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Murcko scaffold

Ring system with 3 rings and 19 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
9
With full pages
5
Scaffold SMILES

O=C(Cc1ccccc1)Nc1ccc2c(c1)CCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)Nc1ccc2c(c1)CCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-(4-Chlorophenyl)-N-(2,3-dihydro-1H-inden-5-yl)acetamide chemical structure, C17H16ClNO, CAS 808189-91-5
2-(4-Chlorophenyl)-N-(2,3-dihydro-1H-inden-5-yl)acetamide
CAS 808189-91-5C17H16ClNO
N-(2,3-Dihydro-1H-inden-5-yl)-2-(4-fluorophenyl)acetamide chemical structure, C17H16FNO, CAS 803692-86-6
N-(2,3-Dihydro-1H-inden-5-yl)-2-(4-fluorophenyl)acetamide
CAS 803692-86-6C17H16FNO
N-(2,3-Dihydro-1H-inden-5-yl)-2-(3-methoxyphenyl)acetamide chemical structure, C18H19NO2, CAS 848582-19-4
N-(2,3-Dihydro-1H-inden-5-yl)-2-(3-methoxyphenyl)acetamide
CAS 848582-19-4C18H19NO2
N-(2,3-Dihydro-1H-inden-5-yl)-2-(4-hydroxyphenyl)acetamide chemical structure, C17H17NO2, CAS 321853-28-5
N-(2,3-Dihydro-1H-inden-5-yl)-2-(4-hydroxyphenyl)acetamide
CAS 321853-28-5C17H17NO2
N-(2,3-Dihydro-1H-inden-5-yl)-2-(3-fluorophenyl)acetamide chemical structure, C17H16FNO, CAS 746635-03-0
N-(2,3-Dihydro-1H-inden-5-yl)-2-(3-fluorophenyl)acetamide
CAS 746635-03-0C17H16FNO
N-(2,3-Dihydro-1H-inden-5-yl)-2-(2-fluorophenyl)acetamide chemical structure, C17H16FNO, CAS 847940-58-3
N-(2,3-Dihydro-1H-inden-5-yl)-2-(2-fluorophenyl)acetamide
CAS 847940-58-3C17H16FNO
2-(5-Acetyl-2-methoxyphenyl)-N-(2,3-dihydro-1H-inden-5-yl)acetamide chemical structure, C20H21NO3, CAS 877950-98-6
2-(5-Acetyl-2-methoxyphenyl)-N-(2,3-dihydro-1H-inden-5-yl)acetamide
CAS 877950-98-6C20H21NO3
N-(2,3-Dihydro-1H-inden-5-yl)-2-(4-nitrophenyl)acetamide chemical structure, C17H16N2O3, CAS 892719-07-2
N-(2,3-Dihydro-1H-inden-5-yl)-2-(4-nitrophenyl)acetamide
CAS 892719-07-2C17H16N2O3
2-Bromo-N-(2,3-dihydro-1H-inden-5-yl)-2-phenylacetamide chemical structure, C17H16BrNO, CAS 864932-47-8
2-Bromo-N-(2,3-dihydro-1H-inden-5-yl)-2-phenylacetamide
CAS 864932-47-8C17H16BrNO