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Murcko scaffold

4-(1,3-Oxazol-2-yl)piperidine scaffold

64 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
64
With full pages
8
Scaffold SMILES

c1coc(C2CCNCC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(1,3-Oxazol-2-yl)piperidine page
Murcko scaffold c1coc(C2CCNCC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 64 chemicals

2-Piperidin-4-yl-oxazole-4-carboxylic acid ethyl ester chemical structure, C11H16N2O3, CAS 672310-05-3
2-Piperidin-4-yl-oxazole-4-carboxylic acid ethyl ester
CAS 672310-05-3C11H16N2O3
4-(1,3-Oxazol-2-yl)piperidine chemical structure, C8H12N2O, CAS 340700-99-4
4-(1,3-Oxazol-2-yl)piperidine
CAS 340700-99-4C8H12N2O
tert-Butyl 4-(4-(chloromethyl)oxazol-2-yl)piperidine-1-carboxylate chemical structure, C14H21ClN2O3, CAS 1037797-57-1
tert-Butyl 4-(4-(chloromethyl)oxazol-2-yl)piperidine-1-carboxylate
CAS 1037797-57-1C14H21ClN2O3
Ethyl 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)oxazole-4-carboxylate chemical structure, C16H24N2O5, CAS 1037797-93-5
Ethyl 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)oxazole-4-carboxylate
CAS 1037797-93-5C16H24N2O5
tert-Butyl 4-(4-(hydroxymethyl)oxazol-2-yl)piperidine-1-carboxylate chemical structure, C14H22N2O4, CAS 1044136-33-5
tert-Butyl 4-(4-(hydroxymethyl)oxazol-2-yl)piperidine-1-carboxylate
CAS 1044136-33-5C14H22N2O4
2-(1-(Methylsulfonyl)piperidin-4-yl)oxazole-4-carboxylic acid chemical structure, C10H14N2O5S, CAS 1297541-98-0
2-(1-(Methylsulfonyl)piperidin-4-yl)oxazole-4-carboxylic acid
CAS 1297541-98-0C10H14N2O5S
Ethyl 2-(1-(methylsulfonyl)piperidin-4-yl)oxazole-4-carboxylate chemical structure, C12H18N2O5S, CAS 1297541-94-6
Ethyl 2-(1-(methylsulfonyl)piperidin-4-yl)oxazole-4-carboxylate
CAS 1297541-94-6C12H18N2O5S
Methyl 2-(1-boc-piperidin-4-yl)oxazole-4-carboxylate chemical structure, C15H22N2O5, CAS 922516-07-2
Methyl 2-(1-boc-piperidin-4-yl)oxazole-4-carboxylate
CAS 922516-07-2C15H22N2O5
2-{1-[(tert-Butoxy)carbonyl]piperidin-4-yl}-1,3-oxazole-4-carboxylic acid chemical structure, C14H20N2O5, CAS 922516-08-3
2-{1-[(tert-Butoxy)carbonyl]piperidin-4-yl}-1,3-oxazole-4-carboxylic acid
CAS 922516-08-3C14H20N2O5
4-Hydroxy-4-oxazol-2-yl-piperidine-1-carboxylic acid tert-butyl ester chemical structure, C13H20N2O4, CAS 955027-72-2
4-Hydroxy-4-oxazol-2-yl-piperidine-1-carboxylic acid tert-butyl ester
CAS 955027-72-2C13H20N2O4
4-(4,5-Dimethyl-oxazol-2-yl)-piperidine chemical structure, C10H16N2O, CAS 1368927-77-8
4-(4,5-Dimethyl-oxazol-2-yl)-piperidine
CAS 1368927-77-8C10H16N2O
4-(5-Methyl-1,3-oxazol-2-yl)piperidine chemical structure, C9H14N2O, CAS 1216285-03-8
4-(5-Methyl-1,3-oxazol-2-yl)piperidine
CAS 1216285-03-8C9H14N2O
Ethyl 5-methyl-2-(piperidin-4-yl)-1,3-oxazole-4-carboxylate chemical structure, C12H18N2O3, CAS 1520871-32-2
Ethyl 5-methyl-2-(piperidin-4-yl)-1,3-oxazole-4-carboxylate
CAS 1520871-32-2C12H18N2O3
5-Methyl-2-(piperidin-4-yl)-1,3-oxazole-4-carboxylic acid chemical structure, C10H14N2O3, CAS 1522926-83-5
5-Methyl-2-(piperidin-4-yl)-1,3-oxazole-4-carboxylic acid
CAS 1522926-83-5C10H14N2O3
2-(Piperidin-4-yl)-1,3-oxazole-4-carboxylic acid chemical structure, C9H12N2O3, CAS 1519539-52-6
2-(Piperidin-4-yl)-1,3-oxazole-4-carboxylic acid
CAS 1519539-52-6C9H12N2O3
5-(tert-Butyl)-2-(piperidin-4-yl)oxazole chemical structure, C12H20N2O, CAS 1216074-97-3
5-(tert-Butyl)-2-(piperidin-4-yl)oxazole
CAS 1216074-97-3C12H20N2O
2-(Piperidin-4-yl)-1,3-oxazole-5-carboxylic acid chemical structure, C9H12N2O3, CAS 1557402-03-5
2-(Piperidin-4-yl)-1,3-oxazole-5-carboxylic acid
CAS 1557402-03-5C9H12N2O3
Methyl 2-(piperidin-4-yl)-1,3-oxazole-5-carboxylate chemical structure, C10H14N2O3, CAS 1554426-14-0
Methyl 2-(piperidin-4-yl)-1,3-oxazole-5-carboxylate
CAS 1554426-14-0C10H14N2O3
5-Oxazolecarboxylic acid, 2-(4-piperidinyl)-, ethyl ester chemical structure, C11H16N2O3, CAS 1555987-78-4
5-Oxazolecarboxylic acid, 2-(4-piperidinyl)-, ethyl ester
CAS 1555987-78-4C11H16N2O3
2-(Piperidin-4-yl)-4-(trifluoromethyl)oxazole chemical structure, C9H11F3N2O, CAS 1779992-78-7
2-(Piperidin-4-yl)-4-(trifluoromethyl)oxazole
CAS 1779992-78-7C9H11F3N2O
Methyl 2-(piperidin-4-yl)-1,3-oxazole-4-carboxylate chemical structure, C10H14N2O3, CAS 927800-98-4
Methyl 2-(piperidin-4-yl)-1,3-oxazole-4-carboxylate
CAS 927800-98-4C10H14N2O3
2-{1-[(tert-Butoxy)carbonyl]piperidin-4-yl}-1,3-oxazole-5-carboxylic acid chemical structure, C14H20N2O5, CAS 1909319-03-4
2-{1-[(tert-Butoxy)carbonyl]piperidin-4-yl}-1,3-oxazole-5-carboxylic acid
CAS 1909319-03-4C14H20N2O5
4-(1,3-Oxazol-2-yl)piperidine dihydrochloride chemical structure, C8H14Cl2N2O, CAS 1909305-79-8
4-(1,3-Oxazol-2-yl)piperidine dihydrochloride
CAS 1909305-79-8C8H14Cl2N2O
4-(5-Methyl-1,3-oxazol-2-yl)piperidine hydrochloride chemical structure, C9H15ClN2O, CAS 1955548-15-8
4-(5-Methyl-1,3-oxazol-2-yl)piperidine hydrochloride
CAS 1955548-15-8C9H15ClN2O