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Murcko scaffold

4-(1,3,4-Oxadiazol-2-yl)piperidine scaffold

59 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
59
With full pages
4
Scaffold SMILES

c1nnc(C2CCNCC2)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(1,3,4-Oxadiazol-2-yl)piperidine page
Murcko scaffold c1nnc(C2CCNCC2)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine chemical structure, C8H13N3O, CAS 161609-79-6
4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine
CAS 161609-79-6C8H13N3O
1-Boc-4-(5-methyl-1,3,4-oxadiazol-2-yl)piperidine chemical structure, C13H21N3O3, CAS 280110-69-2
1-Boc-4-(5-methyl-1,3,4-oxadiazol-2-yl)piperidine
CAS 280110-69-2C13H21N3O3
4-(5-Ethyl-1,3,4-oxadiazol-2-yl)piperidine chemical structure, C9H15N3O, CAS 773841-46-6
4-(5-Ethyl-1,3,4-oxadiazol-2-yl)piperidine
CAS 773841-46-6C9H15N3O
tert-Butyl 4-(5-(chloromethyl)-1,3,4-oxadiazol-2-yl)piperidine-1-carboxylate chemical structure, C13H20ClN3O3, CAS 685828-39-1
tert-Butyl 4-(5-(chloromethyl)-1,3,4-oxadiazol-2-yl)piperidine-1-carboxylate
CAS 685828-39-1C13H20ClN3O3
2-Methyl-5-(piperidin-4-yl)-1,3,4-oxadiazole hydrochloride chemical structure, C8H14ClN3O, CAS 280110-76-1
2-Methyl-5-(piperidin-4-yl)-1,3,4-oxadiazole hydrochloride
CAS 280110-76-1C8H14ClN3O
4-(1,3,4-Oxadiazol-2-yl)piperidine chemical structure, C7H11N3O, CAS 1082413-19-1
4-(1,3,4-Oxadiazol-2-yl)piperidine
CAS 1082413-19-1C7H11N3O
4-[5-(Propan-2-yl)-1,3,4-oxadiazol-2-yl]piperidine chemical structure, C10H17N3O, CAS 1082899-74-8
4-[5-(Propan-2-yl)-1,3,4-oxadiazol-2-yl]piperidine
CAS 1082899-74-8C10H17N3O
4-(5-Isobutyl-[1,3,4]oxadiazol-2-yl)-piperidine chemical structure, C11H19N3O, CAS 1082855-56-8
4-(5-Isobutyl-[1,3,4]oxadiazol-2-yl)-piperidine
CAS 1082855-56-8C11H19N3O
4-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)piperidine chemical structure, C11H19N3O, CAS 1082828-64-5
4-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)piperidine
CAS 1082828-64-5C11H19N3O
5-(Piperidin-4-yl)-1,3,4-oxadiazol-2-amine chemical structure, C7H12N4O, CAS 1118787-76-0
5-(Piperidin-4-yl)-1,3,4-oxadiazol-2-amine
CAS 1118787-76-0C7H12N4O
2-(1-(Butylsulfonyl)piperidin-4-yl)-5-isopropyl-1,3,4-oxadiazole chemical structure, C14H25N3O3S, CAS 1170393-64-2
2-(1-(Butylsulfonyl)piperidin-4-yl)-5-isopropyl-1,3,4-oxadiazole
CAS 1170393-64-2C14H25N3O3S
2-Isopropyl-5-(1-(propylsulfonyl)piperidin-4-yl)-1,3,4-oxadiazole chemical structure, C13H23N3O3S, CAS 1172054-96-4
2-Isopropyl-5-(1-(propylsulfonyl)piperidin-4-yl)-1,3,4-oxadiazole
CAS 1172054-96-4C13H23N3O3S
N-Isopropyl-4-(5-isopropyl-1,3,4-oxadiazol-2-yl)piperidine-1-carboxamide chemical structure, C14H24N4O2, CAS 1171225-79-8
N-Isopropyl-4-(5-isopropyl-1,3,4-oxadiazol-2-yl)piperidine-1-carboxamide
CAS 1171225-79-8C14H24N4O2
N-tert-Butyl-4-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]piperidine-1-carboxamide chemical structure, C15H26N4O2, CAS 1172926-74-7
N-tert-Butyl-4-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]piperidine-1-carboxamide
CAS 1172926-74-7C15H26N4O2
5-(1-Methylpiperidin-4-yl)-1,3,4-oxadiazol-2-amine chemical structure, C8H14N4O, CAS 7659-03-2
5-(1-Methylpiperidin-4-yl)-1,3,4-oxadiazol-2-amine
CAS 7659-03-2C8H14N4O
4-(5-Isopropyl-1,3,4-oxadiazol-2-yl)-N,N-dimethylpiperidine-1-sulfonamide chemical structure, C12H22N4O3S, CAS 1211689-02-9
4-(5-Isopropyl-1,3,4-oxadiazol-2-yl)-N,N-dimethylpiperidine-1-sulfonamide
CAS 1211689-02-9C12H22N4O3S
5-(Piperidin-4-yl)-1,3,4-oxadiazol-2-amine hydrochloride chemical structure, C7H13ClN4O, CAS 1209652-34-5
5-(Piperidin-4-yl)-1,3,4-oxadiazol-2-amine hydrochloride
CAS 1209652-34-5C7H13ClN4O
N,N-Dimethyl-1-(5-(piperidin-4-yl)-1,3,4-oxadiazol-2-yl)methanamine chemical structure, C10H18N4O, CAS 949100-23-6
N,N-Dimethyl-1-(5-(piperidin-4-yl)-1,3,4-oxadiazol-2-yl)methanamine
CAS 949100-23-6C10H18N4O
Ethyl 2-(2-{4-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]piperidin-1-yl}acetamido)acetate chemical structure, C16H26N4O4, CAS 1251706-26-9
Ethyl 2-(2-{4-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]piperidin-1-yl}acetamido)acetate
CAS 1251706-26-9C16H26N4O4
4-(5-Ethyl-1,3,4-oxadiazol-2-yl)piperidine hydrochloride chemical structure, C9H16ClN3O, CAS 1365965-90-7
4-(5-Ethyl-1,3,4-oxadiazol-2-yl)piperidine hydrochloride
CAS 1365965-90-7C9H16ClN3O
4-Methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)piperidine hydrochloride chemical structure, C9H16ClN3O, CAS 1332530-91-2
4-Methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)piperidine hydrochloride
CAS 1332530-91-2C9H16ClN3O
2-Methyl-5-(piperidin-4-yl)-1,3,4-oxadiazole 2,2,2-trifluoroacetate chemical structure, C10H14F3N3O3, CAS 1332530-14-9
2-Methyl-5-(piperidin-4-yl)-1,3,4-oxadiazole 2,2,2-trifluoroacetate
CAS 1332530-14-9C10H14F3N3O3
4-[5-(Methoxymethyl)-1,3,4-oxadiazol-2-yl]piperidine chemical structure, C9H15N3O2, CAS 1361112-48-2
4-[5-(Methoxymethyl)-1,3,4-oxadiazol-2-yl]piperidine
CAS 1361112-48-2C9H15N3O2
4-(5-Hydroxymethyl-[1,3,4]oxadiazol-2-yl)piperidine-1-carboxylic acid tert-butyl ester chemical structure, C13H21N3O4, CAS 859154-72-6
4-(5-Hydroxymethyl-[1,3,4]oxadiazol-2-yl)piperidine-1-carboxylic acid tert-butyl ester
CAS 859154-72-6C13H21N3O4