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Murcko scaffold

Ring system with 2 rings and 13 atoms

125 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
125
With full pages
7
Scaffold SMILES

O=c1[nH]cc(C2CCCO2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cc(C2CCCO2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 125 of 125 chemicals

5-[(2R,4S,5R)-4-Hydroxy-5-(methoxymethoxymethyl)oxolan-2-yl]-1,3-dimethylpyrimidine-2,4-dione chemical structure, C13H20N2O6, CAS 103003-56-1
5-[(2R,4S,5R)-4-Hydroxy-5-(methoxymethoxymethyl)oxolan-2-yl]-1,3-dimethylpyrimidine-2,4-dione
CAS 103003-56-1C13H20N2O6
5-[2-Deoxy-5-O-(methoxymethyl)-|A-D-threo-pentofuranosyl]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione chemical structure, C13H20N2O6, CAS 103003-57-2
5-[2-Deoxy-5-O-(methoxymethyl)-|A-D-threo-pentofuranosyl]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione
CAS 103003-57-2C13H20N2O6
5-(3-Deoxy-|A-D-erythro-pentofuranosyl)-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione chemical structure, C11H16N2O5, CAS 78064-58-1
5-(3-Deoxy-|A-D-erythro-pentofuranosyl)-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione
CAS 78064-58-1C11H16N2O5
Uracil,5-alpha-D-ribofuranosyl-,2',3',5'-triacetate chemical structure, C15H18N2O9, CAS 28455-49-4
Uracil,5-alpha-D-ribofuranosyl-,2',3',5'-triacetate
CAS 28455-49-4C15H18N2O9
5-[5-O-(1-Oxohexadecyl)-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C25H42N2O7, CAS 132471-84-2
5-[5-O-(1-Oxohexadecyl)-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione
CAS 132471-84-2C25H42N2O7
1,2,3,6-Tetrahydro-2,6-dioxo-5-|A-D-ribofuranosyl-4-pyrimidinecarboxylicacid chemical structure, C10H12N2O8, CAS 1987879-60-6
1,2,3,6-Tetrahydro-2,6-dioxo-5-|A-D-ribofuranosyl-4-pyrimidinecarboxylicacid
CAS 1987879-60-6C10H12N2O8
5-(5-O-Acetyl-|A-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione chemical structure, C11H14N2O7, CAS 83931-90-2
5-(5-O-Acetyl-|A-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione
CAS 83931-90-2C11H14N2O7
1,2,3,6-Tetrahydro-2,6-dioxo-5-|A-D-ribofuranosyl-4-pyrimidinecarboxaldehyde chemical structure, C10H12N2O7, CAS 1987879-61-7
1,2,3,6-Tetrahydro-2,6-dioxo-5-|A-D-ribofuranosyl-4-pyrimidinecarboxaldehyde
CAS 1987879-61-7C10H12N2O7
6-(Hydroxymethyl)-5-|A-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione chemical structure, C10H14N2O7, CAS 1987879-59-3
6-(Hydroxymethyl)-5-|A-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione
CAS 1987879-59-3C10H14N2O7
6-Methoxy-5-|A-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione chemical structure, C10H14N2O7, CAS 1987879-62-8
6-Methoxy-5-|A-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione
CAS 1987879-62-8C10H14N2O7
2,4(1H,3H)-Pyrimidinedione,5-[2-C-(hydroxymethyl)-|A-ribofuranosyl]- chemical structure, C10H14N2O7, CAS 76742-62-6
2,4(1H,3H)-Pyrimidinedione,5-[2-C-(hydroxymethyl)-|A-ribofuranosyl]-
CAS 76742-62-6C10H14N2O7
2,4(1H,3H)-Pyrimidinedione,5-(6-deoxy-|A-allofuranosyl)- chemical structure, C10H14N2O6, CAS 70280-09-0
2,4(1H,3H)-Pyrimidinedione,5-(6-deoxy-|A-allofuranosyl)-
CAS 70280-09-0C10H14N2O6
5-[5-O-(Hydroxymercaptophosphinyl)-|A-Dribofuranosyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C9H12N2O8PS+, CAS 714231-75-1
5-[5-O-(Hydroxymercaptophosphinyl)-|A-Dribofuranosyl]-2,4(1H,3H)-pyrimidinedione
CAS 714231-75-1C9H12N2O8PS+
Uracil, 5-(2 inverted exclamation marka-O-methyl-|A-D-ribofuranosyl)- chemical structure, C10H14N2O6, CAS 3121-87-7
Uracil, 5-(2 inverted exclamation marka-O-methyl-|A-D-ribofuranosyl)-
CAS 3121-87-7C10H14N2O6
5-(3-O-Methyl-|A-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione chemical structure, C10H14N2O6, CAS 51293-40-4
5-(3-O-Methyl-|A-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione
CAS 51293-40-4C10H14N2O6
1(2H)-Pyrimidinepropanamide,3,4-dihydro-2,4-dioxo-5-|A-D-ribofuranosyl-N-[2-[(trifluoroacetyl)amino]ethyl]- chemical structure, C16H21F3N4O8, CAS 694438-39-6
1(2H)-Pyrimidinepropanamide,3,4-dihydro-2,4-dioxo-5-|A-D-ribofuranosyl-N-[2-[(trifluoroacetyl)amino]ethyl]-
CAS 694438-39-6C16H21F3N4O8
6-Chloro-1-methyl-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C28H55ClN2O6Si3, CAS 1613530-19-0
6-Chloro-1-methyl-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione
CAS 1613530-19-0C28H55ClN2O6Si3
1-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-6-methyl-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C35H72N2O7Si4, CAS 1613530-09-8
1-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-6-methyl-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione
CAS 1613530-09-8C35H72N2O7Si4
1,6-Dimethyl-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C29H58N2O6Si3, CAS 1613530-12-3
1,6-Dimethyl-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione
CAS 1613530-12-3C29H58N2O6Si3
1-(2-Propen-1-yl)-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C30H58N2O6Si3, CAS 1613530-14-5
1-(2-Propen-1-yl)-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione
CAS 1613530-14-5C30H58N2O6Si3
1-(2-Propyn-1-yl)-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C30H56N2O6Si3, CAS 1613530-16-7
1-(2-Propyn-1-yl)-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione
CAS 1613530-16-7C30H56N2O6Si3
1-Methyl-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C28H56N2O6Si3, CAS 1613530-11-2
1-Methyl-5-[2,3,5-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-|A-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione
CAS 1613530-11-2C28H56N2O6Si3
Ethyl3,4-dihydro-2,4-dioxo-5-|A-D-ribofuranosyl-1(2H)-pyrimidinepropanoate chemical structure, C14H20N2O8, CAS 694438-38-5
Ethyl3,4-dihydro-2,4-dioxo-5-|A-D-ribofuranosyl-1(2H)-pyrimidinepropanoate
CAS 694438-38-5C14H20N2O8
1,3-Dimethyl-5-(2-O-methyl-|A-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione chemical structure, C12H18N2O6, CAS 133648-44-9
1,3-Dimethyl-5-(2-O-methyl-|A-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione
CAS 133648-44-9C12H18N2O6