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Murcko scaffold

4-(Pyrrolidin-2-yl)-1H-pyrazole scaffold

72 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
72
With full pages
5
Scaffold SMILES

c1n[nH]cc1C1CCCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyrrolidin-2-yl)-1H-pyrazole page
Murcko scaffold c1n[nH]cc1C1CCCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 72 chemicals

1-Methyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C8H13N3, CAS 1170640-87-5
1-Methyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1170640-87-5C8H13N3
1-Ethyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C9H15N3, CAS 1171607-85-4
1-Ethyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1171607-85-4C9H15N3
1-Methyl-4-[1-(2-methylprop-2-en-1-yl)pyrrolidin-2-yl]-1H-pyrazole chemical structure, C12H19N3, CAS 1333873-93-0
1-Methyl-4-[1-(2-methylprop-2-en-1-yl)pyrrolidin-2-yl]-1H-pyrazole
CAS 1333873-93-0C12H19N3
1,3,5-Trimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C10H17N3, CAS 1354953-49-3
1,3,5-Trimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1354953-49-3C10H17N3
N-(1-Cyano-1,2-dimethylpropyl)-2-[2-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-1-yl]acetamide chemical structure, C16H25N5O, CAS 1355604-37-3
N-(1-Cyano-1,2-dimethylpropyl)-2-[2-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-1-yl]acetamide
CAS 1355604-37-3C16H25N5O
4-(Pyrrolidin-2-yl)-1H-pyrazole chemical structure, C7H11N3, CAS 1211516-44-7
4-(Pyrrolidin-2-yl)-1H-pyrazole
CAS 1211516-44-7C7H11N3
1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-3-amine chemical structure, C9H16N4, CAS 1338984-26-1
1-Methyl-2-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-3-amine
CAS 1338984-26-1C9H16N4
1,5-Dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C9H15N3, CAS 1427380-52-6
1,5-Dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1427380-52-6C9H15N3
3,5-Dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C9H15N3, CAS 1367696-70-5
3,5-Dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1367696-70-5C9H15N3
1,3-Dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C9H15N3, CAS 1368379-70-7
1,3-Dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1368379-70-7C9H15N3
5-Chloro-3-methyl-1-(2-methylpropyl)-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C12H20ClN3, CAS 1394041-83-8
5-Chloro-3-methyl-1-(2-methylpropyl)-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1394041-83-8C12H20ClN3
5-Chloro-1,3-dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C9H14ClN3, CAS 1384427-69-3
5-Chloro-1,3-dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1384427-69-3C9H14ClN3
5-Methoxy-1,3-dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C10H17N3O, CAS 1376225-90-9
5-Methoxy-1,3-dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1376225-90-9C10H17N3O
N-(1-Cyano-1-methylethyl)-N-methyl-2-[2-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-1-yl]acetamide chemical structure, C15H23N5O, CAS 1376388-88-3
N-(1-Cyano-1-methylethyl)-N-methyl-2-[2-(1-methyl-1H-pyrazol-4-yl)pyrrolidin-1-yl]acetamide
CAS 1376388-88-3C15H23N5O
4-(Pyrrolidin-2-yl)-3-(trifluoromethyl)-1H-pyrazole chemical structure, C8H10F3N3, CAS 1534472-89-3
4-(Pyrrolidin-2-yl)-3-(trifluoromethyl)-1H-pyrazole
CAS 1534472-89-3C8H10F3N3
1-Methyl-4-(pyrrolidin-2-yl)-3-(trifluoromethyl)-1H-pyrazole chemical structure, C9H12F3N3, CAS 1519157-63-1
1-Methyl-4-(pyrrolidin-2-yl)-3-(trifluoromethyl)-1H-pyrazole
CAS 1519157-63-1C9H12F3N3
3-tert-Butyl-1-methyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C12H21N3, CAS 1545120-10-2
3-tert-Butyl-1-methyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1545120-10-2C12H21N3
3-tert-Butyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C11H19N3, CAS 1557299-91-8
3-tert-Butyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1557299-91-8C11H19N3
5-tert-Butyl-1-methyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C12H21N3, CAS 1546280-80-1
5-tert-Butyl-1-methyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1546280-80-1C12H21N3
tert-Butyl 2-(3,5-dimethyl-1H-pyrazol-4-yl)pyrrolidine-1-carboxylate chemical structure, C14H23N3O2, CAS 1706533-07-4
tert-Butyl 2-(3,5-dimethyl-1H-pyrazol-4-yl)pyrrolidine-1-carboxylate
CAS 1706533-07-4C14H23N3O2
1-Ethyl-3,5-dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C11H19N3, CAS 1710472-39-1
1-Ethyl-3,5-dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1710472-39-1C11H19N3
Ethyl 2-(3,5-dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazol-1-yl)acetate chemical structure, C13H21N3O2, CAS 1708268-95-4
Ethyl 2-(3,5-dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazol-1-yl)acetate
CAS 1708268-95-4C13H21N3O2
2-(3,5-Dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazol-1-yl)acetic acid chemical structure, C11H17N3O2, CAS 1707563-30-1
2-(3,5-Dimethyl-4-(pyrrolidin-2-yl)-1H-pyrazol-1-yl)acetic acid
CAS 1707563-30-1C11H17N3O2
1-(2-Methylpropyl)-4-(pyrrolidin-2-yl)-1H-pyrazole chemical structure, C11H19N3, CAS 1935401-06-1
1-(2-Methylpropyl)-4-(pyrrolidin-2-yl)-1H-pyrazole
CAS 1935401-06-1C11H19N3