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Murcko scaffold

Ring system with 3 rings and 23 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
15
With full pages
2
Scaffold SMILES

O=C(Cc1nnc(SCc2ccccc2)[nH]1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1nnc(SCc2ccccc2)[nH]1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

N-(3-Methoxyphenyl)-2-[4-methyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]acetamide chemical structure, C19H19N5O4S, CAS 713491-17-9
N-(3-Methoxyphenyl)-2-[4-methyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]acetamide
CAS 713491-17-9C19H19N5O4S
2-[5-[(4-Chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-N-(3,4-dichlorophenyl)acetamide chemical structure, C19H17Cl3N4OS, CAS 701281-09-6
2-[5-[(4-Chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-N-(3,4-dichlorophenyl)acetamide
CAS 701281-09-6C19H17Cl3N4OS
2-[5-[(4-Bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-N-phenylacetamide chemical structure, C19H19BrN4OS, CAS 701282-25-9
2-[5-[(4-Bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-N-phenylacetamide
CAS 701282-25-9C19H19BrN4OS
2-[5-[(4-Fluorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-N-(4-methylphenyl)acetamide chemical structure, C19H19FN4OS, CAS 708220-43-3
2-[5-[(4-Fluorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-N-(4-methylphenyl)acetamide
CAS 708220-43-3C19H19FN4OS
2-[5-[(4-Chlorophenyl)methylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]-N-(3-methoxyphenyl)acetamide chemical structure, C21H21ClN4O2S, CAS 708283-59-4
2-[5-[(4-Chlorophenyl)methylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]-N-(3-methoxyphenyl)acetamide
CAS 708283-59-4C21H21ClN4O2S
2-[5-[(4-Fluorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-N-(3-methoxyphenyl)acetamide chemical structure, C19H19FN4O2S, CAS 708995-18-0
2-[5-[(4-Fluorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-N-(3-methoxyphenyl)acetamide
CAS 708995-18-0C19H19FN4O2S
N-(3-Chloro-4-methylphenyl)-2-[5-[(2,4-dichlorophenyl)methylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]acetamide chemical structure, C21H19Cl3N4OS, CAS 713501-32-7
N-(3-Chloro-4-methylphenyl)-2-[5-[(2,4-dichlorophenyl)methylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]acetamide
CAS 713501-32-7C21H19Cl3N4OS
2-[5-[(3,4-Dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-N-(2-methylphenyl)acetamide chemical structure, C19H18Cl2N4OS, CAS 767325-53-1
2-[5-[(3,4-Dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-N-(2-methylphenyl)acetamide
CAS 767325-53-1C19H18Cl2N4OS
2-[5-[(3,4-Dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-N-(4-ethoxyphenyl)acetamide chemical structure, C21H22Cl2N4O2S, CAS 792943-46-5
2-[5-[(3,4-Dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-N-(4-ethoxyphenyl)acetamide
CAS 792943-46-5C21H22Cl2N4O2S
N-(3-Chloro-4-methylphenyl)-2-[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]acetamide chemical structure, C20H19Cl3N4OS, CAS 767325-55-3
N-(3-Chloro-4-methylphenyl)-2-[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]acetamide
CAS 767325-55-3C20H19Cl3N4OS
2-[5-[(2,4-Dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-N-(4-methoxyphenyl)acetamide chemical structure, C20H20Cl2N4O2S, CAS 767325-54-2
2-[5-[(2,4-Dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-N-(4-methoxyphenyl)acetamide
CAS 767325-54-2C20H20Cl2N4O2S
2-[4-Ethyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-N-phenylacetamide chemical structure, C19H19N5O3S, CAS 767326-21-6
2-[4-Ethyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-N-phenylacetamide
CAS 767326-21-6C19H19N5O3S
N-(3-Methoxyphenyl)-2-[4-methyl-5-[(3-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]acetamide chemical structure, C20H22N4O2S, CAS 839689-53-1
N-(3-Methoxyphenyl)-2-[4-methyl-5-[(3-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]acetamide
CAS 839689-53-1C20H22N4O2S
2-[4-Ethyl-5-[(3-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-N-phenylacetamide chemical structure, C20H22N4OS, CAS 839691-22-4
2-[4-Ethyl-5-[(3-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-N-phenylacetamide
CAS 839691-22-4C20H22N4OS
2-[4-Methyl-5-[(2-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-N-phenylacetamide chemical structure, C19H20N4OS, CAS 915884-78-5
2-[4-Methyl-5-[(2-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-N-phenylacetamide
CAS 915884-78-5C19H20N4OS