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Murcko scaffold

Ring system with 2 rings and 18 atoms

108 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
108
With full pages
12
Scaffold SMILES

O=C(CNc1ccccc1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNc1ccccc1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 108 chemicals

2-(3-Methoxy-N-methylsulfonylanilino)-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C18H22N2O5S, CAS 366835-07-6
2-(3-Methoxy-N-methylsulfonylanilino)-N-[(4-methoxyphenyl)methyl]acetamide
CAS 366835-07-6C18H22N2O5S
2-(2-Methoxy-5-methyl-N-methylsulfonylanilino)-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C19H24N2O5S, CAS 428501-66-0
2-(2-Methoxy-5-methyl-N-methylsulfonylanilino)-N-[(4-methoxyphenyl)methyl]acetamide
CAS 428501-66-0C19H24N2O5S
N-[(4-Chlorophenyl)methyl]-2-(4-fluoro-N-methylsulfonylanilino)acetamide chemical structure, C16H16ClFN2O3S, CAS 428486-27-5
N-[(4-Chlorophenyl)methyl]-2-(4-fluoro-N-methylsulfonylanilino)acetamide
CAS 428486-27-5C16H16ClFN2O3S
2-(3-Chloro-4-methoxy-N-methylsulfonylanilino)-N-[(4-chlorophenyl)methyl]acetamide chemical structure, C17H18Cl2N2O4S, CAS 592468-14-9
2-(3-Chloro-4-methoxy-N-methylsulfonylanilino)-N-[(4-chlorophenyl)methyl]acetamide
CAS 592468-14-9C17H18Cl2N2O4S
2-(3-Chloro-4-methoxy-N-methylsulfonylanilino)-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C18H21ClN2O5S, CAS 428496-73-5
2-(3-Chloro-4-methoxy-N-methylsulfonylanilino)-N-[(4-methoxyphenyl)methyl]acetamide
CAS 428496-73-5C18H21ClN2O5S
N-(2-Chlorobenzyl)-2-[2,4-dimethoxy(methylsulfonyl)anilino]acetamide chemical structure, C18H21ClN2O5S, CAS 667874-62-6
N-(2-Chlorobenzyl)-2-[2,4-dimethoxy(methylsulfonyl)anilino]acetamide
CAS 667874-62-6C18H21ClN2O5S
N-[(4-Chlorophenyl)methyl]-2-(3-fluoro-N-methylsulfonylanilino)acetamide chemical structure, C16H16ClFN2O3S, CAS 694487-01-9
N-[(4-Chlorophenyl)methyl]-2-(3-fluoro-N-methylsulfonylanilino)acetamide
CAS 694487-01-9C16H16ClFN2O3S
N-Benzyl-2-(5-chloro-2-methyl-N-methylsulfonylanilino)-N-methylacetamide chemical structure, C18H21ClN2O3S, CAS 333320-23-3
N-Benzyl-2-(5-chloro-2-methyl-N-methylsulfonylanilino)-N-methylacetamide
CAS 333320-23-3C18H21ClN2O3S
N-Benzyl-2-[2,4-dimethoxy(methylsulfonyl)anilino]acetamide chemical structure, C18H22N2O5S, CAS 491844-74-7
N-Benzyl-2-[2,4-dimethoxy(methylsulfonyl)anilino]acetamide
CAS 491844-74-7C18H22N2O5S
N-[(4-Chlorophenyl)methyl]-2-(2-ethoxy-N-methylsulfonylanilino)acetamide chemical structure, C18H21ClN2O4S, CAS 335211-80-8
N-[(4-Chlorophenyl)methyl]-2-(2-ethoxy-N-methylsulfonylanilino)acetamide
CAS 335211-80-8C18H21ClN2O4S
N-Benzyl-2-[(3,4-dimethyl-phenyl)-methanesulfonyl-amino]-N-methyl-acetamide chemical structure, C19H24N2O3S, CAS 333446-36-9
N-Benzyl-2-[(3,4-dimethyl-phenyl)-methanesulfonyl-amino]-N-methyl-acetamide
CAS 333446-36-9C19H24N2O3S
N-Benzyl-2-(3-chloro-4-methyl-N-methylsulfonylanilino)acetamide chemical structure, C17H19ClN2O3S, CAS 425607-60-9
N-Benzyl-2-(3-chloro-4-methyl-N-methylsulfonylanilino)acetamide
CAS 425607-60-9C17H19ClN2O3S
2-(4-Ethoxy-N-methylsulfonylanilino)-N-[(2-methylphenyl)methyl]acetamide chemical structure, C19H24N2O4S, CAS 357323-04-7
2-(4-Ethoxy-N-methylsulfonylanilino)-N-[(2-methylphenyl)methyl]acetamide
CAS 357323-04-7C19H24N2O4S
2-(4-Chloro-2-methyl-N-methylsulfonylanilino)-N-[(4-methylphenyl)methyl]acetamide chemical structure, C18H21ClN2O3S, CAS 425679-34-1
2-(4-Chloro-2-methyl-N-methylsulfonylanilino)-N-[(4-methylphenyl)methyl]acetamide
CAS 425679-34-1C18H21ClN2O3S
N-(2,4-Dichlorobenzyl)-N~2~-(4-ethoxyphenyl)-N~2~-(methylsulfonyl)glycinamide chemical structure, C18H20Cl2N2O4S, CAS 444058-36-0
N-(2,4-Dichlorobenzyl)-N~2~-(4-ethoxyphenyl)-N~2~-(methylsulfonyl)glycinamide
CAS 444058-36-0C18H20Cl2N2O4S
N-(2-Methoxybenzyl)-N~2~-(2-methylphenyl)-N~2~-(methylsulfonyl)glycinamide chemical structure, C18H22N2O4S, CAS 335394-08-6
N-(2-Methoxybenzyl)-N~2~-(2-methylphenyl)-N~2~-(methylsulfonyl)glycinamide
CAS 335394-08-6C18H22N2O4S
2-[5-Chloro-2-methoxy(methylsulfonyl)anilino]-N-(2-methylbenzyl)acetamide chemical structure, C18H21ClN2O4S, CAS 425666-77-9
2-[5-Chloro-2-methoxy(methylsulfonyl)anilino]-N-(2-methylbenzyl)acetamide
CAS 425666-77-9C18H21ClN2O4S
N-[(2,4-Dichlorophenyl)methyl]-2-(2-methoxy-N-methylsulfonylanilino)acetamide chemical structure, C17H18Cl2N2O4S, CAS 664348-45-2
N-[(2,4-Dichlorophenyl)methyl]-2-(2-methoxy-N-methylsulfonylanilino)acetamide
CAS 664348-45-2C17H18Cl2N2O4S
N-Benzyl-2-(3-fluoro-N-methylsulfonylanilino)-N-methylacetamide chemical structure, C17H19FN2O3S, CAS 664316-98-7
N-Benzyl-2-(3-fluoro-N-methylsulfonylanilino)-N-methylacetamide
CAS 664316-98-7C17H19FN2O3S
N-[(4-Chlorophenyl)methyl]-2-(3-methoxy-N-methylsulfonylanilino)acetamide chemical structure, C17H19ClN2O4S, CAS 428464-38-4
N-[(4-Chlorophenyl)methyl]-2-(3-methoxy-N-methylsulfonylanilino)acetamide
CAS 428464-38-4C17H19ClN2O4S
2-(3-Acetyl-N-methylsulfonylanilino)-N-[(2-chlorophenyl)methyl]acetamide chemical structure, C18H19ClN2O4S, CAS 831237-00-4
2-(3-Acetyl-N-methylsulfonylanilino)-N-[(2-chlorophenyl)methyl]acetamide
CAS 831237-00-4C18H19ClN2O4S
N-[(2-Methoxyphenyl)methyl]-2-[N-methylsulfonyl-3-(trifluoromethyl)anilino]acetamide chemical structure, C18H19F3N2O4S, CAS 367912-57-0
N-[(2-Methoxyphenyl)methyl]-2-[N-methylsulfonyl-3-(trifluoromethyl)anilino]acetamide
CAS 367912-57-0C18H19F3N2O4S
N-[(2,4-Dichlorophenyl)methyl]-2-(4-ethyl-N-methylsulfonylanilino)acetamide chemical structure, C18H20Cl2N2O3S, CAS 532423-39-5
N-[(2,4-Dichlorophenyl)methyl]-2-(4-ethyl-N-methylsulfonylanilino)acetamide
CAS 532423-39-5C18H20Cl2N2O3S
2-(2,5-Dichloro-N-methylsulfonylanilino)-N-[(2-methoxyphenyl)methyl]acetamide chemical structure, C17H18Cl2N2O4S, CAS 446869-24-5
2-(2,5-Dichloro-N-methylsulfonylanilino)-N-[(2-methoxyphenyl)methyl]acetamide
CAS 446869-24-5C17H18Cl2N2O4S