Murcko scaffold
Ring system with 2 rings and 18 atoms
34 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 18
- Chemicals
- 34
- With full pages
- 5
Scaffold SMILES
O=C(CNC(=O)C1CCCN1)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 34 of 34 chemicals
Isoleucyl-prolyl-arginine-4-nitroanilide
CAS 77672-35-6C23H36N8O5
Ac-IEPD-PNA
CAS 216757-29-8C28H38N6O11
Meosuc-aapm-pna
CAS 70967-91-8C27H38N6O9S
Suc-Ala-Pro-Ala-pNA
CAS 72682-79-2C21H27N5O8
![L-Argininamide, D-valyl-L-prolyl-N-[4-[ethyl(2-hydroxyethyl)amino]phenyl]- chemical structure, C26H44N8O4, CAS 105434-91-1](/s/HOZPRZNZIQVYTH-FDFHNCONSA-N.svg)
L-Argininamide, D-valyl-L-prolyl-N-[4-[ethyl(2-hydroxyethyl)amino]phenyl]-
CAS 105434-91-1C26H44N8O4
Boc-Ala-Ala-Pro-Ala-pNA
CAS 121570-42-1C25H36N6O8
AC-Ala-pro-ala-pna
CAS 61596-39-2C19H25N5O6
N-Methylglycylprolyl-N~5~-(diaminomethylidene)-N-(4-nitrophenyl)ornithinamide--hydrogen chloride (1/1)
CAS 75241-23-5C20H31ClN8O5
D-Ile-Pro-Arg p-nitroanilide dihydrochloride
CAS 96323-41-0C23H38Cl2N8O5
Sar-Pro-Arg-pNA
CAS 77695-30-8C20H30N8O5
L-Alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide
CAS 90105-48-9C22H32N6O6
Suc-Ala-Ala-Pro-Lys-pNA
CAS 108929-39-1C27H39N7O9
Suc-ala-ala-pro-leu-pna
CAS 70968-04-6C27H38N6O9
N-Acetyl-L-alanyl-L-seryl-L-prolyl-N-(4-nitrophenyl)-L-lysinamide
CAS 194670-72-9C25H37N7O8
L-Argininamide, 1-acetyl-L-prolyl-N-(4-nitrophenyl)-
CAS 103418-62-8C19H27N7O5
1-Acetyl-L-prolyl-N-(4-nitrophenyl)-L-leucinamide
CAS 64709-51-9C19H26N4O5
Suc-ala-ala-pro-val-pna
CAS 72682-76-9C26H36N6O9
Succinyl-L-alanyl-L-prolyl-L-alanine p-nitroanilide
C21H27N5O8
Ac-DL-Ala-DL-Ala-DL-Pro-DL-Ala-pNA
C22H30N6O7
Suc-ala-ala-pro-arg-pna
CAS 131068-47-8C27H39N9O9
h-Ala-ala-pro-leu-pna hcl
CAS 201732-32-3C23H35ClN6O6
Suc-ala-ala-pro-ala-pna
CAS 72682-69-0C24H32N6O9
Suc-ala-ala-pro-nle-pna
CAS 72682-72-5C27H38N6O9
Suc-ala-ala-pro-ile-pna
CAS 72682-77-0C27H38N6O9
- 1 suppliersAC-Ala-ala-pro-ala-pna96699-74-0C22H30N6O7
- 1 suppliersAc-Ala-Ala-Pro-Val-pNA133261-53-7C24H34N6O7
- Suc-Ala-Ala-Pro-Met-pNA72682-73-6C26H36N6O9S
- Suc-ala-ala-pro-glu-pna108929-37-9C26H34N6O11
- Suc-Ala-Ala-Pro-Nva-pNA72682-71-4C26H36N6O9
- N-Succinyl-Ala-Ala-Pro-Asp-p-nitroanilide165174-58-3C25H32N6O11
- Suc-AAP-Abu-pNA108392-27-4C25H34N6O9
- L-Argininamide, N-acetyl-L-alanyl-L-alanyl-O-phosphono-L-seryl-L-prolyl-N-(4-nitrophenyl)-(9CI)202739-37-5C28H43N10O12P
- Sar-Pro-Arg-pNA Hydrochloride210158-97-7C20H31ClN8O5
- Suc-DL-Ala-DL-Ala-DL-Pro-DL-Nva-pNAC26H36N6O9
Related scaffolds
Same ring framework with different atoms or bond orders
C(=CC1CCCC1)CCOc1ccccc137 chemicals
O=C(NCCCn1ccnc1)c1ccccc122 chemicals
O=S(=O)(NCCCn1ccnc1)c1ccccc120 chemicals
O=C(COC(=O)c1ccccc1)NC1CCCC117 chemicals
O=C(COc1ccccc1)NCC1CCCO117 chemicals
S=C(NCCc1ccccc1)Nc1nccs116 chemicals
O=C(CCS(=O)(=O)c1ccccc1)Nc1cccs113 chemicals![Scaffold O=C(CSc1ncn[nH]1)NCc1ccccc1](/scaffold/ZBSYLOJDGBMFAD-UHFFFAOYSA-N/structure.svg)
O=C(CSc1ncn[nH]1)NCc1ccccc113 chemicals
O=C(Cn1cccn1)NN=Cc1ccccc112 chemicals
O=C(NCC1CCCO1)C(=O)Nc1ccccc112 chemicals![Scaffold O=C(Cc1ccc[nH]1)NN=Cc1ccccc1](/scaffold/XCXHYNVYLRCCIP-UHFFFAOYSA-N/structure.svg)
O=C(Cc1ccc[nH]1)NN=Cc1ccccc112 chemicals![Scaffold O=C(NNC(=S)Nc1ccccc1)c1cc[nH]n1](/scaffold/GFTUZBZNWRQYBL-UHFFFAOYSA-N/structure.svg)
O=C(NNC(=S)Nc1ccccc1)c1cc[nH]n111 chemicals