Murcko scaffold
N-Phenyl-3-thiophenecarboxamide scaffold
165 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 165
- With full pages
- 18
Scaffold SMILES
O=C(Nc1ccccc1)c1ccsc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 165 chemicals
3-Thiophenecarboxamide, N-(4-methoxyphenyl)-5-nitro-
CAS 146795-26-8C12H10N2O4S
3-Thiophenecarboxamide, N-(3-methoxyphenyl)-5-nitro-
CAS 146795-27-9C12H10N2O4S
3-Thiophenecarboxamide, N-(2-methoxyphenyl)-5-nitro-
CAS 146795-28-0C12H10N2O4S
3-Thiophenecarboxamide, N-(4-methylphenyl)-5-nitro-
CAS 146795-29-1C12H10N2O3S
3-Thiophenecarboxamide, N-(3-methylphenyl)-5-nitro-
CAS 146795-30-4C12H10N2O3S
3-Thiophenecarboxamide, N-(2-methylphenyl)-5-nitro-
CAS 146795-31-5C12H10N2O3S
3-Thiophenecarboxamide, N-(3-ethylphenyl)-5-nitro-
CAS 146795-32-6C13H12N2O3S
3-Thiophenecarboxamide, N-(2-ethylphenyl)-5-nitro-
CAS 146795-33-7C13H12N2O3S
3-Thiophenecarboxamide, 5-nitro-N-phenyl-
CAS 146795-34-8C11H8N2O3S
N-(4-Fluorophenyl)-5-nitro-3-thiophenecarboxamide
CAS 146795-35-9C11H7FN2O3S
N-(3-Fluorophenyl)-5-nitro-3-thiophenecarboxamide
CAS 146795-36-0C11H7FN2O3S
N-(2-Fluorophenyl)-5-nitro-3-thiophenecarboxamide
CAS 146795-37-1C11H7FN2O3S
3-Thiophenecarboxamide, N-(4-chlorophenyl)-5-nitro-
CAS 146795-38-2C11H7ClN2O3S
3-Thiophenecarboxamide, N-(3-chlorophenyl)-5-nitro-
CAS 146795-39-3C11H7ClN2O3S
3-Thiophenecarboxamide, N-(2-chlorophenyl)-5-nitro-
CAS 146795-40-6C11H7ClN2O3S
3-Thiophenecarboxamide, N-(4-bromophenyl)-5-nitro-
CAS 146795-41-7C11H7BrN2O3S
3-Thiophenecarboxamide, N-(3-bromophenyl)-5-nitro-
CAS 146795-42-8C11H7BrN2O3S
3-Thiophenecarboxamide, N-(2-bromophenyl)-5-nitro-
CAS 146795-43-9C11H7BrN2O3S
3-Thiophenecarboxamide, 5-nitro-N-(4-nitrophenyl)-
CAS 146795-44-0C11H7N3O5S
3-Thiophenecarboxamide, 5-nitro-N-(3-nitrophenyl)-
CAS 146795-45-1C11H7N3O5S
3-Thiophenecarboxamide, 5-nitro-N-(2-nitrophenyl)-
CAS 146795-46-2C11H7N3O5S
3-Thiophenecarboxamide, N-methyl-5-nitro-N-phenyl-
CAS 146795-48-4C12H10N2O3S
3-Thiophenecarboxamide, N-(4-ethylphenyl)-5-nitro-
CAS 146818-20-4C13H12N2O3S
Benzoic acid, 2-chloro-5-(((2-methyl-3-thienyl)carbonyl)amino)-, 2-methyl-1-(1-methylethyl)propyl ester
CAS 191984-60-8C20H24ClNO3S
- N-(4-Methoxyphenyl)-3-thiophenecarboxamide64419-15-4C12H11NO2S
- Ethyl 5-amino-4-((3,4-dimethylphenyl)carbamoyl)-3-methylthiophene-2-carboxylate370868-74-9C17H20N2O3S
- 2-(Isobutyrylamino)-4,5-dimethyl-N-phenyl-3-thiophenecarboxamide333359-03-8C17H20N2O2S
- N-(4-Methoxyphenyl)-4,5-dimethyl-2-(2-methylpropanoylamino)thiophene-3-carboxamide333359-04-9C18H22N2O3S
- 2-Amino-N-phenylthiophene-3-carboxamide50273-33-1C11H10N2OS
- Ethyl 5-amino-4-((2-methoxyphenyl)carbamoyl)-3-methylthiophene-2-carboxylate354561-74-3C16H18N2O4S
- N-[4-Chloro-2-(trifluoromethyl)phenyl]-4-ethyl-5-methylthiophene-3-carboxamide438226-34-7C15H13ClF3NOS
- 2-Amino-4-ethyl-5-methyl-N-[3-(trifluoromethyl)phenyl]thiophene-3-carboxamide522596-59-4C15H15F3N2OS
- 2-(Butanoylamino)-N-(2-methoxyphenyl)-4,5-dimethylthiophene-3-carboxamide326610-94-0C18H22N2O3S
- N-Phenyl-3-thiophenecarboxamide55797-29-0C11H9NOS
- Ethyl 5-amino-3-methyl-4-(phenylcarbamoyl)thiophene-2-carboxylate765291-12-1C15H16N2O3S
- N-(2-Ethoxyphenyl)-4,5-dimethyl-3-thiophenecarboxamide774589-68-3C15H17NO2S
- N-(3-Nitrophenyl)-5-propylthiophene-3-carboxamide774590-07-7C14H14N2O3S
- N-(4-Fluoro-2-methylphenyl)-5-methylthiophene-3-carboxamide717858-87-2C13H12FNOS
- N-(2-Carbamoylphenyl)-4-ethyl-5-methyl-3-thiophenecarboxamide775299-15-5C15H16N2O2S
- 5-Ethyl-N-phenylthiophene-3-carboxamide775300-09-9C13H13NOS
- N-(2,4-Dichlorophenyl)-4-ethyl-5-methylthiophene-3-carboxamide775299-17-7C14H13Cl2NOS
- 2-Acetamido-N-(4-chlorophenyl)thiophene-3-carboxamide338750-39-3C13H11ClN2O2S
- 5-Methyl-N-[4-(methylsulfamoyl)phenyl]thiophene-3-carboxamide717872-87-2C13H14N2O3S2
- N-(4-tert-Butylphenyl)thiophene-3-carboxamide717827-11-7C15H17NOS
- 5-Methyl-N-(2-nitrophenyl)thiophene-3-carboxamide717855-28-2C12H10N2O3S
- 2-{4-[(5-Methyl-3-thienyl)carbonylamino]phenyl}acetic acid830342-32-0C14H13NO3S
- 4-[(5-Methyl-3-thienyl)carbonylamino]benzoic acid830342-43-3C13H11NO3S
- 2-Amino-N-(3-chlorophenyl)-4-ethyl-5-methylthiophene-3-carboxamide588714-51-6C14H15ClN2OS
Related scaffolds
Same ring framework with different atoms or bond orders
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O=C(Nc1ccccc1)c1cccs1150 chemicals
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c1ccc(OCc2ccco2)cc175 chemicals
O=S(=O)(Nc1nccs1)c1ccccc161 chemicals![Scaffold c1ccc(CSc2ncn[nH]2)cc1](/scaffold/IQQYSQRJFHUASD-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1cc[nH]n160 chemicals
O=C(Nc1cccs1)c1ccccc152 chemicals
O=C(Nc1ccccc1)C1CCCO150 chemicals
O=C(Nc1ccccc1)c1ccoc148 chemicals
c1ccc(CSc2nncs2)cc144 chemicals