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Steroids and sterols

Aldosterone

Also known as (+)-Aldosterone, Aldosterona, Aldosteronum

CAS 52-39-1Formula C21H28O5Molar mass 360.45 g/molEC 200-139-9
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Aldosterone chemical structure, C21H28O5, CAS 52-39-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
52-39-1
Formula
C21H28O5
Molar mass
360.45 g/mol
EC number
200-139-9
HS code
293729
Category
Steroids and sterols

What is Aldosterone?

Plain description, key identifiers and synonyms

Aldosterone is a pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. It has a role as a mouse metabolite and a human metabolite. It is a steroid aldehyde, a primary alpha-hydroxy ketone, a mineralocorticoid, a 21-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a 18-oxo steroid, a 3-oxo-Delta(4) steroid and a C21-steroid hormone. It derives from a hydride of a pregnane.

Aldosterone is a hormone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-13-carbaldehyde
CAS number
52-39-1 CAS number cross-checked
EC number
200-139-9
Molecular formula
C21H28O5
UNII
4964P6T9RB
MDL number
MFCD00051136
InChIKey
PQSUYGKTWSAVDQ-ZVIOFETBSA-N
InChI
InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1
Canonical SMILES
CC12CCC(=O)C=C1CCC1C2C(O)CC2(C=O)C(C(=O)CO)CCC12
Isomeric SMILES
C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C=O)O

Synonyms

  • (+)-Aldosterone
  • Aldosterona
  • Aldosteronum
  • 11beta,21-Dihydroxy-3,20-diketo-4-pregnen-18-al
  • 11beta,21-Dihydroxypregn-4-ene-3,18,20-trione
  • (11Beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al
  • 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al
  • (8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-13-carbaldehyde
  • 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al
  • 11beta,21-dihydroxy-3,20-dioxo-pregn-4-ene-18-al
  • (8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta(a)phenanthrene-13-carbaldehyde
  • (2R,14S,15R,17S)-17-hydroxy-14-(2-hydroxyacetyl)-2-methyl-5-oxotetracyclo(8.7.0.02,7.011,15)heptadec-6-ene-15-carbaldehyde
  • Aldocortin
  • Electrocortin
  • Aldocortene
  • Aldocorten
  • Elektrocortin
  • d-Aldosterone
  • Reichstein X
  • 18-Oxocorticosterone
  • [3H]aldosterone
  • 11beta,21-Dihydroxy-3,20-diketopregn-4-ene-18-al
  • 18-Formyl-11beta,21-dihydroxy-4-pregnene-3,20-dione
  • Pregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11b)-
  • Aldosterone (Standard)
Show all 32 synonyms
  • 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al, 18,11-halbacetal
  • Aldosterone (INN)
  • [3H]-aldosterone
  • Aldosterone (Hemiacetal) (1.0mg/mL in Acetonitrile)
  • delta-Aldosterone
  • Aldosterone standard
  • 11,21-Dihydroxy-3,20-dioxopregn-4-en-18-al

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
360.45 g/molcalc.
Exact mass
360.1937 Dacalc.
LogP (octanol/water)
1.85calc.
Topological polar surface area
91.67 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
3calc.
Heavy atoms
26calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.76calc.
Formal charge
0calc.
Stereocentres
7calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=C2CCC3C4CCCC4CCC3C2CC1

O=C1C=C2CCC3C4CCCC4CCC3C2CC1

4 rings, 18 atoms.

1,419 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Aldosterone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 49 suppliers
30 of 30 offers

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Where suppliers are based

49 suppliers in 10 countries

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Aldosterone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • animal metabolite
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite

Pharmacology

Aldosterone is a mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona glomerulosa of the adrenal cortex. Aldosterone binds to mineralocorticoid receptors (MR, NR3C2) and MR-aldosterone complexes regulate the expression of genes involved in the retention of sodium, the secretion of potassium, and water reabsorption, all of which may result increased blood pressure.

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Aldosterone is traded under.

HS 2937.29Indicative HS code

Steroidal hormones, their derivatives and structural analogues, other

World exports in 2024
$2.32B
+5.7% vs 2023, imports $2.41B
2019 to 2024
Top exporters
  1. Belgium25.3%
  2. United States24.9%
  3. China13.0%
Top importers
  1. Italy18.0%
  2. Canada13.0%
  3. Belgium12.2%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Aldosterone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Aldosterone, based on the data on this page

What is Aldosterone?

Aldosterone is a pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pr…

What is the CAS number of Aldosterone?

The CAS registry number of Aldosterone is 52-39-1.

What is the molecular formula and weight of Aldosterone?

The molecular formula of Aldosterone is C21H28O5 and its molar mass is 360.45 g/mol.

What is Aldosterone used for?

Known uses and roles of Aldosterone include animal metabolite, eukaryotic metabolite, human metabolite, mammalian metabolite, metabolite and 1 more.

Is Aldosterone hazardous?

No GHS hazard classification for Aldosterone is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Aldosterone?

Aldosterone is usually classified under HS code 293729 (Steroidal hormones, their derivatives and structural analogues, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Aldosterone?

CompoundList lists 49 suppliers of Aldosterone in United States, China, Germany, Spain and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Aldosterone?

Suppliers quote Aldosterone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Aldosterone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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