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Murcko scaffold

Ring system with 3 rings and 20 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
19
With full pages
5
Scaffold SMILES

O=C(Nc1ncc2c(n1)CCCC2=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ncc2c(n1)CCCC2=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-3,5-dimethoxybenzamide chemical structure, C19H21N3O4, CAS 775292-96-1
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-3,5-dimethoxybenzamide
CAS 775292-96-1C19H21N3O4
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-3-methoxybenzamide chemical structure, C18H19N3O3, CAS 774563-57-4
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-3-methoxybenzamide
CAS 774563-57-4C18H19N3O3
3,5-Dimethoxy-N-(7-methyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide chemical structure, C18H19N3O4, CAS 877793-41-4
3,5-Dimethoxy-N-(7-methyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide
CAS 877793-41-4C18H19N3O4
3-Methoxy-N-(7-methyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide chemical structure, C17H17N3O3, CAS 777872-48-7
3-Methoxy-N-(7-methyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide
CAS 777872-48-7C17H17N3O3
N-(7,7-Dimethyl-5-oxo-6,8-dihydroquinazolin-2-yl)benzamide chemical structure, C17H17N3O2, CAS 375836-77-4
N-(7,7-Dimethyl-5-oxo-6,8-dihydroquinazolin-2-yl)benzamide
CAS 375836-77-4C17H17N3O2
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-4-nitrobenzamide chemical structure, C17H16N4O4, CAS 327981-35-1
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-4-nitrobenzamide
CAS 327981-35-1C17H16N4O4
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-3-methylbenzamide chemical structure, C18H19N3O2, CAS 774563-55-2
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-3-methylbenzamide
CAS 774563-55-2C18H19N3O2
2-Chloro-N-(7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide chemical structure, C17H16ClN3O2, CAS 774563-58-5
2-Chloro-N-(7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide
CAS 774563-58-5C17H16ClN3O2
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-4-methoxybenzamide chemical structure, C18H19N3O3, CAS 774563-52-9
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-4-methoxybenzamide
CAS 774563-52-9C18H19N3O3
4-Chloro-N-(7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide chemical structure, C17H16ClN3O2, CAS 774563-51-8
4-Chloro-N-(7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide
CAS 774563-51-8C17H16ClN3O2
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-2-methoxybenzamide chemical structure, C18H19N3O3, CAS 774563-59-6
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-2-methoxybenzamide
CAS 774563-59-6C18H19N3O3
3-Chloro-N-(7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide chemical structure, C17H16ClN3O2, CAS 774563-56-3
3-Chloro-N-(7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide
CAS 774563-56-3C17H16ClN3O2
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-4-methylbenzamide chemical structure, C18H19N3O2, CAS 774563-50-7
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-4-methylbenzamide
CAS 774563-50-7C18H19N3O2
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-4-fluorobenzamide chemical structure, C17H16FN3O2, CAS 413616-40-7
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-4-fluorobenzamide
CAS 413616-40-7C17H16FN3O2
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-3,4,5-trimethoxybenzamide chemical structure, C20H23N3O5, CAS 523990-60-5
N-(7,7-Dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)-3,4,5-trimethoxybenzamide
CAS 523990-60-5C20H23N3O5
2,4-Dichloro-N-(7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide chemical structure, C17H15Cl2N3O2, CAS 774563-60-9
2,4-Dichloro-N-(7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide
CAS 774563-60-9C17H15Cl2N3O2
4-Methoxy-N-(7-methyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide chemical structure, C17H17N3O3, CAS 775293-66-8
4-Methoxy-N-(7-methyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide
CAS 775293-66-8C17H17N3O3
N-(7,7-Dimethyl-5-oxo-6,8-dihydroquinazolin-2-yl)-3-fluorobenzamide chemical structure, C17H16FN3O2, CAS 327981-55-5
N-(7,7-Dimethyl-5-oxo-6,8-dihydroquinazolin-2-yl)-3-fluorobenzamide
CAS 327981-55-5C17H16FN3O2
N-(4,7,7-Trimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide chemical structure, C18H19N3O2, CAS 941238-65-9
N-(4,7,7-Trimethyl-5-oxo-5,6,7,8-tetrahydroquinazolin-2-yl)benzamide
CAS 941238-65-9C18H19N3O2