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Murcko scaffold

2-(1,2,4-Oxadiazol-3-yl)pyridine scaffold

82 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
82
With full pages
6
Scaffold SMILES

c1ccc(-c2ncon2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1,2,4-Oxadiazol-3-yl)pyridine page
Murcko scaffold c1ccc(-c2ncon2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 82 chemicals

2-(1,2,4-Oxadiazol-3-yl)pyridine chemical structure, C7H5N3O, CAS 13389-59-8
2-(1,2,4-Oxadiazol-3-yl)pyridine
CAS 13389-59-8C7H5N3O
5-Methyl-3-(pyridin-2-yl)-1,2,4-oxadiazole chemical structure, C8H7N3O, CAS 10350-68-2
5-Methyl-3-(pyridin-2-yl)-1,2,4-oxadiazole
CAS 10350-68-2C8H7N3O
5-Propan-2-yl-3-pyridin-2-yl-1,2,4-oxadiazole chemical structure, C10H11N3O, CAS 443328-44-7
5-Propan-2-yl-3-pyridin-2-yl-1,2,4-oxadiazole
CAS 443328-44-7C10H11N3O
3-Chloro-5-(trifluoromethyl)-2-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C9H2ClF6N3O, CAS 303997-65-1
3-Chloro-5-(trifluoromethyl)-2-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 303997-65-1C9H2ClF6N3O
4-(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)butanoic acid chemical structure, C11H11N3O3, CAS 439108-12-0
4-(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)butanoic acid
CAS 439108-12-0C11H11N3O3
3-(3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanoic acid chemical structure, C10H9N3O3, CAS 99185-87-2
3-(3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-yl)propanoic acid
CAS 99185-87-2C10H9N3O3
2-[5-(Trichloromethyl)-1,2,4-oxadiazol-3-yl]pyridine chemical structure, C8H4Cl3N3O, CAS 1208-06-6
2-[5-(Trichloromethyl)-1,2,4-oxadiazol-3-yl]pyridine
CAS 1208-06-6C8H4Cl3N3O
2-[3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2,4-oxadiazol-5-yl]guanidine chemical structure, C9H6ClF3N6O, CAS 338407-16-2
2-[3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2,4-oxadiazol-5-yl]guanidine
CAS 338407-16-2C9H6ClF3N6O
3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-amine chemical structure, C7H6N4O, CAS 114065-40-6
3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-amine
CAS 114065-40-6C7H6N4O
2-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)pyridine chemical structure, C8H6ClN3O, CAS 90002-06-5
2-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)pyridine
CAS 90002-06-5C8H6ClN3O
3-(3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-yl)propan-1-amine chemical structure, C10H12N4O, CAS 926198-60-9
3-(3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-yl)propan-1-amine
CAS 926198-60-9C10H12N4O
2-[3-(2-Pyridinyl)-1,2,4-oxadiazol-5-yl]-acetic acid chemical structure, C9H7N3O3, CAS 761390-89-0
2-[3-(2-Pyridinyl)-1,2,4-oxadiazol-5-yl]-acetic acid
CAS 761390-89-0C9H7N3O3
[3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-yl]methanamine chemical structure, C8H8N4O, CAS 936939-88-7
[3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-yl]methanamine
CAS 936939-88-7C8H8N4O
1-(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)ethanamine chemical structure, C9H10N4O, CAS 936940-60-2
1-(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)ethanamine
CAS 936940-60-2C9H10N4O
2-[3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-yl]ethan-1-amine chemical structure, C9H10N4O, CAS 936940-28-2
2-[3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-yl]ethan-1-amine
CAS 936940-28-2C9H10N4O
3-(5-Bromopyridin-2-yl)-1,2,4-oxadiazole chemical structure, C7H4BrN3O, CAS 380380-68-7
3-(5-Bromopyridin-2-yl)-1,2,4-oxadiazole
CAS 380380-68-7C7H4BrN3O
3-(5-Bromopyridin-2-yl)-5-methyl-1,2,4-oxadiazole chemical structure, C8H6BrN3O, CAS 380380-61-0
3-(5-Bromopyridin-2-yl)-5-methyl-1,2,4-oxadiazole
CAS 380380-61-0C8H6BrN3O
(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)methanol chemical structure, C8H7N3O2, CAS 187970-01-0
(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)methanol
CAS 187970-01-0C8H7N3O2
N-Methyl-1-(3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl)methanamine chemical structure, C9H10N4O, CAS 1041571-45-2
N-Methyl-1-(3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl)methanamine
CAS 1041571-45-2C9H10N4O
Ethyl 3-(pyridin-2-yl)-1,2,4-oxadiazole-5-carboxylate chemical structure, C10H9N3O3, CAS 163719-76-4
Ethyl 3-(pyridin-2-yl)-1,2,4-oxadiazole-5-carboxylate
CAS 163719-76-4C10H9N3O3
3-(Methylsulfanyl)-1-[3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl]propan-1-amine chemical structure, C11H14N4OS, CAS 1042511-23-8
3-(Methylsulfanyl)-1-[3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl]propan-1-amine
CAS 1042511-23-8C11H14N4OS
3-(Methylsulfonyl)-1-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)propan-1-amine chemical structure, C11H14N4O3S, CAS 1036438-62-6
3-(Methylsulfonyl)-1-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)propan-1-amine
CAS 1036438-62-6C11H14N4O3S
I+/--Methyl-3-(2-pyridinyl)-1,2,4-oxadiazole-5-ethanamine chemical structure, C10H12N4O, CAS 1098387-30-4
I+/--Methyl-3-(2-pyridinyl)-1,2,4-oxadiazole-5-ethanamine
CAS 1098387-30-4C10H12N4O
1-{3-[5-(Trifluoromethyl)pyridin-2-yl]-1,2,4-oxadiazol-5-yl}methanamine trifluoroacetate chemical structure, C11H8F6N4O3, CAS 1208081-75-7
1-{3-[5-(Trifluoromethyl)pyridin-2-yl]-1,2,4-oxadiazol-5-yl}methanamine trifluoroacetate
CAS 1208081-75-7C11H8F6N4O3