Murcko scaffold
N-(Thiophen-3-yl)benzamide scaffold
70 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 70
- With full pages
- 28
Scaffold SMILES
O=C(Nc1ccsc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 70 chemicals
N-(Thiophen-3-yl)benzamide
CAS 79128-75-9C11H9NOS
![Methyl 3-[(2-fluorobenzoyl)amino]-2-thiophenecarboxylate chemical structure, C13H10FNO3S, CAS 544700-17-6](/s/HDUAAFYMMMHQCX-UHFFFAOYSA-N.svg)
Methyl 3-[(2-fluorobenzoyl)amino]-2-thiophenecarboxylate
CAS 544700-17-6C13H10FNO3S
![Methyl3-[(2,4-dichlorobenzoyl)amino]thiophene-2-carboxylate chemical structure, C13H9Cl2NO3S, CAS 424812-72-6](/s/TZTNJHQHNQQEPB-UHFFFAOYSA-N.svg)
Methyl3-[(2,4-dichlorobenzoyl)amino]thiophene-2-carboxylate
CAS 424812-72-6C13H9Cl2NO3S
Methyl 3-(benzoylamino)-2-thiophenecarboxylate
CAS 79128-70-4C13H11NO3S
![Methyl 3-[(2-ethoxybenzoyl)amino]-2-thiophenecarboxylate chemical structure, C15H15NO4S, CAS 329049-95-8](/s/MJMKZIZKIDMUSO-UHFFFAOYSA-N.svg)
Methyl 3-[(2-ethoxybenzoyl)amino]-2-thiophenecarboxylate
CAS 329049-95-8C15H15NO4S
Methyl 3-(4-nitrobenzamido)thiophene-2-carboxylate
CAS 183495-96-7C13H10N2O5S
![3-[[(4-Methoxyphenyl)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester chemical structure, C14H13NO4S, CAS 544656-81-7](/s/IQHFVFGUPWQQCP-UHFFFAOYSA-N.svg)
3-[[(4-Methoxyphenyl)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester
CAS 544656-81-7C14H13NO4S
Methyl 3-({2-chloro-5-nitrobenzoyl}amino)-2-thiophenecarboxylate
CAS 372094-29-6C13H9ClN2O5S
![Methyl 3-[(4-bromobenzoyl)amino]thiophene-2-carboxylate chemical structure, C13H10BrNO3S, CAS 355384-02-0](/s/JBVPNQJOEIEWBB-UHFFFAOYSA-N.svg)
Methyl 3-[(4-bromobenzoyl)amino]thiophene-2-carboxylate
CAS 355384-02-0C13H10BrNO3S
![Methyl 3-[(3-methoxybenzoyl)amino]thiophene-2-carboxylate chemical structure, C14H13NO4S, CAS 371948-16-2](/s/QLWDSUPKFMVWAH-UHFFFAOYSA-N.svg)
Methyl 3-[(3-methoxybenzoyl)amino]thiophene-2-carboxylate
CAS 371948-16-2C14H13NO4S
![Methyl 3-[[4-(2-methylpropoxy)benzoyl]amino]thiophene-2-carboxylate chemical structure, C17H19NO4S, CAS 350988-73-7](/s/MXAHZTIIXRJGDF-UHFFFAOYSA-N.svg)
Methyl 3-[[4-(2-methylpropoxy)benzoyl]amino]thiophene-2-carboxylate
CAS 350988-73-7C17H19NO4S
![Methyl 3-[(3,4-dichlorobenzoyl)amino]-2-thiophenecarboxylate chemical structure, C13H9Cl2NO3S, CAS 541526-98-1](/s/CDTZBYYMQZLWLC-UHFFFAOYSA-N.svg)
Methyl 3-[(3,4-dichlorobenzoyl)amino]-2-thiophenecarboxylate
CAS 541526-98-1C13H9Cl2NO3S
![Methyl 3-[(2,5-dichlorobenzoyl)amino]thiophene-2-carboxylate chemical structure, C13H9Cl2NO3S, CAS 557780-19-5](/s/DGYZSMNZJNRMNA-UHFFFAOYSA-N.svg)
Methyl 3-[(2,5-dichlorobenzoyl)amino]thiophene-2-carboxylate
CAS 557780-19-5C13H9Cl2NO3S
![Methyl 3-[(5-chloro-2-methoxybenzoyl)amino]-2-thiophenecarboxylate chemical structure, C14H12ClNO4S, CAS 541534-91-2](/s/HKCSUYBSPHDUQJ-UHFFFAOYSA-N.svg)
Methyl 3-[(5-chloro-2-methoxybenzoyl)amino]-2-thiophenecarboxylate
CAS 541534-91-2C14H12ClNO4S
![Methyl 3-[(2,4-dimethoxybenzoyl)amino]-2-thiophenecarboxylate chemical structure, C15H15NO5S, CAS 362499-93-2](/s/VGZCSROFTUEUEU-UHFFFAOYSA-N.svg)
Methyl 3-[(2,4-dimethoxybenzoyl)amino]-2-thiophenecarboxylate
CAS 362499-93-2C15H15NO5S
Methyl 3-(3-nitrobenzamido)thiophene-2-carboxylate
CAS 352700-30-2C13H10N2O5S
![Ethyl 4-[(4-chlorobenzoyl)amino]-2-methyl-3-thiophenecarboxylate chemical structure, C15H14ClNO3S, CAS 371782-32-0](/s/DQZXTHZAQYESSN-UHFFFAOYSA-N.svg)
Ethyl 4-[(4-chlorobenzoyl)amino]-2-methyl-3-thiophenecarboxylate
CAS 371782-32-0C15H14ClNO3S
Methyl 3-((4-methylbenzoyl)amino)-2-thiophenecarboxylate
CAS 478080-01-2C14H13NO3S
![3-[(4-Methylbenzoyl)amino]-2-thiophene-carboxylic acid chemical structure, C13H11NO3S, CAS 478080-03-4](/s/OEGYJETWWYWHAS-UHFFFAOYSA-N.svg)
3-[(4-Methylbenzoyl)amino]-2-thiophene-carboxylic acid
CAS 478080-03-4C13H11NO3S
3-(2-Chlorobenzamido)thiophene-2-carboxylic acid
CAS 439111-81-6C12H8ClNO3S
![Methyl 3-amino-5-[(2-methoxy-2-oxoethyl)sulfanyl]-4-(4-methylbenzamido)thiophene-2-carboxylate chemical structure, C17H18N2O5S2, CAS 851626-96-5](/s/ZVIYIZMVEDOHNI-UHFFFAOYSA-N.svg)
Methyl 3-amino-5-[(2-methoxy-2-oxoethyl)sulfanyl]-4-(4-methylbenzamido)thiophene-2-carboxylate
CAS 851626-96-5C17H18N2O5S2
![Methyl 3-[(3-chlorobenzoyl)amino]-2-thiophenecarboxylate chemical structure, C13H10ClNO3S, CAS 420091-37-8](/s/GXZIILPZIOBKIY-UHFFFAOYSA-N.svg)
Methyl 3-[(3-chlorobenzoyl)amino]-2-thiophenecarboxylate
CAS 420091-37-8C13H10ClNO3S
3-(Benzoylamino)-2-thiophenecarboxylic acid
CAS 147123-66-8C12H9NO3S
![Methyl 3-([3-(chloromethyl)benzoyl]amino)thiophene-2-carboxylate chemical structure, C14H12ClNO3S, CAS 306935-11-5](/s/PTDJCZIESZVKBW-UHFFFAOYSA-N.svg)
Methyl 3-([3-(chloromethyl)benzoyl]amino)thiophene-2-carboxylate
CAS 306935-11-5C14H12ClNO3S
- 3-[(4-Chlorobenzoyl)amino]-2-thiophenecarboxylic acid675828-66-7C12H8ClNO3S
- Methyl 3-(2-chlorobenzamido)thiophene-2-carboxylate478080-02-3C13H10ClNO3S
- Methyl 3-[(4-chlorobenzoyl)amino]-4-methyl-2-thiophenecarboxylate676318-51-7C14H12ClNO3S
- Methyl 3-{[4-(tert-butyl)benzoyl]amino}-4-methyl-2-thiophenecarboxylate676318-52-8C18H21NO3S
- Methyl 3-[(4-cyanobenzoyl)amino]thiophene-2-carboxylate330942-99-9C14H10N2O3S
- N-(2-Acetylthiophen-3-yl)phthalamic acid175602-10-5C14H11NO4S
- Methyl 3-[(4-fluorobenzoyl)amino]-2-thiophenecarboxylate478080-00-1C13H10FNO3S
- Methyl 3-[(4-fluorobenzoyl)amino]-4-methyl-2-thiophenecarboxylate677706-82-0C14H12FNO3S
- Methyl 3-{[(4-ethoxyphenyl)carbonyl]amino}thiophene-2-carboxylate420093-07-8C15H15NO4S
- Methyl 3-[(3,4-dimethoxybenzoyl)amino]-2-thiophenecarboxylate438475-20-8C15H15NO5S
- Methyl 3-[(2,3,4,5,6-pentafluorobenzoyl)amino]-2-thiophenecarboxylate545365-96-6C13H6F5NO3S
- Methyl 3-[(2,4-dichlorobenzoyl)amino]-4-methyl-2-thiophenecarboxylate866150-13-2C14H11Cl2NO3S
- 3-{[4-(tert-Butyl)benzoyl]amino}-4-methyl-2-thiophenecarboxylic acid866150-50-7C17H19NO3S
- 3-[(2,4-Dichlorobenzoyl)amino]-4-methyl-2-thiophenecarboxylic acid866151-45-3C13H9Cl2NO3S
- 3-[(4-Methoxybenzoyl)amino]-4-methyl-2-thiophenecarboxylic acid866152-21-8C14H13NO4S
- 3-{[3-(Trifluoromethyl)benzoyl]amino}-2-thiophenecarboxylic acid866150-49-4C13H8F3NO3S
- Methyl 3-{[3-(trifluoromethyl)benzoyl]amino}-2-thiophenecarboxylate866150-53-0C14H10F3NO3S
- 3-[(4-Fluorobenzoyl)amino]-4-methyl-2-thiophenecarboxylic acid866152-22-9C13H10FNO3S
- 3-[(2,6-Dichlorobenzoyl)amino]-4-methyl-2-thiophenecarboxylic acid866152-24-1C13H9Cl2NO3S
- 3-[(2,4-Dichlorobenzoyl)amino]-2-thiophenecarboxylic acid926221-62-7C12H7Cl2NO3S
- Methyl 3-[(2-fluorobenzoyl)amino]-4-methyl-2-thiophenecarboxylate866150-47-2C14H12FNO3S
- 4-Methyl-3-[(3-nitrobenzoyl)amino]-2-thiophenecarboxylic acid866152-23-0C13H10N2O5S
- 3-[(2,6-Dichlorobenzoyl)amino]-2-thiophenecarboxylic acid866152-20-7C12H7Cl2NO3S
- Methyl 3-[(4-chlorobenzoyl)amino]-2-thiophenecarboxylate544421-24-1C13H10ClNO3S
Related scaffolds
Same ring framework with different atoms or bond orders
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O=C(N=c1[nH]ncs1)c1ccccc187 chemicals
c1ccc(OCc2ccco2)cc175 chemicals
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c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
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O=C(Nc1cccs1)c1ccccc152 chemicals
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c1ccc(CSc2nncs2)cc144 chemicals