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Murcko scaffold

Isothiazole scaffold

1,868 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
1,868
With full pages
279
Scaffold SMILES

c1cnsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Isothiazole page
Murcko scaffold c1cnsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,729 to 1,776 of 1,868 chemicals

(3R)-3-Amino-3-(1,2-thiazol-5-yl)propanamide chemical structure, C6H9N3OS, CAS 1998646-85-7
(3R)-3-Amino-3-(1,2-thiazol-5-yl)propanamide
CAS 1998646-85-7C6H9N3OS
(3S)-3-Amino-3-(3-methoxy-1,2-thiazol-5-yl)propanamide chemical structure, C7H11N3O2S, CAS 1997428-01-9
(3S)-3-Amino-3-(3-methoxy-1,2-thiazol-5-yl)propanamide
CAS 1997428-01-9C7H11N3O2S
(Butan-2-yl)[(4-chloro-3-methoxy-1,2-thiazol-5-yl)methyl]amine chemical structure, C9H15ClN2OS, CAS 2137567-28-1
(Butan-2-yl)[(4-chloro-3-methoxy-1,2-thiazol-5-yl)methyl]amine
CAS 2137567-28-1C9H15ClN2OS
tert-Butyl[(4-chloro-3-methoxy-1,2-thiazol-5-yl)methyl]amine chemical structure, C9H15ClN2OS, CAS 2137704-68-6
tert-Butyl[(4-chloro-3-methoxy-1,2-thiazol-5-yl)methyl]amine
CAS 2137704-68-6C9H15ClN2OS
[(4-Chloro-3-methoxy-1,2-thiazol-5-yl)methyl](pentan-3-yl)amine chemical structure, C10H17ClN2OS, CAS 2138195-73-8
[(4-Chloro-3-methoxy-1,2-thiazol-5-yl)methyl](pentan-3-yl)amine
CAS 2138195-73-8C10H17ClN2OS
2-Amino-3-(1,2-thiazol-5-yl)propanamide chemical structure, C6H9N3OS, CAS 2004135-75-3
2-Amino-3-(1,2-thiazol-5-yl)propanamide
CAS 2004135-75-3C6H9N3OS
3-Amino-1-(3-methoxy-1,2-thiazol-4-yl)-2-methylpropan-1-ol chemical structure, C8H14N2O2S, CAS 2138406-75-2
3-Amino-1-(3-methoxy-1,2-thiazol-4-yl)-2-methylpropan-1-ol
CAS 2138406-75-2C8H14N2O2S
Methyl 2-[(5-formyl-1,2-thiazol-3-yl)oxy]acetate chemical structure, C7H7NO4S, CAS 2138419-47-1
Methyl 2-[(5-formyl-1,2-thiazol-3-yl)oxy]acetate
CAS 2138419-47-1C7H7NO4S
2,2-Difluoro-2-(1,2-thiazol-4-yl)acetic acid chemical structure, C5H3F2NO2S, CAS 2026256-57-3
2,2-Difluoro-2-(1,2-thiazol-4-yl)acetic acid
CAS 2026256-57-3C5H3F2NO2S
4-Bromo-5-(3-chloro-2-methylpropyl)-1,2-thiazole chemical structure, C7H9BrClNS, CAS 2137791-24-1
4-Bromo-5-(3-chloro-2-methylpropyl)-1,2-thiazole
CAS 2137791-24-1C7H9BrClNS
4-Bromo-5-(3-bromo-2-methylpropyl)-1,2-thiazole chemical structure, C7H9Br2NS, CAS 2137702-26-0
4-Bromo-5-(3-bromo-2-methylpropyl)-1,2-thiazole
CAS 2137702-26-0C7H9Br2NS
tert-Butyl N-[2-(4-bromo-1,2-thiazol-5-yl)-2-oxoethyl]-N-methylcarbamate chemical structure, C11H15BrN2O3S, CAS 2138433-27-7
tert-Butyl N-[2-(4-bromo-1,2-thiazol-5-yl)-2-oxoethyl]-N-methylcarbamate
CAS 2138433-27-7C11H15BrN2O3S
tert-Butyl N-[(2R)-1-(4-bromo-1,2-thiazol-5-yl)-1-oxopropan-2-yl]carbamate chemical structure, C11H15BrN2O3S, CAS 2137144-55-7
tert-Butyl N-[(2R)-1-(4-bromo-1,2-thiazol-5-yl)-1-oxopropan-2-yl]carbamate
CAS 2137144-55-7C11H15BrN2O3S
tert-Butyl N-methyl-N-[1-oxo-1-(1,2-thiazol-4-yl)propan-2-yl]carbamate chemical structure, C12H18N2O3S, CAS 2018942-43-1
tert-Butyl N-methyl-N-[1-oxo-1-(1,2-thiazol-4-yl)propan-2-yl]carbamate
CAS 2018942-43-1C12H18N2O3S
tert-Butyl N-ethyl-N-[2-oxo-2-(1,2-thiazol-4-yl)ethyl]carbamate chemical structure, C12H18N2O3S, CAS 2022913-19-3
tert-Butyl N-ethyl-N-[2-oxo-2-(1,2-thiazol-4-yl)ethyl]carbamate
CAS 2022913-19-3C12H18N2O3S
(2S)-2-(Methylamino)-1-(1,2-thiazol-3-yl)propan-1-one chemical structure, C7H10N2OS, CAS 2107807-20-3
(2S)-2-(Methylamino)-1-(1,2-thiazol-3-yl)propan-1-one
CAS 2107807-20-3C7H10N2OS
tert-Butyl N-[1-oxo-1-(1,2-thiazol-5-yl)propan-2-yl]carbamate chemical structure, C11H16N2O3S, CAS 2028414-39-1
tert-Butyl N-[1-oxo-1-(1,2-thiazol-5-yl)propan-2-yl]carbamate
CAS 2028414-39-1C11H16N2O3S
5-(3-Chloro-2-methylpropyl)-3-methoxy-1,2-thiazole chemical structure, C8H12ClNOS, CAS 1995669-07-2
5-(3-Chloro-2-methylpropyl)-3-methoxy-1,2-thiazole
CAS 1995669-07-2C8H12ClNOS
5-[2-(Chloromethyl)-2-methylbutyl]-1,2-thiazole chemical structure, C9H14ClNS, CAS 2002786-76-5
5-[2-(Chloromethyl)-2-methylbutyl]-1,2-thiazole
CAS 2002786-76-5C9H14ClNS
2-Amino-1-(1,2-thiazol-4-yl)propan-1-one chemical structure, C6H8N2OS, CAS 1514758-12-3
2-Amino-1-(1,2-thiazol-4-yl)propan-1-one
CAS 1514758-12-3C6H8N2OS
3-(Methylamino)-1-(1,2-thiazol-4-yl)propan-1-one chemical structure, C7H10N2OS, CAS 2023992-61-0
3-(Methylamino)-1-(1,2-thiazol-4-yl)propan-1-one
CAS 2023992-61-0C7H10N2OS
tert-Butyl N-ethyl-N-[2-oxo-2-(1,2-thiazol-5-yl)ethyl]carbamate chemical structure, C12H18N2O3S, CAS 2016301-35-0
tert-Butyl N-ethyl-N-[2-oxo-2-(1,2-thiazol-5-yl)ethyl]carbamate
CAS 2016301-35-0C12H18N2O3S
4-Amino-1-(1,2-thiazol-5-yl)butan-2-one chemical structure, C7H10N2OS, CAS 2012067-83-1
4-Amino-1-(1,2-thiazol-5-yl)butan-2-one
CAS 2012067-83-1C7H10N2OS
1-(Methylamino)-3-(1,2-thiazol-5-yl)propan-2-one chemical structure, C7H10N2OS, CAS 1998296-50-6
1-(Methylamino)-3-(1,2-thiazol-5-yl)propan-2-one
CAS 1998296-50-6C7H10N2OS