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Murcko scaffold

1-(2-Phenylethyl)-3-[(2-phenylethyl)amino]pyrrolidine-2,5-dione scaffold

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
8
With full pages
7
Scaffold SMILES

O=C1CC(NCCc2ccccc2)C(=O)N1CCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Phenylethyl)-3-[(2-phenylethyl)amino]pyrrolidine-2,5-dione page
Murcko scaffold O=C1CC(NCCc2ccccc2)C(=O)N1CCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

1-(2-Phenylethyl)-3-[(2-phenylethyl)amino]pyrrolidine-2,5-dione chemical structure, C20H22N2O2, CAS 178275-31-5
1-(2-Phenylethyl)-3-[(2-phenylethyl)amino]pyrrolidine-2,5-dione
CAS 178275-31-5C20H22N2O2
3-{[2-(4-Methoxyphenyl)ethyl]amino}-1-(2-phenylethyl)pyrrolidine-2,5-dione chemical structure, C21H24N2O3, CAS 5602-16-4
3-{[2-(4-Methoxyphenyl)ethyl]amino}-1-(2-phenylethyl)pyrrolidine-2,5-dione
CAS 5602-16-4C21H24N2O3
3-{[2-(3,4-Dimethoxyphenyl)ethyl]amino}-1-(2-phenylethyl)pyrrolidine-2,5-dione chemical structure, C22H26N2O4, CAS 340703-41-5
3-{[2-(3,4-Dimethoxyphenyl)ethyl]amino}-1-(2-phenylethyl)pyrrolidine-2,5-dione
CAS 340703-41-5C22H26N2O4
1-[2-(3,4-Dimethoxyphenyl)ethyl]-3-[2-(4-methoxyphenyl)ethylamino]pyrrolidine-2,5-dione chemical structure, C23H28N2O5, CAS 340017-54-1
1-[2-(3,4-Dimethoxyphenyl)ethyl]-3-[2-(4-methoxyphenyl)ethylamino]pyrrolidine-2,5-dione
CAS 340017-54-1C23H28N2O5
1-[2-(3,4-Dimethoxyphenyl)ethyl]-3-[2-(3,4-dimethoxyphenyl)ethylamino]pyrrolidine-2,5-dione chemical structure, C24H30N2O6, CAS 330945-85-2
1-[2-(3,4-Dimethoxyphenyl)ethyl]-3-[2-(3,4-dimethoxyphenyl)ethylamino]pyrrolidine-2,5-dione
CAS 330945-85-2C24H30N2O6
4-[2-({1-[2-(3,4-Dimethoxyphenyl)ethyl]-2,5-dioxo-3-pyrrolidinyl}amino)ethyl]benzenesulfonamide chemical structure, C22H27N3O6S, CAS 330945-86-3
4-[2-({1-[2-(3,4-Dimethoxyphenyl)ethyl]-2,5-dioxo-3-pyrrolidinyl}amino)ethyl]benzenesulfonamide
CAS 330945-86-3C22H27N3O6S
3-{[2-(4-Chlorophenyl)ethyl]amino}-1-(2-phenylethyl)pyrrolidine-2,5-dione chemical structure, C20H21ClN2O2, CAS 355138-37-3
3-{[2-(4-Chlorophenyl)ethyl]amino}-1-(2-phenylethyl)pyrrolidine-2,5-dione
CAS 355138-37-3C20H21ClN2O2
4-[2-[[2,5-Dioxo-1-(2-phenylethyl)pyrrolidin-3-yl]amino]ethyl]benzenesulfonamide chemical structure, C20H23N3O4S, CAS 342431-48-5
4-[2-[[2,5-Dioxo-1-(2-phenylethyl)pyrrolidin-3-yl]amino]ethyl]benzenesulfonamide
CAS 342431-48-5C20H23N3O4S