chloromethyl)-5-(5-ethyl-4-methylthiophen-2-yl)-1,3,4-oxadiazole
CAS 796106-51-9C10H11ClN2OS
2-(1-Chloroethyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole chemical structure, C8H7ClN2OS, CAS 854357-49-6
2-(1-Chloroethyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole
CAS 854357-49-6C8H7ClN2OS
2-(5-Bromothiophen-2-yl)-5-(chloromethyl)-1,3,4-oxadiazole chemical structure, C7H4BrClN2OS, CAS 848658-82-2
2-(5-Bromothiophen-2-yl)-5-(chloromethyl)-1,3,4-oxadiazole
CAS 848658-82-2C7H4BrClN2OS
N-(2-Cyano-3-methylbutan-2-yl)-2-((5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide chemical structure, C14H16N4O2S2, CAS 781632-57-3
N-(2-Cyano-3-methylbutan-2-yl)-2-((5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide
CAS 781632-57-3C14H16N4O2S2
N-(5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)acetamide chemical structure, C8H7N3O2S, CAS 27049-77-0
N-(5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)acetamide
CAS 27049-77-0C8H7N3O2S
2-Chloro-N-propyl-N-[(5-thien-2-yl-1,3,4-oxadiazol-2-yl)methyl]acetamide chemical structure, C12H14ClN3O2S, CAS 878465-33-9
2-Chloro-N-propyl-N-[(5-thien-2-yl-1,3,4-oxadiazol-2-yl)methyl]acetamide
CAS 878465-33-9C12H14ClN3O2S
2-Methyl-5-(thiophen-2-yl)-1,3,4-oxadiazole chemical structure, C7H6N2OS, CAS 209592-81-4
2-Methyl-5-(thiophen-2-yl)-1,3,4-oxadiazole
CAS 209592-81-4C7H6N2OS
N-(2-Methoxyethyl)-N-[(5-thien-2-yl-1,3,4-oxadiazol-2-yl)methyl]amine hydrochloride chemical structure, C10H14ClN3O2S, CAS 1052543-77-7
N-(2-Methoxyethyl)-N-[(5-thien-2-yl-1,3,4-oxadiazol-2-yl)methyl]amine hydrochloride
CAS 1052543-77-7C10H14ClN3O2S