CompoundList
Murcko scaffold

2-(Thiophen-2-yl)-1,3,4-oxadiazole scaffold

69 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
69
With full pages
10
Scaffold SMILES

c1csc(-c2nnco2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Murcko scaffold c1csc(-c2nnco2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 69 of 69 chemicals

2-[5-(3-Methylthiophen-2-yl)-1,3,4-oxadiazol-2-yl]acetohydrazide chemical structure, C9H10N4O2S, CAS 1325305-34-7
2-[5-(3-Methylthiophen-2-yl)-1,3,4-oxadiazol-2-yl]acetohydrazide
CAS 1325305-34-7C9H10N4O2S
2-[5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl]acetohydrazide chemical structure, C8H8N4O2S, CAS 1338652-34-8
2-[5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl]acetohydrazide
CAS 1338652-34-8C8H8N4O2S
2-tert-Butyloxycarbonylaminomethyl-5-thiophen-2-YL-[1,3,4]oxadiazole chemical structure, C12H15N3O3S, CAS 1053656-68-0
2-tert-Butyloxycarbonylaminomethyl-5-thiophen-2-YL-[1,3,4]oxadiazole
CAS 1053656-68-0C12H15N3O3S
2-(3-Bromothien-2-yl)-1,3,4-oxadiazole chemical structure, C6H3BrN2OS, CAS 1357064-43-7
2-(3-Bromothien-2-yl)-1,3,4-oxadiazole
CAS 1357064-43-7C6H3BrN2OS
2-(3-Methyl-2-thienyl)-1,3,4-oxadiazole chemical structure, C7H6N2OS, CAS 1171930-11-2
2-(3-Methyl-2-thienyl)-1,3,4-oxadiazole
CAS 1171930-11-2C7H6N2OS
2-Methoxy-N-[5-(4-methylthiophen-2-yl)-1,3,4-oxadiazol-2-yl]acetamide chemical structure, C10H11N3O3S, CAS 1396848-80-8
2-Methoxy-N-[5-(4-methylthiophen-2-yl)-1,3,4-oxadiazol-2-yl]acetamide
CAS 1396848-80-8C10H11N3O3S
Ethyl 4-((5-(4-methylthiophen-2-yl)-1,3,4-oxadiazol-2-yl)amino)-4-oxobutanoate chemical structure, C13H15N3O4S, CAS 1396885-66-7
Ethyl 4-((5-(4-methylthiophen-2-yl)-1,3,4-oxadiazol-2-yl)amino)-4-oxobutanoate
CAS 1396885-66-7C13H15N3O4S
1,3,4-Oxadiazole-2-ethanamine, 5-(4-bromo-2-thienyl)- chemical structure, C8H8BrN3OS, CAS 1368440-03-2
1,3,4-Oxadiazole-2-ethanamine, 5-(4-bromo-2-thienyl)-
CAS 1368440-03-2C8H8BrN3OS
Methyl 5-(thiophen-2-yl)-1,3,4-oxadiazole-2-carboxylate chemical structure, C8H6N2O3S, CAS 35403-82-8
Methyl 5-(thiophen-2-yl)-1,3,4-oxadiazole-2-carboxylate
CAS 35403-82-8C8H6N2O3S
N-Propyl-N-{[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]methyl}prop-2-enamide chemical structure, C13H15N3O2S, CAS 2094406-50-3
N-Propyl-N-{[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]methyl}prop-2-enamide
CAS 2094406-50-3C13H15N3O2S
2-(1,3,4-Oxadiazol-2-yl)thiophen-3-amine chemical structure, C6H5N3OS, CAS 1379313-91-3
2-(1,3,4-Oxadiazol-2-yl)thiophen-3-amine
CAS 1379313-91-3C6H5N3OS
2-Chloro-N-propyl-N-{[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]methyl}propanamide chemical structure, C13H16ClN3O2S, CAS 2411275-75-5
2-Chloro-N-propyl-N-{[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]methyl}propanamide
CAS 2411275-75-5C13H16ClN3O2S
N-Propyl-N-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)methyl]but-2-ynamide chemical structure, C14H15N3O2S, CAS 2411235-14-6
N-Propyl-N-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)methyl]but-2-ynamide
CAS 2411235-14-6C14H15N3O2S
(E)-4-(Dimethylamino)-N-propyl-N-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)methyl]but-2-enamide chemical structure, C16H22N4O2S, CAS 2411334-57-9
(E)-4-(Dimethylamino)-N-propyl-N-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)methyl]but-2-enamide
CAS 2411334-57-9C16H22N4O2S
Potassium 5-(thiophen-2-yl)-1,3,4-oxadiazole-2-carboxylate chemical structure, C7H3KN2O3S, CAS 1644298-56-5
Potassium 5-(thiophen-2-yl)-1,3,4-oxadiazole-2-carboxylate
CAS 1644298-56-5C7H3KN2O3S
5-(5-Methyl-1,3,4-oxadiazol-2-yl)thiophene-2-carbaldehyde chemical structure, C8H6N2O2S, CAS 2138205-03-3
5-(5-Methyl-1,3,4-oxadiazol-2-yl)thiophene-2-carbaldehyde
CAS 2138205-03-3C8H6N2O2S
5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]thiophene-2-carbaldehyde chemical structure, C8H4F2N2O2S, CAS 2137697-89-1
5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]thiophene-2-carbaldehyde
CAS 2137697-89-1C8H4F2N2O2S
5-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)thiophene-2-carbaldehyde chemical structure, C11H12N2O2S, CAS 2137760-60-0
5-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)thiophene-2-carbaldehyde
CAS 2137760-60-0C11H12N2O2S
5-[5-(Propan-2-yl)-1,3,4-oxadiazol-2-yl]thiophene-2-carbaldehyde chemical structure, C10H10N2O2S, CAS 2137760-65-5
5-[5-(Propan-2-yl)-1,3,4-oxadiazol-2-yl]thiophene-2-carbaldehyde
CAS 2137760-65-5C10H10N2O2S
3-[5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl]propan-1-amine hydrochloride chemical structure, C9H12ClN3OS, CAS 2680532-99-2
3-[5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl]propan-1-amine hydrochloride
CAS 2680532-99-2C9H12ClN3OS
N-Methyl-5-(thiophen-2-yl)-1,3,4-oxadiazol-2-amine chemical structure, C7H7N3OS, CAS 2932438-77-0
N-Methyl-5-(thiophen-2-yl)-1,3,4-oxadiazol-2-amine
CAS 2932438-77-0C7H7N3OS