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Murcko scaffold

Ring system with 3 rings and 21 atoms

8 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 21
Chemicals: 8
With full pages: 1

Scaffold SMILES

O=C(NCCn1ccc(-c2ccccc2)n1)c1ccn[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(NCCn1ccc(-c2ccccc2)n1)c1ccn[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

(S)-5-Acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide chemical structure, C19H17ClN6O2, CAS 1297537-33-7

(S)-5-Acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide

CAS 1297537-33-7C₁₉H₁₇ClN₆O₂

Darolutamide chemical structure, C19H19ClN6O2, CAS 1297538-32-9

CAS 1297538-32-9C₁₉H₁₉ClN₆O₂

(S)-5-(1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-ylcarbamoyl)-1H-pyrazole-3-carboxylic acid chemical structure, C18H15ClN6O3, CAS 1297538-47-6

(S)-5-(1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-ylcarbamoyl)-1H-pyrazole-3-carboxylic acid

CAS 1297538-47-6C₁₈H₁₅ClN₆O₃

N-[(2S)-1-[3-(3-Chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-5-[(1R)-1-hydroxyethyl]-1H-pyrazole-3-carboxamide chemical structure, C19H19ClN6O2, CAS 1976022-49-7

N-[(2S)-1-[3-(3-Chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-5-[(1R)-1-hydroxyethyl]-1H-pyrazole-3-carboxamide

CAS 1976022-49-7C₁₉H₁₉ClN₆O₂

N-[(2S)-1-[3-(3-Chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-5-[(1S)-1-hydroxyethyl]-1H-pyrazole-3-carboxamide chemical structure, C19H19ClN6O2, CAS 1976022-48-6

N-[(2S)-1-[3-(3-Chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-5-[(1S)-1-hydroxyethyl]-1H-pyrazole-3-carboxamide

CAS 1976022-48-6C₁₉H₁₉ClN₆O₂

Darolutamide, (R)- chemical structure, C19H19ClN6O2, CAS 2407645-49-0

Darolutamide, (R)-

CAS 2407645-49-0C₁₉H₁₉ClN₆O₂

Darolutamide-d4 chemical structure, C19H19ClN6O2, CAS 2484757-20-0

Darolutamide-d4

CAS 2484757-20-0C₁₉H₁₉ClN₆O₂

Darolutamide D4 chemical structure, C19H19ClN6O2, CAS 2484757-19-7

Darolutamide D4

CAS 2484757-19-7C₁₉H₁₉ClN₆O₂