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Murcko scaffold

Ring system with 5 rings and 28 atoms

4 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
28
Chemicals
4
With full pages
1
Scaffold SMILES

c1ncc(-c2nc(N3CCOCC3)c3sc(CN4CCNCC4)cc3n2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ncc(-c2nc(N3CCOCC3)c3sc(CN4CCNCC4)cc3n2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

Gne-477 chemical structure, C21H28N8O3S2, CAS 1032754-81-6
Gne-477
CAS 1032754-81-6C21H28N8O3S2
Apitolisib chemical structure, C23H30N8O3S, CAS 1032754-93-0
Apitolisib
CAS 1032754-93-0C23H30N8O3S
tert-Butyl 4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazine-1-carboxylate chemical structure, C25H34N8O3S, CAS 1032756-20-9
tert-Butyl 4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazine-1-carboxylate
CAS 1032756-20-9C25H34N8O3S
5-(7-Methyl-4-morpholino-6-(piperazin-1-ylmethyl)thieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine chemical structure, C20H26N8OS, CAS 1032756-62-9
5-(7-Methyl-4-morpholino-6-(piperazin-1-ylmethyl)thieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine
CAS 1032756-62-9C20H26N8OS