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Murcko scaffold

6-Benzylpyrimidine-2,4(1H,3H)-dione scaffold

51 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
51
With full pages
7
Scaffold SMILES

O=c1cc(Cc2ccccc2)[nH]c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Benzylpyrimidine-2,4(1H,3H)-dione page
Murcko scaffold O=c1cc(Cc2ccccc2)[nH]c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 51 chemicals

6-(3,5-Dimethylbenzyl)-1-(ethoxymethyl)-5-isopropyluracil chemical structure, C19H26N2O3, CAS 149950-61-8
6-(3,5-Dimethylbenzyl)-1-(ethoxymethyl)-5-isopropyluracil
CAS 149950-61-8C19H26N2O3
Emivirine chemical structure, C17H22N2O3, CAS 149950-60-7
Emivirine
CAS 149950-60-7C17H22N2O3
6-Benzylpyrimidine-2,4(1H,3H)-dione chemical structure, C11H10N2O2, CAS 13345-11-4
6-Benzylpyrimidine-2,4(1H,3H)-dione
CAS 13345-11-4C11H10N2O2
6-(4-Nitrobenzyl)pyrimidine-2,4(1H,3H)-dione chemical structure, C11H9N3O4, CAS 13345-15-8
6-(4-Nitrobenzyl)pyrimidine-2,4(1H,3H)-dione
CAS 13345-15-8C11H9N3O4
6-Benzyl-5-bromopyrimidine-2,4(1H,3H)-dione chemical structure, C11H9BrN2O2, CAS 13441-90-2
6-Benzyl-5-bromopyrimidine-2,4(1H,3H)-dione
CAS 13441-90-2C11H9BrN2O2
4-[(5-Bromo-2,4-dioxo-1H-pyrimidin-6-yl)methyl]benzenesulfonamide chemical structure, C11H10BrN3O4S, CAS 16290-63-4
4-[(5-Bromo-2,4-dioxo-1H-pyrimidin-6-yl)methyl]benzenesulfonamide
CAS 16290-63-4C11H10BrN3O4S
6-[(4-Amino-3-nitrophenyl)methyl]-5-bromo-1H-pyrimidine-2,4-dione chemical structure, C11H9BrN4O4, CAS 18469-49-3
6-[(4-Amino-3-nitrophenyl)methyl]-5-bromo-1H-pyrimidine-2,4-dione
CAS 18469-49-3C11H9BrN4O4
6-[(4-Amino-3-nitrophenyl)methyl]-1H-pyrimidine-2,4-dione chemical structure, C11H10N4O4, CAS 18364-63-1
6-[(4-Amino-3-nitrophenyl)methyl]-1H-pyrimidine-2,4-dione
CAS 18364-63-1C11H10N4O4
N-[4-[(2,4-Dioxo-1H-pyrimidin-6-yl)methyl]phenyl]acetamide chemical structure, C13H13N3O3, CAS 18364-61-9
N-[4-[(2,4-Dioxo-1H-pyrimidin-6-yl)methyl]phenyl]acetamide
CAS 18364-61-9C13H13N3O3
N-[4-[(5-Bromo-2,4-dioxo-1H-pyrimidin-6-yl)methyl]-2-nitrophenyl]acetamide chemical structure, C13H11BrN4O5, CAS 18364-65-3
N-[4-[(5-Bromo-2,4-dioxo-1H-pyrimidin-6-yl)methyl]-2-nitrophenyl]acetamide
CAS 18364-65-3C13H11BrN4O5
N-[4-[(5-Bromo-2,4-dioxo-1H-pyrimidin-6-yl)methyl]phenyl]acetamide chemical structure, C13H12BrN3O3, CAS 18364-66-4
N-[4-[(5-Bromo-2,4-dioxo-1H-pyrimidin-6-yl)methyl]phenyl]acetamide
CAS 18364-66-4C13H12BrN3O3
5-Bromo-6-[(4-nitrophenyl)methyl]-1H-pyrimidine-2,4-dione chemical structure, C11H8BrN3O4, CAS 13441-92-4
5-Bromo-6-[(4-nitrophenyl)methyl]-1H-pyrimidine-2,4-dione
CAS 13441-92-4C11H8BrN3O4
4-((2,6-Dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl)benzene-1-sulfonyl chloride chemical structure, C11H9ClN2O4S, CAS 16290-71-4
4-((2,6-Dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl)benzene-1-sulfonyl chloride
CAS 16290-71-4C11H9ClN2O4S
6-(4-Methylbenzyl)pyrimidine-2,4(1H,3H)-dione chemical structure, C12H12N2O2, CAS 19188-51-3
6-(4-Methylbenzyl)pyrimidine-2,4(1H,3H)-dione
CAS 19188-51-3C12H12N2O2
6-Benzyl-5-iodo-1H-pyrimidine-2,4-dione chemical structure, C11H9IN2O2, CAS 16290-64-5
6-Benzyl-5-iodo-1H-pyrimidine-2,4-dione
CAS 16290-64-5C11H9IN2O2
2,4(1H,3H)-Pyrimidinedione, 6-[(4-fluorophenyl)methyl]- chemical structure, C11H9FN2O2, CAS 18364-64-2
2,4(1H,3H)-Pyrimidinedione, 6-[(4-fluorophenyl)methyl]-
CAS 18364-64-2C11H9FN2O2
6-Benzyl-1-[2-[tert-butyl(dimethyl)silyl]oxyethoxymethyl]-5-ethyl-pyrimidine-2,4-dione chemical structure, C22H34N2O4Si, CAS 153656-00-9
6-Benzyl-1-[2-[tert-butyl(dimethyl)silyl]oxyethoxymethyl]-5-ethyl-pyrimidine-2,4-dione
CAS 153656-00-9C22H34N2O4Si
1-((2-Hydroxyethoxy)methyl)-6-(1-hydroxy-1-phenyl-methyl)thymine chemical structure, C15H18N2O5, CAS 131194-13-3
1-((2-Hydroxyethoxy)methyl)-6-(1-hydroxy-1-phenyl-methyl)thymine
CAS 131194-13-3C15H18N2O5
2,4(1H,3H)-Pyrimidinedione, 1-((2-hydroxyethoxy)methyl)-5-methyl-6-(phenylmethyl)- chemical structure, C15H18N2O4, CAS 131194-14-4
2,4(1H,3H)-Pyrimidinedione, 1-((2-hydroxyethoxy)methyl)-5-methyl-6-(phenylmethyl)-
CAS 131194-14-4C15H18N2O4
2,4(1H,3H)-Pyrimidinedione, 6-((3,5-dimethylphenyl)methyl)-5-ethyl-1-((2-hydroxyethoxy)methyl)- chemical structure, C18H24N2O4, CAS 136105-79-8
2,4(1H,3H)-Pyrimidinedione, 6-((3,5-dimethylphenyl)methyl)-5-ethyl-1-((2-hydroxyethoxy)methyl)-
CAS 136105-79-8C18H24N2O4
1-Ethoxymethyl-5-ethyl-6-(3,5-dimethylbenzyl)uracil chemical structure, C18H24N2O3, CAS 136160-30-0
1-Ethoxymethyl-5-ethyl-6-(3,5-dimethylbenzyl)uracil
CAS 136160-30-0C18H24N2O3
6-Benzyl-5-methylpyrimidine-2,4(1H,3H)-dione chemical structure, C12H12N2O2, CAS 153815-98-6
6-Benzyl-5-methylpyrimidine-2,4(1H,3H)-dione
CAS 153815-98-6C12H12N2O2
6-(3-Methylbenzyl)pyrimidine-2,4(1H,3H)-dione chemical structure, C12H12N2O2, CAS 160921-86-8
6-(3-Methylbenzyl)pyrimidine-2,4(1H,3H)-dione
CAS 160921-86-8C12H12N2O2
6-Benzyl-1-(ethoxymethyl)-5-ethyluracil chemical structure, C16H20N2O3, CAS 136160-29-7
6-Benzyl-1-(ethoxymethyl)-5-ethyluracil
CAS 136160-29-7C16H20N2O3