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Murcko scaffold

Pyrido(2,3-b)pyrazine scaffold

146 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
146
With full pages
21
Scaffold SMILES

c1cnc2nccnc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrido(2,3-b)pyrazine page
Murcko scaffold c1cnc2nccnc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 146 chemicals

Pyrido(2,3-b)pyrazine chemical structure, C7H5N3, CAS 322-46-3
Pyrido(2,3-b)pyrazine
CAS 322-46-3C7H5N3
2,3-Dimethylpyrido[2,3-b]pyrazin-6-amine chemical structure, C9H10N4, CAS 195045-42-2
2,3-Dimethylpyrido[2,3-b]pyrazin-6-amine
CAS 195045-42-2C9H10N4
Pyrido[2,3-b]pyrazin-6-amine chemical structure, C7H6N4, CAS 65257-68-3
Pyrido[2,3-b]pyrazin-6-amine
CAS 65257-68-3C7H6N4
2,3-Dimethylpyrido[2,3-b]pyrazine chemical structure, C9H9N3, CAS 7154-32-7
2,3-Dimethylpyrido[2,3-b]pyrazine
CAS 7154-32-7C9H9N3
Ethyl (8-amino-2-methylpyrido[2,3-b]pyrazin-6-yl)carbamate chemical structure, C11H13N5O2, CAS 6497-84-3
Ethyl (8-amino-2-methylpyrido[2,3-b]pyrazin-6-yl)carbamate
CAS 6497-84-3C11H13N5O2
Ethyl 8-[[4-[diethylamino]-1-methylbutyl]amino]pyrido[2,3-b]pyrazine-6-carbamate chemical structure, C19H30N6O2, CAS 19270-44-1
Ethyl 8-[[4-[diethylamino]-1-methylbutyl]amino]pyrido[2,3-b]pyrazine-6-carbamate
CAS 19270-44-1C19H30N6O2
Ethyl (8-((5-(diethylamino)pentan-2-yl)amino)-3-methylpyrido[2,3-b]pyrazin-6-yl)carbamate chemical structure, C20H32N6O2, CAS 21271-70-5
Ethyl (8-((5-(diethylamino)pentan-2-yl)amino)-3-methylpyrido[2,3-b]pyrazin-6-yl)carbamate
CAS 21271-70-5C20H32N6O2
2-Methylpyrido[2,3-b]pyrazine-6,8-diamine chemical structure, C8H9N5, CAS 74023-41-9
2-Methylpyrido[2,3-b]pyrazine-6,8-diamine
CAS 74023-41-9C8H9N5
3-Methylpyrido[2,3-b]pyrazine-6,8-diamine chemical structure, C8H9N5, CAS 740021-51-6
3-Methylpyrido[2,3-b]pyrazine-6,8-diamine
CAS 740021-51-6C8H9N5
6-Chloropyrido[2,3-b]pyrazine chemical structure, C7H4ClN3, CAS 68236-03-3
6-Chloropyrido[2,3-b]pyrazine
CAS 68236-03-3C7H4ClN3
7-Bromo-2,3-dimethylpyrido(2,3-b)pyrazine chemical structure, C9H8BrN3, CAS 52333-43-4
7-Bromo-2,3-dimethylpyrido(2,3-b)pyrazine
CAS 52333-43-4C9H8BrN3
7-Bromopyrido[2,3-b]pyrazine-6-carboxylic acid chemical structure, C8H4BrN3O2, CAS 887206-72-6
7-Bromopyrido[2,3-b]pyrazine-6-carboxylic acid
CAS 887206-72-6C8H4BrN3O2
7-Bromopyrido[2,3-b]pyrazine-8-carboxylic acid chemical structure, C8H4BrN3O2, CAS 887206-76-0
7-Bromopyrido[2,3-b]pyrazine-8-carboxylic acid
CAS 887206-76-0C8H4BrN3O2
7-Bromopyrido[2,3-b]pyrazine chemical structure, C7H4BrN3, CAS 52333-42-3
7-Bromopyrido[2,3-b]pyrazine
CAS 52333-42-3C7H4BrN3
Pyrido[2,3-b]pyrazine-6-carboxylic acid chemical structure, C8H5N3O2, CAS 893723-33-6
Pyrido[2,3-b]pyrazine-6-carboxylic acid
CAS 893723-33-6C8H5N3O2
Pyrido[2,3-b]pyrazine-8-carboxylic acid chemical structure, C8H5N3O2, CAS 893723-38-1
Pyrido[2,3-b]pyrazine-8-carboxylic acid
CAS 893723-38-1C8H5N3O2
Pyrido(2,3-b)pyrazine-7-carboxylic acid chemical structure, C8H5N3O2, CAS 893723-49-4
Pyrido(2,3-b)pyrazine-7-carboxylic acid
CAS 893723-49-4C8H5N3O2
7-Bromo-2-methylpyrido[2,3-b]pyrazine chemical structure, C8H6BrN3, CAS 155629-94-0
7-Bromo-2-methylpyrido[2,3-b]pyrazine
CAS 155629-94-0C8H6BrN3
6-Methylpyrido[2,3-b]pyrazine chemical structure, C8H7N3, CAS 155629-96-2
6-Methylpyrido[2,3-b]pyrazine
CAS 155629-96-2C8H7N3
Pyrido[2,3-b]pyrazin-8-amine chemical structure, C7H6N4, CAS 224193-81-1
Pyrido[2,3-b]pyrazin-8-amine
CAS 224193-81-1C7H6N4
Ethyl pyrido[2,3-b]pyrazine-2-carboxylate chemical structure, C10H9N3O2, CAS 475112-15-3
Ethyl pyrido[2,3-b]pyrazine-2-carboxylate
CAS 475112-15-3C10H9N3O2
Pyrido[2,3-b]pyrazine-6-carbaldehyde chemical structure, C8H5N3O, CAS 874279-16-0
Pyrido[2,3-b]pyrazine-6-carbaldehyde
CAS 874279-16-0C8H5N3O
2,3-Dichloropyrido[2,3-b]pyrazine chemical structure, C7H3Cl2N3, CAS 25710-18-3
2,3-Dichloropyrido[2,3-b]pyrazine
CAS 25710-18-3C7H3Cl2N3
2,3-Dibromopyrido[2,3-b]pyrazine chemical structure, C7H3Br2N3, CAS 114391-58-1
2,3-Dibromopyrido[2,3-b]pyrazine
CAS 114391-58-1C7H3Br2N3