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Murcko scaffold

5-(Pyridin-3-yl)-1,2,4-oxadiazole scaffold

64 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
64
With full pages
5
Scaffold SMILES

c1cncc(-c2ncno2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(Pyridin-3-yl)-1,2,4-oxadiazole page
Murcko scaffold c1cncc(-c2ncno2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 64 chemicals

3-[3-(Chloromethyl)-1,2,4-oxadiazol-5-yl]-2-(methylthio)pyridine chemical structure, C9H8ClN3OS, CAS 252914-65-1
3-[3-(Chloromethyl)-1,2,4-oxadiazol-5-yl]-2-(methylthio)pyridine
CAS 252914-65-1C9H8ClN3OS
5-{3-[(tert-Butylsulphonyl)methyl]-1,2,4-oxadiazol-5-yl}-2-chloropyridine chemical structure, C12H14ClN3O3S, CAS 680216-16-4
5-{3-[(tert-Butylsulphonyl)methyl]-1,2,4-oxadiazol-5-yl}-2-chloropyridine
CAS 680216-16-4C12H14ClN3O3S
2-Chloro-3-(3-methyl-1,2,4-oxadiazol-5-yl)pyridine chemical structure, C8H6ClN3O, CAS 890095-56-4
2-Chloro-3-(3-methyl-1,2,4-oxadiazol-5-yl)pyridine
CAS 890095-56-4C8H6ClN3O
5-Pyridin-3-yl-[1,2,4]oxadiazol-3-ylamine chemical structure, C7H6N4O, CAS 73631-18-2
5-Pyridin-3-yl-[1,2,4]oxadiazol-3-ylamine
CAS 73631-18-2C7H6N4O
5-(Pyridin-3-yl)-1,2,4-oxadiazole chemical structure, C7H5N3O, CAS 128164-72-7
5-(Pyridin-3-yl)-1,2,4-oxadiazole
CAS 128164-72-7C7H5N3O
3-[3-(Chloromethyl)-1,2,4-oxadiazol-5-yl]pyridine chemical structure, C8H6ClN3O, CAS 926225-49-2
3-[3-(Chloromethyl)-1,2,4-oxadiazol-5-yl]pyridine
CAS 926225-49-2C8H6ClN3O
2-(5-(Pyridin-3-yl)-1,2,4-oxadiazol-3-yl)ethan-1-amine chemical structure, C9H10N4O, CAS 946745-15-9
2-(5-(Pyridin-3-yl)-1,2,4-oxadiazol-3-yl)ethan-1-amine
CAS 946745-15-9C9H10N4O
Ethyl 5-(pyridin-3-yl)-1,2,4-oxadiazole-3-carboxylate chemical structure, C10H9N3O3, CAS 151098-17-8
Ethyl 5-(pyridin-3-yl)-1,2,4-oxadiazole-3-carboxylate
CAS 151098-17-8C10H9N3O3
3-(3-Methyl-1,2,4-oxadiazol-5-yl)pyridine chemical structure, C8H7N3O, CAS 1455-85-2
3-(3-Methyl-1,2,4-oxadiazol-5-yl)pyridine
CAS 1455-85-2C8H7N3O
2-Chloro-3-(3-ethyl-1,2,4-oxadiazol-5-yl)pyridine chemical structure, C9H8ClN3O, CAS 937669-85-7
2-Chloro-3-(3-ethyl-1,2,4-oxadiazol-5-yl)pyridine
CAS 937669-85-7C9H8ClN3O
2-Chloro-3-(3-propyl-1,2,4-oxadiazol-5-yl)pyridine chemical structure, C10H10ClN3O, CAS 937696-64-5
2-Chloro-3-(3-propyl-1,2,4-oxadiazol-5-yl)pyridine
CAS 937696-64-5C10H10ClN3O
2-Chloro-3-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]pyridine chemical structure, C10H10ClN3O, CAS 937681-16-8
2-Chloro-3-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]pyridine
CAS 937681-16-8C10H10ClN3O
2-Chloro-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridine chemical structure, C8H6ClN3O, CAS 959240-62-1
2-Chloro-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridine
CAS 959240-62-1C8H6ClN3O
3-(5-(Pyridin-3-yl)-1,2,4-oxadiazol-3-yl)propanoic acid chemical structure, C10H9N3O3, CAS 1082503-17-0
3-(5-(Pyridin-3-yl)-1,2,4-oxadiazol-3-yl)propanoic acid
CAS 1082503-17-0C10H9N3O3
5-Pyridin-3-yl-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C8H5N3O3, CAS 1086380-42-8
5-Pyridin-3-yl-1,2,4-oxadiazole-3-carboxylic acid
CAS 1086380-42-8C8H5N3O3
3-Bromo-5-[3-(chloromethyl)-1,2,4-oxadiazol-5-yl]pyridine chemical structure, C8H5BrClN3O, CAS 1039335-76-6
3-Bromo-5-[3-(chloromethyl)-1,2,4-oxadiazol-5-yl]pyridine
CAS 1039335-76-6C8H5BrClN3O
2-Chloro-5-(3-propyl-1,2,4-oxadiazol-5-yl)pyridine chemical structure, C10H10ClN3O, CAS 1119396-03-0
2-Chloro-5-(3-propyl-1,2,4-oxadiazol-5-yl)pyridine
CAS 1119396-03-0C10H10ClN3O
2-Hydrazinyl-5-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]pyridine chemical structure, C10H13N5O, CAS 1255784-22-5
2-Hydrazinyl-5-[3-(propan-2-yl)-1,2,4-oxadiazol-5-yl]pyridine
CAS 1255784-22-5C10H13N5O
3-Bromo-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridine chemical structure, C8H6BrN3O, CAS 1283108-13-3
3-Bromo-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridine
CAS 1283108-13-3C8H6BrN3O
{[5-(3-Propyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]sulfanyl}acetic acid chemical structure, C12H13N3O3S, CAS 1325306-92-0
{[5-(3-Propyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]sulfanyl}acetic acid
CAS 1325306-92-0C12H13N3O3S
{[5-(3-Ethyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]sulfanyl}acetic acid chemical structure, C11H11N3O3S, CAS 1326942-68-0
{[5-(3-Ethyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]sulfanyl}acetic acid
CAS 1326942-68-0C11H11N3O3S
Ethyl {[5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]sulfanyl}acetate chemical structure, C12H13N3O3S, CAS 1326836-99-0
Ethyl {[5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl]sulfanyl}acetate
CAS 1326836-99-0C12H13N3O3S
2-Hydrazino-5-[3-(2-methoxyethyl)-1,2,4-oxadiazol-5-yl]pyridine chemical structure, C10H13N5O2, CAS 1325303-55-6
2-Hydrazino-5-[3-(2-methoxyethyl)-1,2,4-oxadiazol-5-yl]pyridine
CAS 1325303-55-6C10H13N5O2
3-Ethyl-5-(6-hydrazinylpyridin-3-yl)-1,2,4-oxadiazole chemical structure, C9H11N5O, CAS 1325303-72-7
3-Ethyl-5-(6-hydrazinylpyridin-3-yl)-1,2,4-oxadiazole
CAS 1325303-72-7C9H11N5O