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Murcko scaffold

N-(Thiophen-2-ylmethyl)benzamide scaffold

95 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
95
With full pages
10
Scaffold SMILES

O=C(NCc1cccs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(Thiophen-2-ylmethyl)benzamide page
Murcko scaffold O=C(NCc1cccs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 95 chemicals

4-Methoxy-N-(thiophen-2-ylmethyl)benzamide chemical structure, C13H13NO2S, CAS 85797-10-0
4-Methoxy-N-(thiophen-2-ylmethyl)benzamide
CAS 85797-10-0C13H13NO2S
3,4,5-Trimethoxy-N-(2-thienylmethyl)benzamide chemical structure, C15H17NO4S, CAS 501002-77-3
3,4,5-Trimethoxy-N-(2-thienylmethyl)benzamide
CAS 501002-77-3C15H17NO4S
N-(2-Thienylmethyl)-2-[(2,2,2-trifluoroacetyl)amino]benzenecarboxamide chemical structure, C14H11F3N2O2S, CAS 329699-44-7
N-(2-Thienylmethyl)-2-[(2,2,2-trifluoroacetyl)amino]benzenecarboxamide
CAS 329699-44-7C14H11F3N2O2S
5-Methyl-N-(2-thienylmethyl)-2-[(2,2,2-trifluoroacetyl)amino]benzenecarboxamide chemical structure, C15H13F3N2O2S, CAS 329700-01-8
5-Methyl-N-(2-thienylmethyl)-2-[(2,2,2-trifluoroacetyl)amino]benzenecarboxamide
CAS 329700-01-8C15H13F3N2O2S
4-Chloro-N-(thiophen-2-ylmethyl)benzamide chemical structure, C12H10ClNOS, CAS 332082-86-7
4-Chloro-N-(thiophen-2-ylmethyl)benzamide
CAS 332082-86-7C12H10ClNOS
N-(Thiophen-2-ylmethyl)benzamide chemical structure, C12H11NOS, CAS 4595-96-4
N-(Thiophen-2-ylmethyl)benzamide
CAS 4595-96-4C12H11NOS
4-Fluoro-N-(2-thienylmethyl)benzamide chemical structure, C12H10FNOS, CAS 347321-80-6
4-Fluoro-N-(2-thienylmethyl)benzamide
CAS 347321-80-6C12H10FNOS
3,5-Dimethoxy-N-(thiophen-2-ylmethyl)benzamide chemical structure, C14H15NO3S, CAS 438530-48-4
3,5-Dimethoxy-N-(thiophen-2-ylmethyl)benzamide
CAS 438530-48-4C14H15NO3S
3-Fluoro-N-(2-thienylmethyl)benzamide chemical structure, C12H10FNOS, CAS 545440-49-1
3-Fluoro-N-(2-thienylmethyl)benzamide
CAS 545440-49-1C12H10FNOS
2-Methoxy-N-(2-thienylmethyl)benzamide chemical structure, C13H13NO2S, CAS 546106-24-5
2-Methoxy-N-(2-thienylmethyl)benzamide
CAS 546106-24-5C13H13NO2S
3,4,5-Triethoxy-N-(2-thienylmethyl)benzamide chemical structure, C18H23NO4S, CAS 546075-33-6
3,4,5-Triethoxy-N-(2-thienylmethyl)benzamide
CAS 546075-33-6C18H23NO4S
3-Chloro-4-nitro-N-(thiophen-2-ylmethyl)benzamide chemical structure, C12H9ClN2O3S, CAS 546120-34-7
3-Chloro-4-nitro-N-(thiophen-2-ylmethyl)benzamide
CAS 546120-34-7C12H9ClN2O3S
4-Nitro-N-(thiophen-2-ylmethyl)benzamide chemical structure, C12H10N2O3S, CAS 546068-26-2
4-Nitro-N-(thiophen-2-ylmethyl)benzamide
CAS 546068-26-2C12H10N2O3S
2-Chloro-5-nitro-N-(thiophen-2-ylmethyl)benzamide chemical structure, C12H9ClN2O3S, CAS 546106-55-2
2-Chloro-5-nitro-N-(thiophen-2-ylmethyl)benzamide
CAS 546106-55-2C12H9ClN2O3S
4-tert-Butyl-N-(thiophen-2-ylmethyl)benzamide chemical structure, C16H19NOS, CAS 546072-25-7
4-tert-Butyl-N-(thiophen-2-ylmethyl)benzamide
CAS 546072-25-7C16H19NOS
3,4-Diethoxy-N-(2-thienylmethyl)benzamide chemical structure, C16H19NO3S, CAS 351157-84-1
3,4-Diethoxy-N-(2-thienylmethyl)benzamide
CAS 351157-84-1C16H19NO3S
3-Bromo-N-(thiophen-2-ylmethyl)benzamide chemical structure, C12H10BrNOS, CAS 546067-90-7
3-Bromo-N-(thiophen-2-ylmethyl)benzamide
CAS 546067-90-7C12H10BrNOS
3-Nitro-N-(thiophen-2-ylmethyl)benzamide chemical structure, C12H10N2O3S, CAS 547703-69-5
3-Nitro-N-(thiophen-2-ylmethyl)benzamide
CAS 547703-69-5C12H10N2O3S
3-Methyl-N-(thiophen-2-ylmethyl)benzamide chemical structure, C13H13NOS, CAS 438475-03-7
3-Methyl-N-(thiophen-2-ylmethyl)benzamide
CAS 438475-03-7C13H13NOS
4-Amino-N-(thiophen-2-ylmethyl)benzamide chemical structure, C12H12N2OS, CAS 436095-49-7
4-Amino-N-(thiophen-2-ylmethyl)benzamide
CAS 436095-49-7C12H12N2OS
4-Chloro-2-nitro-N-(thiophen-2-ylmethyl)benzamide chemical structure, C12H9ClN2O3S, CAS 546120-26-7
4-Chloro-2-nitro-N-(thiophen-2-ylmethyl)benzamide
CAS 546120-26-7C12H9ClN2O3S
3,5-Dinitro-N-(thiophen-2-ylmethyl)benzamide chemical structure, C12H9N3O5S, CAS 445253-71-4
3,5-Dinitro-N-(thiophen-2-ylmethyl)benzamide
CAS 445253-71-4C12H9N3O5S
2,3,4,5,6-Pentafluoro-N-(thiophen-2-ylmethyl)benzamide chemical structure, C12H6F5NOS, CAS 547698-04-4
2,3,4,5,6-Pentafluoro-N-(thiophen-2-ylmethyl)benzamide
CAS 547698-04-4C12H6F5NOS
3-Iodo-N-(thiophen-2-ylmethyl)benzamide chemical structure, C12H10INOS, CAS 783318-39-8
3-Iodo-N-(thiophen-2-ylmethyl)benzamide
CAS 783318-39-8C12H10INOS