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Murcko scaffold

5(6H)-Quinolinone, 7,8-dihydro- scaffold

90 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
90
With full pages
21
Scaffold SMILES

O=C1CCCc2ncccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5(6H)-Quinolinone, 7,8-dihydro- page
Murcko scaffold O=C1CCCc2ncccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 90 chemicals

4-Methyl-7,8-dihydroquinolin-5(6H)-one chemical structure, C10H11NO, CAS 53654-28-7
4-Methyl-7,8-dihydroquinolin-5(6H)-one
CAS 53654-28-7C10H11NO
2-Chloro-5,6,7,8-tetrahydroquinolin-5-one chemical structure, C9H8ClNO, CAS 124467-36-3
2-Chloro-5,6,7,8-tetrahydroquinolin-5-one
CAS 124467-36-3C9H8ClNO
3-Methyl-7,8-dihydroquinolin-5(6H)-one chemical structure, C10H11NO, CAS 60247-70-3
3-Methyl-7,8-dihydroquinolin-5(6H)-one
CAS 60247-70-3C10H11NO
3-Methyl-7,8-dihydroquinolin-5(6H)-one hydrochloride chemical structure, C10H12ClNO, CAS 78257-02-0
3-Methyl-7,8-dihydroquinolin-5(6H)-one hydrochloride
CAS 78257-02-0C10H12ClNO
2-((3-Cyano-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinolin-2-yl)thio)acetamide chemical structure, C14H15N3O2S, CAS 363620-82-0
2-((3-Cyano-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinolin-2-yl)thio)acetamide
CAS 363620-82-0C14H15N3O2S
7,7-Dimethyl-5-oxo-2-prop-2-enylsulfanyl-6,8-dihydroquinoline-3-carbonitrile chemical structure, C15H16N2OS, CAS 488814-02-4
7,7-Dimethyl-5-oxo-2-prop-2-enylsulfanyl-6,8-dihydroquinoline-3-carbonitrile
CAS 488814-02-4C15H16N2OS
2-((3-Cyano-5-oxo-5,6,7,8-tetrahydroquinolin-2-yl)thio)acetamide chemical structure, C12H11N3O2S, CAS 442557-81-5
2-((3-Cyano-5-oxo-5,6,7,8-tetrahydroquinolin-2-yl)thio)acetamide
CAS 442557-81-5C12H11N3O2S
5(6H)-Quinolinone, 7,8-dihydro- chemical structure, C9H9NO, CAS 53400-41-2
5(6H)-Quinolinone, 7,8-dihydro-
CAS 53400-41-2C9H9NO
2-(Methylthio)-5-oxo-5,6,7,8-tetrahydroquinoline-3-carbonitrile chemical structure, C11H10N2OS, CAS 370843-66-6
2-(Methylthio)-5-oxo-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS 370843-66-6C11H10N2OS
2-Methoxy-7,8-dihydroquinolin-5(6H)-one chemical structure, C10H11NO2, CAS 57311-38-3
2-Methoxy-7,8-dihydroquinolin-5(6H)-one
CAS 57311-38-3C10H11NO2
2-Methyl-7,8-dihydro-6H-quinolin-5-one chemical structure, C10H11NO, CAS 27463-92-9
2-Methyl-7,8-dihydro-6H-quinolin-5-one
CAS 27463-92-9C10H11NO
7,7-Dimethyl-2-(trifluoromethyl)-7,8-dihydroquinolin-5(6H)-one chemical structure, C12H12F3NO, CAS 205582-86-1
7,7-Dimethyl-2-(trifluoromethyl)-7,8-dihydroquinolin-5(6H)-one
CAS 205582-86-1C12H12F3NO
3-Nitro-7,8-dihydroquinolin-5(6H)-one chemical structure, C9H8N2O3, CAS 87883-18-9
3-Nitro-7,8-dihydroquinolin-5(6H)-one
CAS 87883-18-9C9H8N2O3
3-Chloro-7,8-dihydroquinolin-5(6H)-one chemical structure, C9H8ClNO, CAS 127724-75-8
3-Chloro-7,8-dihydroquinolin-5(6H)-one
CAS 127724-75-8C9H8ClNO
2-Trifluoromethyl-7,8-dihydro-6H-quinolin-5-one chemical structure, C10H8F3NO, CAS 890301-86-7
2-Trifluoromethyl-7,8-dihydro-6H-quinolin-5-one
CAS 890301-86-7C10H8F3NO
7,8-Dihydro-3,7,7-trimethyl-5(6H)-quinolinone hydrochloride chemical structure, C12H16ClNO, CAS 60247-73-6
7,8-Dihydro-3,7,7-trimethyl-5(6H)-quinolinone hydrochloride
CAS 60247-73-6C12H16ClNO
5(6H)-Quinolinone, 7,8-dihydro-7,7-dimethyl- chemical structure, C11H13NO, CAS 5220-63-3
5(6H)-Quinolinone, 7,8-dihydro-7,7-dimethyl-
CAS 5220-63-3C11H13NO
2,4-Dimethyl-5,6,7,8-tetrahydroquinolin-5-one chemical structure, C11H13NO, CAS 34192-19-3
2,4-Dimethyl-5,6,7,8-tetrahydroquinolin-5-one
CAS 34192-19-3C11H13NO
7-Quinolinecarboxamide, 5,6,7,8-tetrahydro-5-oxo- chemical structure, C10H10N2O2, CAS 54318-91-1
7-Quinolinecarboxamide, 5,6,7,8-tetrahydro-5-oxo-
CAS 54318-91-1C10H10N2O2
8,8-Dimethyl-5,6,7,8-tetrahydroquinolin-5-one chemical structure, C11H13NO, CAS 343770-84-3
8,8-Dimethyl-5,6,7,8-tetrahydroquinolin-5-one
CAS 343770-84-3C11H13NO
Ethyl 5-Oxo-5,6,7,8-tetrahydroquinoline-3-carboxylate chemical structure, C12H13NO3, CAS 106960-78-5
Ethyl 5-Oxo-5,6,7,8-tetrahydroquinoline-3-carboxylate
CAS 106960-78-5C12H13NO3
Ethyl 7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carboxylate chemical structure, C14H17NO3, CAS 106944-52-9
Ethyl 7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carboxylate
CAS 106944-52-9C14H17NO3
3-Hydroxy-7-methyl-5,6,7,8-tetrahydroquinolin-5-one chemical structure, C10H11NO2, CAS 123094-71-3
3-Hydroxy-7-methyl-5,6,7,8-tetrahydroquinolin-5-one
CAS 123094-71-3C10H11NO2
7-Methyl-3-nitro-5,6,7,8-tetrahydroquinolin-5-one chemical structure, C10H10N2O3, CAS 123094-67-7
7-Methyl-3-nitro-5,6,7,8-tetrahydroquinolin-5-one
CAS 123094-67-7C10H10N2O3