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Murcko scaffold

Ring system with 3 rings and 20 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
20
With full pages
3
Scaffold SMILES

O=C1OCCN1c1ccc(OCc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OCCN1c1ccc(OCc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

Cimoxatone chemical structure, C19H18N2O4, CAS 73815-11-9
Cimoxatone
CAS 73815-11-9C19H18N2O4
MD 770222 chemical structure, C18H16N2O4, CAS 70133-35-6
MD 770222
CAS 70133-35-6C18H16N2O4
2-Oxazolidinone, 3-(4-((3-chlorophenyl)methoxy)phenyl)-5-((methylamino)methyl)-, monomethanesulfonate chemical structure, C19H23ClN2O6S, CAS 84269-97-6
2-Oxazolidinone, 3-(4-((3-chlorophenyl)methoxy)phenyl)-5-((methylamino)methyl)-, monomethanesulfonate
CAS 84269-97-6C19H23ClN2O6S
3-(4-((3-Chlorophenyl)methoxy)phenyl)-5-((methylamino)methyl)-2-oxazolidinone chemical structure, C18H19ClN2O3, CAS 73423-36-6
3-(4-((3-Chlorophenyl)methoxy)phenyl)-5-((methylamino)methyl)-2-oxazolidinone
CAS 73423-36-6C18H19ClN2O3
Almoxatone chemical structure, C18H19ClN2O3, CAS 84145-89-1
Almoxatone
CAS 84145-89-1C18H19ClN2O3
2-Oxazolidinone, 5-(hydroxymethyl)-3-(4-((3-(trifluoromethyl)phenyl)methoxy)phenyl)- chemical structure, C18H16F3NO4, CAS 64590-26-7
2-Oxazolidinone, 5-(hydroxymethyl)-3-(4-((3-(trifluoromethyl)phenyl)methoxy)phenyl)-
CAS 64590-26-7C18H16F3NO4
2-Oxazolidinone, 3-(4-((3-chlorophenyl)methoxy)phenyl)-5-(hydroxymethyl)- chemical structure, C17H16ClNO4, CAS 64590-28-9
2-Oxazolidinone, 3-(4-((3-chlorophenyl)methoxy)phenyl)-5-(hydroxymethyl)-
CAS 64590-28-9C17H16ClNO4
2-Oxazolidinone, 3-(4-((4-fluorophenyl)methoxy)phenyl)-5-(hydroxymethyl)- chemical structure, C17H16FNO4, CAS 64590-36-9
2-Oxazolidinone, 3-(4-((4-fluorophenyl)methoxy)phenyl)-5-(hydroxymethyl)-
CAS 64590-36-9C17H16FNO4
2-Oxazolidinone, 3-(4-((3-fluorophenyl)methoxy)phenyl)-5-(hydroxymethyl)- chemical structure, C17H16FNO4, CAS 64590-38-1
2-Oxazolidinone, 3-(4-((3-fluorophenyl)methoxy)phenyl)-5-(hydroxymethyl)-
CAS 64590-38-1C17H16FNO4
2-Oxazolidinone, 3-(4-((3-bromophenyl)methoxy)phenyl)-5-(hydroxymethyl)- chemical structure, C17H16BrNO4, CAS 70133-32-3
2-Oxazolidinone, 3-(4-((3-bromophenyl)methoxy)phenyl)-5-(hydroxymethyl)-
CAS 70133-32-3C17H16BrNO4
2-Oxazolidinone, 3-(4-((3-chlorophenyl)methoxy)phenyl)-5-((propylamino)methyl)-, monohydrochloride, hydrate chemical structure, C20H24Cl2N2O3, CAS 84460-00-4
2-Oxazolidinone, 3-(4-((3-chlorophenyl)methoxy)phenyl)-5-((propylamino)methyl)-, monohydrochloride, hydrate
CAS 84460-00-4C20H24Cl2N2O3
2-Oxazolidinone, 3-(4-((3-chlorophenyl)methoxy)phenyl)-5-((2-propynylamino)methyl)-, monohydrochloride chemical structure, C20H20Cl2N2O3, CAS 84460-03-7
2-Oxazolidinone, 3-(4-((3-chlorophenyl)methoxy)phenyl)-5-((2-propynylamino)methyl)-, monohydrochloride
CAS 84460-03-7C20H20Cl2N2O3
3-(4-((3-Chlorobenzyl)oxy)phenyl)-2-oxooxazolidine-5-carboxylic acid chemical structure, C17H14ClNO5, CAS 87186-61-6
3-(4-((3-Chlorobenzyl)oxy)phenyl)-2-oxooxazolidine-5-carboxylic acid
CAS 87186-61-6C17H14ClNO5
3-[4-(Benzyloxy)phenyl]-5-(ethoxymethyl)-1,3-oxazolidin-2-one chemical structure, C19H21NO4, CAS 73422-04-5
3-[4-(Benzyloxy)phenyl]-5-(ethoxymethyl)-1,3-oxazolidin-2-one
CAS 73422-04-5C19H21NO4
Cimoxatone, (S)- chemical structure, C19H18N2O4, CAS 73422-40-9
Cimoxatone, (S)-
CAS 73422-40-9C19H18N2O4
Cimoxatone, (R)- chemical structure, C19H18N2O4, CAS 73422-39-6
Cimoxatone, (R)-
CAS 73422-39-6C19H18N2O4
MD 220661 chemical structure, C17H17ClN2O3, CAS 73423-35-5
MD 220661
CAS 73423-35-5C17H17ClN2O3
(R)-3-(4-(Benzyloxy)-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one chemical structure, C17H16FNO4, CAS 790703-49-0
(R)-3-(4-(Benzyloxy)-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one
CAS 790703-49-0C17H16FNO4
3-[4-(Benzyloxy)phenyl]-5-(propoxymethyl)-1,3-oxazolidin-2-one chemical structure, C20H23NO4, CAS 73422-02-3
3-[4-(Benzyloxy)phenyl]-5-(propoxymethyl)-1,3-oxazolidin-2-one
CAS 73422-02-3C20H23NO4
(5R)-3-[4-[(3-Chlorophenyl)methoxy]phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one chemical structure, C17H16ClNO4, CAS 87823-53-8
(5R)-3-[4-[(3-Chlorophenyl)methoxy]phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one
CAS 87823-53-8C17H16ClNO4