CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 20 atoms

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
10
With full pages
9
Scaffold SMILES

O=C(NN=Cc1ccncc1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccncc1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-(2,4-Dimethoxyphenyl)-N'-[(E)-pyridin-4-ylmethylideneamino]oxamide chemical structure, C16H16N4O4, CAS 419545-62-3
N-(2,4-Dimethoxyphenyl)-N'-[(E)-pyridin-4-ylmethylideneamino]oxamide
CAS 419545-62-3C16H16N4O4
N-(4-Methylphenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide chemical structure, C15H14N4O2, CAS 352460-81-2
N-(4-Methylphenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide
CAS 352460-81-2C15H14N4O2
N-(4-Ethylphenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide chemical structure, C16H16N4O2, CAS 769146-49-8
N-(4-Ethylphenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide
CAS 769146-49-8C16H16N4O2
N-(4-Methoxyphenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide chemical structure, C15H14N4O3, CAS 352460-84-5
N-(4-Methoxyphenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide
CAS 352460-84-5C15H14N4O3
N-(3-Methoxyphenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide chemical structure, C15H14N4O3, CAS 352460-83-4
N-(3-Methoxyphenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide
CAS 352460-83-4C15H14N4O3
N-(2,5-Dimethylphenyl)-2-oxo-2-{(2E)-2-[1-(pyridin-4-yl)ethylidene]hydrazinyl}acetamide chemical structure, C17H18N4O2, CAS 848214-24-4
N-(2,5-Dimethylphenyl)-2-oxo-2-{(2E)-2-[1-(pyridin-4-yl)ethylidene]hydrazinyl}acetamide
CAS 848214-24-4C17H18N4O2
N-(3,4-Dichlorophenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide chemical structure, C14H10Cl2N4O2, CAS 477734-08-0
N-(3,4-Dichlorophenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide
CAS 477734-08-0C14H10Cl2N4O2
N-(2-Methoxyphenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide chemical structure, C15H14N4O3, CAS 477734-09-1
N-(2-Methoxyphenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide
CAS 477734-09-1C15H14N4O3
N-(2,3-Dichlorophenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide chemical structure, C14H10Cl2N4O2, CAS 477733-94-1
N-(2,3-Dichlorophenyl)-2-oxo-2-(2-(4-pyridinylmethylene)hydrazino)acetamide
CAS 477733-94-1C14H10Cl2N4O2
2-Oxo-N-phenyl-2-(2-(4-pyridinylmethylene)hydrazino)acetamide chemical structure, C14H12N4O2, CAS 765296-34-2
2-Oxo-N-phenyl-2-(2-(4-pyridinylmethylene)hydrazino)acetamide
CAS 765296-34-2C14H12N4O2