CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

41 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
41
With full pages
9
Scaffold SMILES

O=C(NCc1nnc(SCc2ccccc2)[nH]1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1nnc(SCc2ccccc2)[nH]1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 41 of 41 chemicals

2-Fluoro-N-({5-[(4-fluorobenzyl)sulfanyl]-4-methyl-4H-1,2,4-triazol-3-yl}methyl)benzamide chemical structure, C18H16F2N4OS, CAS 723244-93-7
2-Fluoro-N-({5-[(4-fluorobenzyl)sulfanyl]-4-methyl-4H-1,2,4-triazol-3-yl}methyl)benzamide
CAS 723244-93-7C18H16F2N4OS
3,4-Dimethoxy-N-[[4-methyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C20H21N5O5S, CAS 713490-54-1
3,4-Dimethoxy-N-[[4-methyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]benzamide
CAS 713490-54-1C20H21N5O5S
2-Bromo-N-[[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C18H15BrCl2N4OS, CAS 717860-77-0
2-Bromo-N-[[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]benzamide
CAS 717860-77-0C18H15BrCl2N4OS
N-[(5-{[4-(tert-Butyl)benzyl]sulfanyl}-4-ethyl-4H-1,2,4-triazol-3-yl)methyl]-4-chlorobenzenecarboxamide chemical structure, C23H27ClN4OS, CAS 338962-52-0
N-[(5-{[4-(tert-Butyl)benzyl]sulfanyl}-4-ethyl-4H-1,2,4-triazol-3-yl)methyl]-4-chlorobenzenecarboxamide
CAS 338962-52-0C23H27ClN4OS
4-Chloro-N-[[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C19H17Cl3N4OS, CAS 478049-27-3
4-Chloro-N-[[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]methyl]benzamide
CAS 478049-27-3C19H17Cl3N4OS
N-[[5-[(4-Chlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]-2-fluorobenzamide chemical structure, C18H16ClFN4OS, CAS 708215-77-4
N-[[5-[(4-Chlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]-2-fluorobenzamide
CAS 708215-77-4C18H16ClFN4OS
N-[[5-[(4-Fluorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]-3-methylbenzamide chemical structure, C19H19FN4OS, CAS 708251-33-6
N-[[5-[(4-Fluorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]-3-methylbenzamide
CAS 708251-33-6C19H19FN4OS
4-Methoxy-N-[[4-methyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C20H22N4O2S, CAS 708244-24-0
4-Methoxy-N-[[4-methyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]benzamide
CAS 708244-24-0C20H22N4O2S
N-[[5-[(4-Fluorophenyl)methylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]methyl]-3,4-dimethoxybenzamide chemical structure, C22H23FN4O3S, CAS 708280-17-5
N-[[5-[(4-Fluorophenyl)methylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]methyl]-3,4-dimethoxybenzamide
CAS 708280-17-5C22H23FN4O3S
N-[[5-[(4-Bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]methyl]-3-methylbenzamide chemical structure, C20H21BrN4OS, CAS 708294-16-0
N-[[5-[(4-Bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]methyl]-3-methylbenzamide
CAS 708294-16-0C20H21BrN4OS
4-Methoxy-N-[[4-methyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C19H19N5O4S, CAS 767326-27-2
4-Methoxy-N-[[4-methyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]benzamide
CAS 767326-27-2C19H19N5O4S
2-Bromo-N-[1-[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]ethyl]benzamide chemical structure, C20H19BrCl2N4OS, CAS 701287-92-5
2-Bromo-N-[1-[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]ethyl]benzamide
CAS 701287-92-5C20H19BrCl2N4OS
N-[[5-[(2,4-Dichlorophenyl)methylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]methyl]-3-methylbenzamide chemical structure, C21H20Cl2N4OS, CAS 706772-97-6
N-[[5-[(2,4-Dichlorophenyl)methylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]methyl]-3-methylbenzamide
CAS 706772-97-6C21H20Cl2N4OS
N-(1-{5-[(4-Fluorobenzyl)sulfanyl]-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl}ethyl)benzamide chemical structure, C21H21FN4OS, CAS 708237-85-8
N-(1-{5-[(4-Fluorobenzyl)sulfanyl]-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl}ethyl)benzamide
CAS 708237-85-8C21H21FN4OS
3,4-Dichloro-N-[1-[5-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]ethyl]benzamide chemical structure, C20H19Cl3N4OS, CAS 708248-85-5
3,4-Dichloro-N-[1-[5-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]ethyl]benzamide
CAS 708248-85-5C20H19Cl3N4OS
3,4-Dichloro-N-[[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C18H14Cl4N4OS, CAS 708280-56-2
3,4-Dichloro-N-[[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]benzamide
CAS 708280-56-2C18H14Cl4N4OS
N-[1-[5-[(4-Bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-2-methylpropyl]benzamide chemical structure, C22H25BrN4OS, CAS 708293-57-6
N-[1-[5-[(4-Bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-2-methylpropyl]benzamide
CAS 708293-57-6C22H25BrN4OS
N-[1-[5-[(4-Nitrophenyl)methylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]ethyl]benzamide chemical structure, C21H21N5O3S, CAS 767344-43-4
N-[1-[5-[(4-Nitrophenyl)methylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]ethyl]benzamide
CAS 767344-43-4C21H21N5O3S
2-Bromo-N-(1-{4-methyl-5-[(4-nitrobenzyl)sulfanyl]-4H-1,2,4-triazol-3-yl}ethyl)benzamide chemical structure, C19H18BrN5O3S, CAS 713493-67-5
2-Bromo-N-(1-{4-methyl-5-[(4-nitrobenzyl)sulfanyl]-4H-1,2,4-triazol-3-yl}ethyl)benzamide
CAS 713493-67-5C19H18BrN5O3S
N-[1-[5-[(3,4-Dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]ethyl]-4-methoxybenzamide chemical structure, C20H20Cl2N4O2S, CAS 767325-57-5
N-[1-[5-[(3,4-Dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]ethyl]-4-methoxybenzamide
CAS 767325-57-5C20H20Cl2N4O2S
N-(1-{5-[(3,4-Dichlorobenzyl)sulfanyl]-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl}-2-hydroxyethyl)-4-methoxybenzamide chemical structure, C22H22Cl2N4O3S, CAS 767325-62-2
N-(1-{5-[(3,4-Dichlorobenzyl)sulfanyl]-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl}-2-hydroxyethyl)-4-methoxybenzamide
CAS 767325-62-2C22H22Cl2N4O3S
N-(1-{5-[(3,4-Dichlorobenzyl)sulfanyl]-4-ethyl-4H-1,2,4-triazol-3-yl}ethyl)-4-methoxybenzamide chemical structure, C21H22Cl2N4O2S, CAS 767325-58-6
N-(1-{5-[(3,4-Dichlorobenzyl)sulfanyl]-4-ethyl-4H-1,2,4-triazol-3-yl}ethyl)-4-methoxybenzamide
CAS 767325-58-6C21H22Cl2N4O2S
N-(1-{5-[(3,4-Dichlorobenzyl)sulfanyl]-4-methyl-4H-1,2,4-triazol-3-yl}-2-hydroxyethyl)-4-methoxybenzamide chemical structure, C20H20Cl2N4O3S, CAS 767325-61-1
N-(1-{5-[(3,4-Dichlorobenzyl)sulfanyl]-4-methyl-4H-1,2,4-triazol-3-yl}-2-hydroxyethyl)-4-methoxybenzamide
CAS 767325-61-1C20H20Cl2N4O3S
N-(1-{5-[(3,4-Dichlorobenzyl)sulfanyl]-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl}ethyl)-2-fluorobenzamide chemical structure, C21H19Cl2FN4OS, CAS 767325-56-4
N-(1-{5-[(3,4-Dichlorobenzyl)sulfanyl]-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl}ethyl)-2-fluorobenzamide
CAS 767325-56-4C21H19Cl2FN4OS