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Murcko scaffold

Ring system with 5 rings and 29 atoms

16 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
29
Chemicals
16
With full pages
1
Scaffold SMILES

O=C(c1ccccc1)c1cc2c(-c3ccccc3)cc(-c3ccccc3)nc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1cc2c(-c3ccccc3)cc(-c3ccccc3)nc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

(3-Amino-4,6-diphenylthieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone chemical structure, C26H17ClN2OS, CAS 94360-99-3
(3-Amino-4,6-diphenylthieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone
CAS 94360-99-3C26H17ClN2OS
[3-Amino-4-(2-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl](phenyl)methanone chemical structure, C27H20N2O2S, CAS 313550-86-6
[3-Amino-4-(2-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl](phenyl)methanone
CAS 313550-86-6C27H20N2O2S
[3-Amino-4,6-bis(4-methoxyphenyl)thieno[2,3-b]pyridin-2-yl]-(3,4-dichlorophenyl)methanone chemical structure, C28H20Cl2N2O3S, CAS 303125-76-0
[3-Amino-4,6-bis(4-methoxyphenyl)thieno[2,3-b]pyridin-2-yl]-(3,4-dichlorophenyl)methanone
CAS 303125-76-0C28H20Cl2N2O3S
[3-Amino-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-(4-methoxyphenyl)methanone chemical structure, C28H22N2O3S, CAS 332867-78-4
[3-Amino-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-(4-methoxyphenyl)methanone
CAS 332867-78-4C28H22N2O3S
(3-Amino-4,6-diphenylthieno[2,3-b]pyridin-2-yl)(2-chlorophenyl)methanone chemical structure, C26H17ClN2OS, CAS 445384-53-2
(3-Amino-4,6-diphenylthieno[2,3-b]pyridin-2-yl)(2-chlorophenyl)methanone
CAS 445384-53-2C26H17ClN2OS
[3-Amino-6-(4-methoxyphenyl)-4-phenylthieno[2,3-b]pyridin-2-yl]-(2-chlorophenyl)methanone chemical structure, C27H19ClN2O2S, CAS 445384-56-5
[3-Amino-6-(4-methoxyphenyl)-4-phenylthieno[2,3-b]pyridin-2-yl]-(2-chlorophenyl)methanone
CAS 445384-56-5C27H19ClN2O2S
[3-Amino-6-(4-methoxyphenyl)-4-(4-methylphenyl)thieno[2,3-b]pyridin-2-yl]-phenylmethanone chemical structure, C28H22N2O2S, CAS 354793-34-3
[3-Amino-6-(4-methoxyphenyl)-4-(4-methylphenyl)thieno[2,3-b]pyridin-2-yl]-phenylmethanone
CAS 354793-34-3C28H22N2O2S
Methanone, (3-amino-4,6-diphenylthieno[2,3-b]pyridin-2-yl)phenyl- chemical structure, C26H18N2OS, CAS 58327-73-4
Methanone, (3-amino-4,6-diphenylthieno[2,3-b]pyridin-2-yl)phenyl-
CAS 58327-73-4C26H18N2OS
[3-Amino-4-(2-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-(4-chlorophenyl)methanone chemical structure, C27H19ClN2O2S, CAS 312758-14-8
[3-Amino-4-(2-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-(4-chlorophenyl)methanone
CAS 312758-14-8C27H19ClN2O2S
[3-Amino-4-(2-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-(4-methylphenyl)methanone chemical structure, C28H22N2O2S, CAS 342391-39-3
[3-Amino-4-(2-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-(4-methylphenyl)methanone
CAS 342391-39-3C28H22N2O2S
[3-Amino-6-(4-fluorophenyl)-4-phenylthieno[2,3-b]pyridin-2-yl](4-methylphenyl)methanone chemical structure, C27H19FN2OS, CAS 309286-01-9
[3-Amino-6-(4-fluorophenyl)-4-phenylthieno[2,3-b]pyridin-2-yl](4-methylphenyl)methanone
CAS 309286-01-9C27H19FN2OS
[3-Amino-4-(4-fluorophenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-phenylmethanone chemical structure, C26H17FN2OS, CAS 340808-10-8
[3-Amino-4-(4-fluorophenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-phenylmethanone
CAS 340808-10-8C26H17FN2OS
[3-Amino-4-(4-fluorophenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-(4-chlorophenyl)methanone chemical structure, C26H16ClFN2OS, CAS 316358-64-2
[3-Amino-4-(4-fluorophenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-(4-chlorophenyl)methanone
CAS 316358-64-2C26H16ClFN2OS
(3-Amino-4,6-bis(4-methoxyphenyl)thieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone chemical structure, C28H21ClN2O3S, CAS 671200-37-6
(3-Amino-4,6-bis(4-methoxyphenyl)thieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone
CAS 671200-37-6C28H21ClN2O3S
(3-Amino-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone chemical structure, C27H20N2O2S, CAS 126888-13-9
(3-Amino-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone
CAS 126888-13-9C27H20N2O2S
[3-Amino-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-(4-chlorophenyl)methanone chemical structure, C27H19ClN2O2S, CAS 332100-91-1
[3-Amino-4-(4-methoxyphenyl)-6-phenylthieno[2,3-b]pyridin-2-yl]-(4-chlorophenyl)methanone
CAS 332100-91-1C27H19ClN2O2S