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Impurities and reference standards

6-Dehydrocortisol

Also known as Hydrocortisone EP Impurity E, Delta6-Hydrocortisone, Hydrocortisone impurity E

CAS 600-99-7Formula C21H28O5Molar mass 360.45 g/molEC 641-850-8
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard
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6-Dehydrocortisol chemical structure, C21H28O5, CAS 600-99-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
600-99-7
Formula
C21H28O5
Molar mass
360.45 g/mol
EC number
641-850-8
HS code
291440
Category
Impurities and reference standards

What is 6-Dehydrocortisol?

Plain description, key identifiers and synonyms

6-Dehydrocortisol is a chemical substance with the molecular formula C21H28O5 and a molar mass of 360.45 g/mol. Its CAS registry number is 600-99-7. The IUPAC name is (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
CAS number
600-99-7 CAS number cross-checked
EC number
641-850-8
Molecular formula
C21H28O5
UNII
RB1E84M01G
InChIKey
IFOXVSBZLASBJM-VWUMJDOOSA-N
InChI
InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h3-4,9,14-16,18,22,24,26H,5-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
Canonical SMILES
CC12CCC(=O)C=C1C=CC1C2C(O)CC2(C)C1CCC2(O)C(=O)CO
Isomeric SMILES
C[C@]12CCC(=O)C=C1C=C[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O

Synonyms

  • Hydrocortisone EP Impurity E
  • Delta6-Hydrocortisone
  • Hydrocortisone impurity E
  • (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
  • 11beta,17,21-Trihydroxypregna-4,6-diene-3,20-dione
  • Pregna-4,6-diene-3,20-dione, 11beta,17,21-trihydroxy-
  • Pregna-4,6-diene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-
  • 11,17,21-trihydroxypregna-4,6-diene-3,20-dione
  • 11|A,17,21-Trihydroxypregna-4,6-diene-3,20-dione
  • 11?,17,21-Trihydroxypregna-4,6-diene-3,20-dione (?6-Hydrocortisone)
  • 11beta,17,21-Trihydroxypregna-4,6-diene-3,20-dione (?6-Hydrocortisone)
  • Pregna-4,6-diene-3,20-dione, 11,17,21-trihydroxy-, (11.beta.)-
  • (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
360.45 g/molcalc.
Exact mass
360.1937 Dacalc.
LogP (octanol/water)
1.56calc.
Topological polar surface area
94.83 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
2calc.
Heavy atoms
26calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.71calc.
Formal charge
0calc.
Stereocentres
7calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=C2C=CC3C4CCCC4CCC3C2CC1

O=C1C=C2C=CC3C4CCCC4CCC3C2CC1

4 rings, 18 atoms.

106 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H341Suspected of causing genetic defects.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (9)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

6-Dehydrocortisol suppliers

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6-Dehydrocortisol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 6-Dehydrocortisol is traded under.

HS 2914.40Indicative HS code

Ketone-alcohols and ketone-aldehydes

World exports in 2024
$199M
+2.5% vs 2023, imports $247M
2019 to 2024
Top exporters
  1. China29.5%
  2. Germany14.4%
  3. Netherlands12.7%
Top importers
  1. United States37.2%
  2. Netherlands8.5%
  3. Germany6.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for 6-Dehydrocortisol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 6-Dehydrocortisol, based on the data on this page

What is 6-Dehydrocortisol?

6-Dehydrocortisol is a chemical substance with the molecular formula C21H28O5 and a molar mass of 360.45 g/mol. Its CAS registry number is 600-99-7. The IUPAC name is (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one.

What is the CAS number of 6-Dehydrocortisol?

The CAS registry number of 6-Dehydrocortisol is 600-99-7.

What is the molecular formula and weight of 6-Dehydrocortisol?

The molecular formula of 6-Dehydrocortisol is C21H28O5 and its molar mass is 360.45 g/mol.

Is 6-Dehydrocortisol hazardous?

6-Dehydrocortisol carries the GHS signal word "Warning". Main hazards: harmful if swallowed, suspected of causing genetic defects, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 6-Dehydrocortisol?

6-Dehydrocortisol is usually classified under HS code 291440 (Ketone-alcohols and ketone-aldehydes). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 6-Dehydrocortisol?

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What is the price of 6-Dehydrocortisol?

Suppliers quote 6-Dehydrocortisol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 6-Dehydrocortisol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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