CompoundList
Sign in
Murcko scaffold

5-(Thiophen-2-yl)-4H-1,2,4-triazole-3-thiol scaffold

30 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
30
With full pages
8
Scaffold SMILES

S=c1[nH]nc(-c2cccs2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(Thiophen-2-yl)-4H-1,2,4-triazole-3-thiol page
Murcko scaffold S=c1[nH]nc(-c2cccs2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

4-(Prop-2-en-1-yl)-5-(thiophen-2-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C9H9N3S2, CAS 187795-50-2
4-(Prop-2-en-1-yl)-5-(thiophen-2-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS 187795-50-2C9H9N3S2
5-(Thiophen-2-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C6H5N3S2, CAS 68744-68-3
5-(Thiophen-2-yl)-4H-1,2,4-triazole-3-thiol
CAS 68744-68-3C6H5N3S2
4-Methyl-5-(thiophen-2-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C7H7N3S2, CAS 68744-66-1
4-Methyl-5-(thiophen-2-yl)-4H-1,2,4-triazole-3-thiol
CAS 68744-66-1C7H7N3S2
4-Ethyl-5-thiophen-2-yl-4H-[1,2,4]triazole-3-thiol chemical structure, C8H9N3S2, CAS 337473-17-3
4-Ethyl-5-thiophen-2-yl-4H-[1,2,4]triazole-3-thiol
CAS 337473-17-3C8H9N3S2
4-Amino-5-(thiophen-2-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C6H6N4S2, CAS 61019-27-0
4-Amino-5-(thiophen-2-yl)-4H-1,2,4-triazole-3-thiol
CAS 61019-27-0C6H6N4S2
4-Allyl-5-(3-methyl-2-thienyl)-4H-1,2,4-triazol-3-yl hydrosulfide chemical structure, C10H11N3S2, CAS 522597-59-7
4-Allyl-5-(3-methyl-2-thienyl)-4H-1,2,4-triazol-3-yl hydrosulfide
CAS 522597-59-7C10H11N3S2
4-Isobutyl-5-(3-methyl-2-thienyl)-4H-1,2,4-triazol-3-yl hydrosulfide chemical structure, C11H15N3S2, CAS 438232-73-6
4-Isobutyl-5-(3-methyl-2-thienyl)-4H-1,2,4-triazol-3-yl hydrosulfide
CAS 438232-73-6C11H15N3S2
4-Butyl-3-(3-methyl-2-thiophenyl)-1H-1,2,4-triazole-5-thione chemical structure, C11H15N3S2, CAS 438231-48-2
4-Butyl-3-(3-methyl-2-thiophenyl)-1H-1,2,4-triazole-5-thione
CAS 438231-48-2C11H15N3S2
4-Hexyl-3-thiophen-2-yl-1H-1,2,4-triazole-5-thione chemical structure, C12H17N3S2, CAS 522628-54-2
4-Hexyl-3-thiophen-2-yl-1H-1,2,4-triazole-5-thione
CAS 522628-54-2C12H17N3S2
4-Isopropyl-5-thien-2-yl-4H-1,2,4-triazole-3-thiol chemical structure, C9H11N3S2, CAS 667412-77-3
4-Isopropyl-5-thien-2-yl-4H-1,2,4-triazole-3-thiol
CAS 667412-77-3C9H11N3S2
4-Methyl-3-(5-methylthiophen-2-yl)-1H-1,2,4-triazole-5-thione chemical structure, C8H9N3S2, CAS 588687-46-1
4-Methyl-3-(5-methylthiophen-2-yl)-1H-1,2,4-triazole-5-thione
CAS 588687-46-1C8H9N3S2
5-(4-Bromothiophen-2-yl)-4-methyl-4H-1,2,4-triazole-3-thiol chemical structure, C7H6BrN3S2, CAS 828274-88-0
5-(4-Bromothiophen-2-yl)-4-methyl-4H-1,2,4-triazole-3-thiol
CAS 828274-88-0C7H6BrN3S2
5-(4,5-Dibromothiophen-2-yl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C7H5Br2N3S2, CAS 828274-97-1
5-(4,5-Dibromothiophen-2-yl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS 828274-97-1C7H5Br2N3S2
5-(4,5-Dibromothiophen-2-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol chemical structure, C8H7Br2N3S2, CAS 828275-81-6
5-(4,5-Dibromothiophen-2-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol
CAS 828275-81-6C8H7Br2N3S2
5-(4-Bromothiophen-2-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol chemical structure, C8H8BrN3S2, CAS 828276-13-7
5-(4-Bromothiophen-2-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol
CAS 828276-13-7C8H8BrN3S2
5-(4-Bromo-5-ethylthiophen-2-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol chemical structure, C10H12BrN3S2, CAS 828277-47-0
5-(4-Bromo-5-ethylthiophen-2-yl)-4-ethyl-4H-1,2,4-triazole-3-thiol
CAS 828277-47-0C10H12BrN3S2
2-[3-Sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]acetic acid chemical structure, C8H7N3O2S2, CAS 660417-26-5
2-[3-Sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]acetic acid
CAS 660417-26-5C8H7N3O2S2
2-(3-Mercapto-5-thien-2-yl-4H-1,2,4-triazol-4-yl)propanoic acid chemical structure, C9H9N3O2S2, CAS 854137-71-6
2-(3-Mercapto-5-thien-2-yl-4H-1,2,4-triazol-4-yl)propanoic acid
CAS 854137-71-6C9H9N3O2S2
3-[3-Sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]propanoic acid chemical structure, C9H9N3O2S2, CAS 854137-70-5
3-[3-Sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]propanoic acid
CAS 854137-70-5C9H9N3O2S2
4-Propyl-5-thien-2-yl-4H-1,2,4-triazole-3-thiol chemical structure, C9H11N3S2, CAS 451501-84-1
4-Propyl-5-thien-2-yl-4H-1,2,4-triazole-3-thiol
CAS 451501-84-1C9H11N3S2
(2S)-2-[3-Sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]propanoic acid chemical structure, C9H9N3O2S2, CAS 1212233-42-5
(2S)-2-[3-Sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]propanoic acid
CAS 1212233-42-5C9H9N3O2S2
3-Methyl-2-[3-sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]butanoic acid chemical structure, C11H13N3O2S2, CAS 869472-72-0
3-Methyl-2-[3-sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]butanoic acid
CAS 869472-72-0C11H13N3O2S2
3-[3-Sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]propanamide chemical structure, C9H10N4OS2, CAS 929972-33-8
3-[3-Sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]propanamide
CAS 929972-33-8C9H10N4OS2
2-[3-Sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]acetamide chemical structure, C8H8N4OS2, CAS 929972-36-1
2-[3-Sulfanyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-yl]acetamide
CAS 929972-36-1C8H8N4OS2