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Murcko scaffold

Ring system with 3 rings and 20 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
4
With full pages
1
Scaffold SMILES

O=C(NNc1ccc2cn[nH]c2n1)Nc1ccncc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NNc1ccc2cn[nH]c2n1)Nc1ccncc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

Jte 013 chemical structure, C17H19Cl2N7O, CAS 383150-41-2
Jte 013
CAS 383150-41-2C17H19Cl2N7O
1-(3,5-Dichloropyridin-4-yl)-3-[(1,3-dimethyl-4-propylpyrazolo[3,4-b]pyridin-6-yl)amino]urea chemical structure, C17H19Cl2N7O, CAS 547756-93-4
1-(3,5-Dichloropyridin-4-yl)-3-[(1,3-dimethyl-4-propylpyrazolo[3,4-b]pyridin-6-yl)amino]urea
CAS 547756-93-4C17H19Cl2N7O
Hydrazinecarboxamide, N-(2-chloro-6-propoxy-4-pyridinyl)-2-(1,3-dimethyl-4-(1-methylethyl)-1H-pyrazolo(3,4-b)pyridin-6-yl)-2-(2-hydroxyethyl)- chemical structure, C22H30ClN7O3, CAS 1463913-43-0
Hydrazinecarboxamide, N-(2-chloro-6-propoxy-4-pyridinyl)-2-(1,3-dimethyl-4-(1-methylethyl)-1H-pyrazolo(3,4-b)pyridin-6-yl)-2-(2-hydroxyethyl)-
CAS 1463913-43-0C22H30ClN7O3
N-(2,6-Dichloro-4-pyridinyl)-2-[3-methyl-4-(1-methylethyl)-1-(2-propen-1-yl)-1H-pyrazolo[3,4-b]pyridin-6-yl]hydrazinecarboxamide chemical structure, C19H21Cl2N7O, CAS 1463912-49-3
N-(2,6-Dichloro-4-pyridinyl)-2-[3-methyl-4-(1-methylethyl)-1-(2-propen-1-yl)-1H-pyrazolo[3,4-b]pyridin-6-yl]hydrazinecarboxamide
CAS 1463912-49-3C19H21Cl2N7O