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Murcko scaffold

1,8-Naphthyridin-2(1H)-one scaffold

229 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
229
With full pages
21
Scaffold SMILES

O=c1ccc2cccnc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,8-Naphthyridin-2(1H)-one page
Murcko scaffold O=c1ccc2cccnc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 229 chemicals

7-(Dimethylamino)-4-methoxy-1-methyl-1,8-naphthyridin-2(1H)-one chemical structure, C12H15N3O2, CAS 57980-10-6
7-(Dimethylamino)-4-methoxy-1-methyl-1,8-naphthyridin-2(1H)-one
CAS 57980-10-6C12H15N3O2
1,8-Naphthyridin-2(1H)-one chemical structure, C8H6N2O, CAS 15936-09-1
1,8-Naphthyridin-2(1H)-one
CAS 15936-09-1C8H6N2O
7-[Bis(2-hydroxyethyl)amino]-1-methyl-1,8-naphthyridin-2-one chemical structure, C13H17N3O3, CAS 91860-14-9
7-[Bis(2-hydroxyethyl)amino]-1-methyl-1,8-naphthyridin-2-one
CAS 91860-14-9C13H17N3O3
4-Hydrazino[1,8]naphthyridin-2-ol chemical structure, C8H8N4O, CAS 59514-94-2
4-Hydrazino[1,8]naphthyridin-2-ol
CAS 59514-94-2C8H8N4O
4-Methyl-1,8-naphthyridin-2-ol chemical structure, C9H8N2O, CAS 889940-20-9
4-Methyl-1,8-naphthyridin-2-ol
CAS 889940-20-9C9H8N2O
1,8-Naphthyridin-2(1H)-one, 3-methyl-1-(3-methylbutyl)- chemical structure, C14H18N2O, CAS 146967-52-4
1,8-Naphthyridin-2(1H)-one, 3-methyl-1-(3-methylbutyl)-
CAS 146967-52-4C14H18N2O
7-Amino-4-methyl-1,8-naphthyridin-2-ol chemical structure, C9H9N3O, CAS 1569-15-9
7-Amino-4-methyl-1,8-naphthyridin-2-ol
CAS 1569-15-9C9H9N3O
7-Methyl-1,8-naphthyridin-2-ol chemical structure, C9H8N2O, CAS 1569-11-5
7-Methyl-1,8-naphthyridin-2-ol
CAS 1569-11-5C9H8N2O
5,7-Dimethyl-1,8-naphthyridin-2(1H)-one chemical structure, C10H10N2O, CAS 51420-71-4
5,7-Dimethyl-1,8-naphthyridin-2(1H)-one
CAS 51420-71-4C10H10N2O
1,8-Naphthyridine-2,4-dicarboxaldehyde, 7,8-dihydro-7-oxo- chemical structure, C10H6N2O3, CAS 89804-71-7
1,8-Naphthyridine-2,4-dicarboxaldehyde, 7,8-dihydro-7-oxo-
CAS 89804-71-7C10H6N2O3
7-Amino-2-oxo-1,2-dihydro-1,8-naphthyridine-4-carboxylic acid chemical structure, C9H7N3O3, CAS 90323-16-3
7-Amino-2-oxo-1,2-dihydro-1,8-naphthyridine-4-carboxylic acid
CAS 90323-16-3C9H7N3O3
7-Amino-1,8-naphthyridin-2(1H)-one chemical structure, C8H7N3O, CAS 1931-44-8
7-Amino-1,8-naphthyridin-2(1H)-one
CAS 1931-44-8C8H7N3O
7-Amino-3-methyl[1,8]naphthyridin-2-ol chemical structure, C9H9N3O, CAS 1931-46-0
7-Amino-3-methyl[1,8]naphthyridin-2-ol
CAS 1931-46-0C9H9N3O
(7-Amino-2-hydroxy[1,8]naphthyridin-4-yl)acetic acid chemical structure, C10H9N3O3, CAS 1931-45-9
(7-Amino-2-hydroxy[1,8]naphthyridin-4-yl)acetic acid
CAS 1931-45-9C10H9N3O3
5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2(1H)-one chemical structure, C10H4F6N2O, CAS 51420-73-6
5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2(1H)-one
CAS 51420-73-6C10H4F6N2O
5-Chloro-1,8-naphthyridin-2(1H)-one chemical structure, C8H5ClN2O, CAS 250264-28-9
5-Chloro-1,8-naphthyridin-2(1H)-one
CAS 250264-28-9C8H5ClN2O
5,7-Dichloro-1,8-naphthyridin-2(1H)-one chemical structure, C8H4Cl2N2O, CAS 210642-96-9
5,7-Dichloro-1,8-naphthyridin-2(1H)-one
CAS 210642-96-9C8H4Cl2N2O
2-(2-Oxo-1H-1,8-naphthyridin-3-yl)acetic acid chemical structure, C10H8N2O3, CAS 216679-01-5
2-(2-Oxo-1H-1,8-naphthyridin-3-yl)acetic acid
CAS 216679-01-5C10H8N2O3
Ethyl 7-amino-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate chemical structure, C11H11N3O3, CAS 17517-68-9
Ethyl 7-amino-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate
CAS 17517-68-9C11H11N3O3
1-Butyl-4-chloro-1,8-naphthyridin-2(1H)-one chemical structure, C12H13ClN2O, CAS 583031-56-5
1-Butyl-4-chloro-1,8-naphthyridin-2(1H)-one
CAS 583031-56-5C12H13ClN2O
2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carbohydrazide chemical structure, C9H8N4O2, CAS 60467-92-7
2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carbohydrazide
CAS 60467-92-7C9H8N4O2
2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carbonitrile chemical structure, C9H5N3O, CAS 60467-72-3
2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carbonitrile
CAS 60467-72-3C9H5N3O
Ethyl 2-hydroxy-1,8-naphthyridine-3-carboxylate chemical structure, C11H10N2O3, CAS 5174-90-3
Ethyl 2-hydroxy-1,8-naphthyridine-3-carboxylate
CAS 5174-90-3C11H10N2O3
7-Amino-1-methyl-1,8-naphthyridin-2(1H)-one chemical structure, C9H9N3O, CAS 49655-99-4
7-Amino-1-methyl-1,8-naphthyridin-2(1H)-one
CAS 49655-99-4C9H9N3O