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Murcko scaffold

Ring system with 3 rings and 23 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
19
With full pages
7
Scaffold SMILES

O=C(Oc1ccc(C(=S)N2CCOCC2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Oc1ccc(C(=S)N2CCOCC2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

4-(Morpholin-4-ylcarbonothioyl)phenyl 4-fluorobenzoate chemical structure, C18H16FNO3S, CAS 443676-84-4
4-(Morpholin-4-ylcarbonothioyl)phenyl 4-fluorobenzoate
CAS 443676-84-4C18H16FNO3S
4-(Morpholin-4-ylcarbonothioyl)phenyl 2-fluorobenzoate chemical structure, C18H16FNO3S, CAS 443733-11-7
4-(Morpholin-4-ylcarbonothioyl)phenyl 2-fluorobenzoate
CAS 443733-11-7C18H16FNO3S
4-(4-Morpholinylcarbothioyl)phenyl 3-chlorobenzoate chemical structure, C18H16ClNO3S, CAS 432000-47-0
4-(4-Morpholinylcarbothioyl)phenyl 3-chlorobenzoate
CAS 432000-47-0C18H16ClNO3S
2-Bromo-4-(morpholin-4-ylcarbonothioyl)phenyl 2-fluorobenzoate chemical structure, C18H15BrFNO3S, CAS 443895-36-1
2-Bromo-4-(morpholin-4-ylcarbonothioyl)phenyl 2-fluorobenzoate
CAS 443895-36-1C18H15BrFNO3S
2-Chloro-4-(4-morpholinylcarbothioyl)phenyl 2-fluorobenzoate chemical structure, C18H15ClFNO3S, CAS 444081-28-1
2-Chloro-4-(4-morpholinylcarbothioyl)phenyl 2-fluorobenzoate
CAS 444081-28-1C18H15ClFNO3S
[4-(Morpholine-4-carbothioyl)phenyl] 2,4-dichlorobenzoate chemical structure, C18H15Cl2NO3S, CAS 311331-08-5
[4-(Morpholine-4-carbothioyl)phenyl] 2,4-dichlorobenzoate
CAS 311331-08-5C18H15Cl2NO3S
[2-Methoxy-4-(morpholine-4-carbothioyl)phenyl] 4-nitrobenzoate chemical structure, C19H18N2O6S, CAS 327032-58-6
[2-Methoxy-4-(morpholine-4-carbothioyl)phenyl] 4-nitrobenzoate
CAS 327032-58-6C19H18N2O6S
3,4,5-Trimethoxy-benzoic acid 4-(morpholine-4-carbothioyl)-phenyl ester chemical structure, C21H23NO6S, CAS 309953-70-6
3,4,5-Trimethoxy-benzoic acid 4-(morpholine-4-carbothioyl)-phenyl ester
CAS 309953-70-6C21H23NO6S
3-Methyl-benzoic acid 2-methoxy-4-(morpholine-4-carbothioyl)-phenyl ester chemical structure, C20H21NO4S, CAS 331835-68-8
3-Methyl-benzoic acid 2-methoxy-4-(morpholine-4-carbothioyl)-phenyl ester
CAS 331835-68-8C20H21NO4S
2-Ethoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 3-nitrobenzoate chemical structure, C20H20N2O6S, CAS 331835-73-5
2-Ethoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 3-nitrobenzoate
CAS 331835-73-5C20H20N2O6S
2-Methoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 4-chloro-2-nitrobenzoate chemical structure, C19H17ClN2O6S, CAS 443672-15-9
2-Methoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 4-chloro-2-nitrobenzoate
CAS 443672-15-9C19H17ClN2O6S
2,6-Dimethoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 4-chloro-3-nitrobenzoate chemical structure, C20H19ClN2O7S, CAS 443678-02-2
2,6-Dimethoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 4-chloro-3-nitrobenzoate
CAS 443678-02-2C20H19ClN2O7S
2-Chloro-6-methoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 4-nitrobenzoate chemical structure, C19H17ClN2O6S, CAS 443648-01-9
2-Chloro-6-methoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 4-nitrobenzoate
CAS 443648-01-9C19H17ClN2O6S
2,6-Dimethoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 4-fluorobenzoate chemical structure, C20H20FNO5S, CAS 443896-76-2
2,6-Dimethoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 4-fluorobenzoate
CAS 443896-76-2C20H20FNO5S
2-Bromo-4-(morpholin-4-ylcarbonothioyl)phenyl 3,4-dimethoxybenzoate chemical structure, C20H20BrNO5S, CAS 443673-16-3
2-Bromo-4-(morpholin-4-ylcarbonothioyl)phenyl 3,4-dimethoxybenzoate
CAS 443673-16-3C20H20BrNO5S
2-Chloro-4-(morpholin-4-ylcarbonothioyl)phenyl 2-bromobenzoate chemical structure, C18H15BrClNO3S, CAS 443644-81-3
2-Chloro-4-(morpholin-4-ylcarbonothioyl)phenyl 2-bromobenzoate
CAS 443644-81-3C18H15BrClNO3S
2-Methoxy-4-(4-morpholinylcarbonothioyl)phenyl 2-nitrobenzoate chemical structure, C19H18N2O6S, CAS 5878-54-6
2-Methoxy-4-(4-morpholinylcarbonothioyl)phenyl 2-nitrobenzoate
CAS 5878-54-6C19H18N2O6S
2-Bromo-6-ethoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 4-nitrobenzoate chemical structure, C20H19BrN2O6S, CAS 6066-31-5
2-Bromo-6-ethoxy-4-(morpholin-4-ylcarbonothioyl)phenyl 4-nitrobenzoate
CAS 6066-31-5C20H19BrN2O6S
2-Chloro-4-(morpholin-4-ylcarbonothioyl)phenyl 4-chloro-2-nitrobenzoate chemical structure, C18H14Cl2N2O5S, CAS 443673-84-5
2-Chloro-4-(morpholin-4-ylcarbonothioyl)phenyl 4-chloro-2-nitrobenzoate
CAS 443673-84-5C18H14Cl2N2O5S