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Murcko scaffold

Ring system with 2 rings and 11 atoms

647 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
647
With full pages
25
Scaffold SMILES

c1cc(N2CCCC2)ncn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(N2CCCC2)ncn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 647 chemicals

5-Ethyl-4-methyl-6-(pyrrolidin-1-yl)pyrimidin-2-amine chemical structure, C11H18N4, CAS 424803-29-2
5-Ethyl-4-methyl-6-(pyrrolidin-1-yl)pyrimidin-2-amine
CAS 424803-29-2C11H18N4
4-Chloro-6-pyrrolidin-1-yl-pyrimidin-5-ylamine chemical structure, C8H11ClN4, CAS 626217-76-3
4-Chloro-6-pyrrolidin-1-yl-pyrimidin-5-ylamine
CAS 626217-76-3C8H11ClN4
4-Chloro-N-methyl-5-(methylsulfanyl)-6-(1-pyrrolidinyl)-2-pyrimidinamine chemical structure, C10H15ClN4S, CAS 400074-29-5
4-Chloro-N-methyl-5-(methylsulfanyl)-6-(1-pyrrolidinyl)-2-pyrimidinamine
CAS 400074-29-5C10H15ClN4S
4-(Methoxymethyl)-2-(methylsulfanyl)-6-(1-pyrrolidinyl)pyrimidine chemical structure, C11H17N3OS, CAS 338748-05-3
4-(Methoxymethyl)-2-(methylsulfanyl)-6-(1-pyrrolidinyl)pyrimidine
CAS 338748-05-3C11H17N3OS
4-Chloro-6-(pyrrolidin-1-yl)pyrimidin-2-amine chemical structure, C8H11ClN4, CAS 263276-45-5
4-Chloro-6-(pyrrolidin-1-yl)pyrimidin-2-amine
CAS 263276-45-5C8H11ClN4
4-Chloro-2-(methylthio)-6-(pyrrolidin-1-yl)pyrimidine chemical structure, C9H12ClN3S, CAS 339017-59-3
4-Chloro-2-(methylthio)-6-(pyrrolidin-1-yl)pyrimidine
CAS 339017-59-3C9H12ClN3S
Ethyl 2-(methylthio)-4-(1-pyrrolidinyl)-5-pyrimidinecarboxylate chemical structure, C12H17N3O2S, CAS 339019-53-3
Ethyl 2-(methylthio)-4-(1-pyrrolidinyl)-5-pyrimidinecarboxylate
CAS 339019-53-3C12H17N3O2S
N2-(3-(diethylamino)propyl)-5-nitro-6-(pyrrolidin-1-yl)pyrimidine-2,4-diamine chemical structure, C15H27N7O2, CAS 674297-49-5
N2-(3-(diethylamino)propyl)-5-nitro-6-(pyrrolidin-1-yl)pyrimidine-2,4-diamine
CAS 674297-49-5C15H27N7O2
2-Methyl-4-[(methylsulfanyl)methyl]-6-(1-pyrrolidinyl)pyrimidine chemical structure, C11H17N3S, CAS 338967-95-6
2-Methyl-4-[(methylsulfanyl)methyl]-6-(1-pyrrolidinyl)pyrimidine
CAS 338967-95-6C11H17N3S
4-Chloro-5-nitro-6-(pyrrolidin-1-yl)pyrimidine chemical structure, C8H9ClN4O2, CAS 25710-26-3
4-Chloro-5-nitro-6-(pyrrolidin-1-yl)pyrimidine
CAS 25710-26-3C8H9ClN4O2
5-Nitro-4-(pyrrolidin-1-yl)pyrimidin-2-amine chemical structure, C8H11N5O2, CAS 304692-63-5
5-Nitro-4-(pyrrolidin-1-yl)pyrimidin-2-amine
CAS 304692-63-5C8H11N5O2
4-(Pyrrolidin-1-yl)pyrimidine-2,6-diamine chemical structure, C8H13N5, CAS 113259-24-8
4-(Pyrrolidin-1-yl)pyrimidine-2,6-diamine
CAS 113259-24-8C8H13N5
2-Chloro-4-methyl-6-(pyrrolidin-1-yl)pyrimidine chemical structure, C9H12ClN3, CAS 425425-25-8
2-Chloro-4-methyl-6-(pyrrolidin-1-yl)pyrimidine
CAS 425425-25-8C9H12ClN3
4-Chloro-2-methylsulfanyl-6-pyrrolidin-1-yl-pyrimidine-5-carbaldehyde chemical structure, C10H12ClN3OS, CAS 445040-59-5
4-Chloro-2-methylsulfanyl-6-pyrrolidin-1-yl-pyrimidine-5-carbaldehyde
CAS 445040-59-5C10H12ClN3OS
2-Amino-4-(pyrrolidin-1-yl)-6-methylpyrimidine chemical structure, C9H14N4, CAS 723511-15-7
2-Amino-4-(pyrrolidin-1-yl)-6-methylpyrimidine
CAS 723511-15-7C9H14N4
2-Chloro-4-(pyrrolidin-1-yl)pyrimidine chemical structure, C8H10ClN3, CAS 35691-20-4
2-Chloro-4-(pyrrolidin-1-yl)pyrimidine
CAS 35691-20-4C8H10ClN3
4-Chloro-6-(pyrrolidin-1-yl)pyrimidine-5-carbonitrile chemical structure, C9H9ClN4, CAS 60025-12-9
4-Chloro-6-(pyrrolidin-1-yl)pyrimidine-5-carbonitrile
CAS 60025-12-9C9H9ClN4
4-Chloro-6-(pyrrolidin-1-yl)pyrimidine-5-carbaldehyde chemical structure, C9H10ClN3O, CAS 54503-92-3
4-Chloro-6-(pyrrolidin-1-yl)pyrimidine-5-carbaldehyde
CAS 54503-92-3C9H10ClN3O
(4-Pyrrolidin-1-ylpyrimidin-2-yl)methanol chemical structure, C9H13N3O, CAS 118779-78-5
(4-Pyrrolidin-1-ylpyrimidin-2-yl)methanol
CAS 118779-78-5C9H13N3O
2-(Chloromethyl)-4-(pyrrolidin-1-yl)pyrimidine chemical structure, C9H12ClN3, CAS 748733-00-8
2-(Chloromethyl)-4-(pyrrolidin-1-yl)pyrimidine
CAS 748733-00-8C9H12ClN3
4-(Methoxymethyl)-6-(pyrrolidin-1-yl)pyrimidine chemical structure, C10H15N3O, CAS 118779-97-8
4-(Methoxymethyl)-6-(pyrrolidin-1-yl)pyrimidine
CAS 118779-97-8C10H15N3O
2-Amino-4-chloro-6-(pyrrolidin-1-yl)pyrimidine-5-carbaldehyde chemical structure, C9H11ClN4O, CAS 155087-33-5
2-Amino-4-chloro-6-(pyrrolidin-1-yl)pyrimidine-5-carbaldehyde
CAS 155087-33-5C9H11ClN4O
2-Imino-6-methoxy-4-(pyrrolidin-1-yl)-1,2-dihydropyrimidine-5-carbaldehyde chemical structure, C10H14N4O2, CAS 930395-97-4
2-Imino-6-methoxy-4-(pyrrolidin-1-yl)-1,2-dihydropyrimidine-5-carbaldehyde
CAS 930395-97-4C10H14N4O2
2-Chloro-5-fluoro-4-(pyrrolidin-1-yl)pyrimidine chemical structure, C8H9ClFN3, CAS 923119-59-9
2-Chloro-5-fluoro-4-(pyrrolidin-1-yl)pyrimidine
CAS 923119-59-9C8H9ClFN3