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Murcko scaffold

Ring system with 4 rings and 19 atoms

98 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
98
With full pages
12
Scaffold SMILES

O=C1C=CC2C(=C1)CCC1C3CCCC3CC(=O)C21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CC2C(=C1)CCC1C3CCCC3CC(=O)C21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 98 chemicals

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione chemical structure, C21H26O5, CAS 1192475-75-4
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
CAS 1192475-75-4C21H26O5
Prednisone chemical structure, C21H26O5, CAS 53-03-2
Prednisone
CAS 53-03-2C21H26O5
Clobetasone butyrate chemical structure, C26H32ClFO5, CAS 25122-57-0
Clobetasone butyrate
CAS 25122-57-0C26H32ClFO5
Clobetasone chemical structure, C22H26ClFO4, CAS 54063-32-0
Clobetasone
CAS 54063-32-0C22H26ClFO4
Prednisone acetate chemical structure, C23H28O6, CAS 125-10-0
Prednisone acetate
CAS 125-10-0C23H28O6
Meprednisone acetate chemical structure, C24H30O6, CAS 1106-03-2
Meprednisone acetate
CAS 1106-03-2C24H30O6
6-Methylprednisone chemical structure, C22H28O5, CAS 91523-05-6
6-Methylprednisone
CAS 91523-05-6C22H28O5
21-Hydroxypregna-1,4-diene-3,11,20-trione chemical structure, C21H26O4, CAS 67067-81-6
21-Hydroxypregna-1,4-diene-3,11,20-trione
CAS 67067-81-6C21H26O4
Prednisone/proglumide chemical structure, C39H52N2O9, CAS 76448-27-6
Prednisone/proglumide
CAS 76448-27-6C39H52N2O9
20-Dihydroprednisone chemical structure, C21H28O5, CAS 2899-94-7
20-Dihydroprednisone
CAS 2899-94-7C21H28O5
Phenylbutazone mixture with prednisolone chemical structure, C40H46N2O7, CAS 8054-70-4
Phenylbutazone mixture with prednisolone
CAS 8054-70-4C40H46N2O7
Chloroprednisone acetate chemical structure, C23H27ClO6, CAS 14066-79-6
Chloroprednisone acetate
CAS 14066-79-6C23H27ClO6
Pregna-1,4-diene-3,11,20-trione chemical structure, C21H26O3, CAS 4368-11-0
Pregna-1,4-diene-3,11,20-trione
CAS 4368-11-0C21H26O3
[2-[(8S,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] N,N-bis(2-chloroethyl)carbamate chemical structure, C26H33Cl2NO6, CAS 2998-63-2
[2-[(8S,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] N,N-bis(2-chloroethyl)carbamate
CAS 2998-63-2C26H33Cl2NO6
17-Acetyl-10,13-dimethyl-7,8,9,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-3,11-dione chemical structure, C21H26O3, CAS 5039-32-7
17-Acetyl-10,13-dimethyl-7,8,9,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-3,11-dione
CAS 5039-32-7C21H26O3
Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxymethyl-, acetate chemical structure, C24H30O6, CAS 1323-57-5
Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxymethyl-, acetate
CAS 1323-57-5C24H30O6
Chloroprednisone chemical structure, C21H25ClO5, CAS 52080-57-6
Chloroprednisone
CAS 52080-57-6C21H25ClO5
Pregna-1,4-diene-3,11,20-trione, 21-(fluoro-18F)-17-hydroxy- chemical structure, C21H25FO4, CAS 110558-69-5
Pregna-1,4-diene-3,11,20-trione, 21-(fluoro-18F)-17-hydroxy-
CAS 110558-69-5C21H25FO4
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione 21-hexadecanoate chemical structure, C37H56O6, CAS 39007-81-3
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione 21-hexadecanoate
CAS 39007-81-3C37H56O6
Meprednisone chemical structure, C22H28O5, CAS 1247-42-3
Meprednisone
CAS 1247-42-3C22H28O5
Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxymethyl- chemical structure, C23H30O5, CAS 1323-45-1
Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxymethyl-
CAS 1323-45-1C23H30O5
Pregna-1,4-diene-3,11,20-trione, 21-(2,2-dimethyl-1-oxopropoxy)-17-hydroxy- chemical structure, C26H34O6, CAS 51192-49-5
Pregna-1,4-diene-3,11,20-trione, 21-(2,2-dimethyl-1-oxopropoxy)-17-hydroxy-
CAS 51192-49-5C26H34O6
17-Hydroxy-21-phosphonooxy-pregna-1,4-diene-3,11,20-trione chemical structure, C21H27O8P, CAS 57099-40-8
17-Hydroxy-21-phosphonooxy-pregna-1,4-diene-3,11,20-trione
CAS 57099-40-8C21H27O8P
Clobetasone 17-propionate chemical structure, C25H30ClFO5, CAS 25122-56-9
Clobetasone 17-propionate
CAS 25122-56-9C25H30ClFO5