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Murcko scaffold

2-Phenyl-2-oxazoline scaffold

392 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
392
With full pages
28
Scaffold SMILES

c1ccc(C2=NCCO2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-2-oxazoline page
Murcko scaffold c1ccc(C2=NCCO2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 392 chemicals

Phenol oxazoline chemical structure, C9H9NO2, CAS 81428-58-2
Phenol oxazoline
CAS 81428-58-2C9H9NO2
Oxazole, 2-(4-fluorophenyl)-4,5-dihydro-4,4-dimethyl- chemical structure, C11H12FNO, CAS 71171-94-3
Oxazole, 2-(4-fluorophenyl)-4,5-dihydro-4,4-dimethyl-
CAS 71171-94-3C11H12FNO
[2-(3,5-Dichlorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazol-5-yl]methanol chemical structure, C12H13Cl2NO2, CAS 31110-36-8
[2-(3,5-Dichlorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazol-5-yl]methanol
CAS 31110-36-8C12H13Cl2NO2
(4-Methyl-2-phenyl-4,5-dihydro-1,3-oxazol-4-yl)methanol chemical structure, C11H13NO2, CAS 5448-32-8
(4-Methyl-2-phenyl-4,5-dihydro-1,3-oxazol-4-yl)methanol
CAS 5448-32-8C11H13NO2
Oxazole, 2-(4-chlorophenyl)-4,5-dihydro- chemical structure, C9H8ClNO, CAS 7399-68-0
Oxazole, 2-(4-chlorophenyl)-4,5-dihydro-
CAS 7399-68-0C9H8ClNO
2-(4-Nitrophenyl)-4,5-dihydro-1,3-oxazole chemical structure, C9H8N2O3, CAS 7465-63-6
2-(4-Nitrophenyl)-4,5-dihydro-1,3-oxazole
CAS 7465-63-6C9H8N2O3
2-Phenyl-2-oxazoline chemical structure, C9H9NO, CAS 7127-19-7
2-Phenyl-2-oxazoline
CAS 7127-19-7C9H9NO
5-Methyl-2-(3-nitrophenyl)-4,5-dihydro-1,3-oxazole chemical structure, C10H10N2O3, CAS 6943-63-1
5-Methyl-2-(3-nitrophenyl)-4,5-dihydro-1,3-oxazole
CAS 6943-63-1C10H10N2O3
5-Methyl-2-(4-nitrophenyl)-4,5-dihydro-1,3-oxazole chemical structure, C10H10N2O3, CAS 6943-64-2
5-Methyl-2-(4-nitrophenyl)-4,5-dihydro-1,3-oxazole
CAS 6943-64-2C10H10N2O3
RefChem:357180 chemical structure, C10H11NO, CAS 23437-02-7
RefChem:357180
CAS 23437-02-7C10H11NO
4,4-Bis(hydroxymethyl)-2-phenyl-2-oxazoline chemical structure, C11H13NO3, CAS 62203-32-1
4,4-Bis(hydroxymethyl)-2-phenyl-2-oxazoline
CAS 62203-32-1C11H13NO3
4,4-Dimethyl-2-phenyl-2-oxazoline chemical structure, C11H13NO, CAS 19312-06-2
4,4-Dimethyl-2-phenyl-2-oxazoline
CAS 19312-06-2C11H13NO
2-(2-Bromophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole chemical structure, C11H12BrNO, CAS 32664-13-4
2-(2-Bromophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole
CAS 32664-13-4C11H12BrNO
5,5-Dimethyl-2-(4-nitrophenyl)-4,5-dihydro-1,3-oxazole chemical structure, C11H12N2O3, CAS 10316-85-5
5,5-Dimethyl-2-(4-nitrophenyl)-4,5-dihydro-1,3-oxazole
CAS 10316-85-5C11H12N2O3
2-Oxazoline, 2-(3,4,5-trimethoxyphenyl)- chemical structure, C12H15NO4, CAS 101932-46-1
2-Oxazoline, 2-(3,4,5-trimethoxyphenyl)-
CAS 101932-46-1C12H15NO4
2-(4-(tert-Butyl)phenyl)-4,4-dimethyl-4,5-dihydrooxazole chemical structure, C15H21NO, CAS 150943-13-8
2-(4-(tert-Butyl)phenyl)-4,4-dimethyl-4,5-dihydrooxazole
CAS 150943-13-8C15H21NO
4,4-Dimethyl-2-(2-methoxyphenyl)oxazoline chemical structure, C12H15NO2, CAS 57598-33-1
4,4-Dimethyl-2-(2-methoxyphenyl)oxazoline
CAS 57598-33-1C12H15NO2
(2-Phenyl-4,5-dihydro-1,3-oxazol-4-yl)methanol chemical structure, C10H11NO2, CAS 15263-48-6
(2-Phenyl-4,5-dihydro-1,3-oxazol-4-yl)methanol
CAS 15263-48-6C10H11NO2
2-(4-Methoxy-3-methylphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole chemical structure, C13H17NO2, CAS 82045-51-0
2-(4-Methoxy-3-methylphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole
CAS 82045-51-0C13H17NO2
1-[2-(4,4-Dimethyl-5H-1,3-oxazol-2-yl)-5-methoxy-4-methylphenyl]ethanone chemical structure, C15H19NO3, CAS 82045-52-1
1-[2-(4,4-Dimethyl-5H-1,3-oxazol-2-yl)-5-methoxy-4-methylphenyl]ethanone
CAS 82045-52-1C15H19NO3
4-(Methoxymethyl)-5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole chemical structure, C12H15NO2, CAS 7462-48-8
4-(Methoxymethyl)-5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole
CAS 7462-48-8C12H15NO2
(5-Methyl-2-phenyl-4,5-dihydro-1,3-oxazol-4-yl)methanol chemical structure, C11H13NO2, CAS 7462-57-9
(5-Methyl-2-phenyl-4,5-dihydro-1,3-oxazol-4-yl)methanol
CAS 7462-57-9C11H13NO2
Ethyl 5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxylate chemical structure, C13H15NO3, CAS 7462-66-0
Ethyl 5-methyl-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxylate
CAS 7462-66-0C13H15NO3
2-(3-Nitrophenyl)-4,5-dihydro-1,3-oxazole chemical structure, C9H8N2O3, CAS 88186-35-0
2-(3-Nitrophenyl)-4,5-dihydro-1,3-oxazole
CAS 88186-35-0C9H8N2O3