Murcko scaffold
2-(Thiophen-2-yl)-1,3,4-oxadiazole scaffold
69 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 69
- With full pages
- 10
Scaffold SMILES
c1csc(-c2nnco2)c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 69 of 69 chemicals
2-[5-(3-Methylthiophen-2-yl)-1,3,4-oxadiazol-2-yl]acetohydrazide
CAS 1325305-34-7C9H10N4O2S
2-[5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl]acetohydrazide
CAS 1338652-34-8C8H8N4O2S
2-tert-Butyloxycarbonylaminomethyl-5-thiophen-2-YL-[1,3,4]oxadiazole
CAS 1053656-68-0C12H15N3O3S
2-(3-Bromothien-2-yl)-1,3,4-oxadiazole
CAS 1357064-43-7C6H3BrN2OS
2-(3-Methyl-2-thienyl)-1,3,4-oxadiazole
CAS 1171930-11-2C7H6N2OS
2-Methoxy-N-[5-(4-methylthiophen-2-yl)-1,3,4-oxadiazol-2-yl]acetamide
CAS 1396848-80-8C10H11N3O3S
Ethyl 4-((5-(4-methylthiophen-2-yl)-1,3,4-oxadiazol-2-yl)amino)-4-oxobutanoate
CAS 1396885-66-7C13H15N3O4S
1,3,4-Oxadiazole-2-ethanamine, 5-(4-bromo-2-thienyl)-
CAS 1368440-03-2C8H8BrN3OS
Methyl 5-(thiophen-2-yl)-1,3,4-oxadiazole-2-carboxylate
CAS 35403-82-8C8H6N2O3S
N-Propyl-N-{[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]methyl}prop-2-enamide
CAS 2094406-50-3C13H15N3O2S
2-(1,3,4-Oxadiazol-2-yl)thiophen-3-amine
CAS 1379313-91-3C6H5N3OS
2-Chloro-N-propyl-N-{[5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl]methyl}propanamide
CAS 2411275-75-5C13H16ClN3O2S
N-Propyl-N-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)methyl]but-2-ynamide
CAS 2411235-14-6C14H15N3O2S
(E)-4-(Dimethylamino)-N-propyl-N-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)methyl]but-2-enamide
CAS 2411334-57-9C16H22N4O2S
Potassium 5-(thiophen-2-yl)-1,3,4-oxadiazole-2-carboxylate
CAS 1644298-56-5C7H3KN2O3S
5-(5-Methyl-1,3,4-oxadiazol-2-yl)thiophene-2-carbaldehyde
CAS 2138205-03-3C8H6N2O2S
5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]thiophene-2-carbaldehyde
CAS 2137697-89-1C8H4F2N2O2S
5-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)thiophene-2-carbaldehyde
CAS 2137760-60-0C11H12N2O2S
5-[5-(Propan-2-yl)-1,3,4-oxadiazol-2-yl]thiophene-2-carbaldehyde
CAS 2137760-65-5C10H10N2O2S
3-[5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl]propan-1-amine hydrochloride
CAS 2680532-99-2C9H12ClN3OS
N-Methyl-5-(thiophen-2-yl)-1,3,4-oxadiazol-2-amine
CAS 2932438-77-0C7H7N3OS