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Insecticides and acaricides

Anabasine

Also known as (-)-Anabasine, (S)-anabasine, Neonicotine

CAS 494-52-0Formula C10H14N2Molar mass 162.24 g/molEC 207-791-3
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant, Serious health hazard, Hazardous to the environment 18 suppliers listed
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Anabasine chemical structure, C10H14N2, CAS 494-52-0
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless liquid, darkens on exposure to air
Melting point
9 °C
Boiling point
270 to 272
Density
1.0455 @ 20 °C/4 °C
Solubility
Miscible in water @ 25 °C
HS code
293979
Category
Insecticides and acaricides
Illustrative photo, clear liquid in sealed glass ampoules on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Anabasine?

Plain description, key identifiers and synonyms

(S)-anabasine is the (S)-enantiomer of anabasine.

Anabasine is a chemical piperidine compound often used as a botanical insecticide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-[(2S)-piperidin-2-yl]pyridine
CAS number
494-52-0 CAS number cross-checked
EC number
207-791-3
Molecular formula
C10H14N2
UNII
LMS11II2LO
MDL number
MFCD00871391
InChIKey
MTXSIJUGVMTTMU-JTQLQIEISA-N
InChI
InChI=1S/C10H14N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h3-4,6,8,10,12H,1-2,5,7H2/t10-/m0/s1
Canonical SMILES
c1cncc(C2CCCCN2)c1
Isomeric SMILES
C1CCN[C@@H](C1)C2=CN=CC=C2

Synonyms

  • (-)-Anabasine
  • (S)-anabasine
  • Neonicotine
  • Neonikotin
  • Anabasin
  • S-(-)-Anabasine
  • 3-[(2S)-piperidin-2-yl]pyridine
  • Anabazin
  • L-3-(2'-Piperidyl)pyridine
  • Piperidine, 2-(3-pyridyl)-
  • (-)-2-(3'-Pyridyl)piperidine
  • Pyridine, 3-(2-piperidinyl)-, (S)-
  • Pyridine, 3-(2S)-2-piperidinyl-
  • Pyridine, 3-(2-piperidyl)-
  • 3-(2-Piperidinyl)pyridine
  • 2-(3'-Pyridyl) piperidine
  • Pyridine, 3-(2-pyridyl) piperidine
  • (S)-3-(2-Piperidinyl)pyridine
  • 3-((2S)-piperidin-2-yl)pyridine
  • 3-(piperidin-2-yl)pyridine
  • (S)-3-(Piperidin-2-yl)pyridine
  • 3-(2S)-2-Piperidinylpyridine
  • Nicotine EP Impurity G
  • (S)-(-)-Anabasine
  • 3-[(2S)-2-piperidyl]pyridine
Show all 33 synonyms
  • (S)-Anabasine, > 98% ee
  • 2-(3-Pyridinyl)piperidine #
  • 3-(2S)-2-Piperidinyl-pyridine
  • (S)-Snabasine
  • Anabasine (Standard)
  • Tocris-1971
  • (S)-Anabasine (>98%)
  • 5-23-06-00096 (Beilstein Handbook Reference)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless liquid, darkens on exposure to airexp.
Melting point
9 °Cexp.
Boiling point
270 to 272exp.
Density
1.0455 @ 20 °C/4 °Cexp.
Solubility
Miscible in water @ 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
162.24 g/molcalc.
Exact mass
162.1157 Dacalc.
LogP (octanol/water)
1.9calc.
Topological polar surface area
24.92 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
12calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1cncc(C2CCCCN2)c1

c1cncc(C2CCCCN2)c1

2 rings, 12 atoms, the (±)-Anabasine ring system.

420 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H300Fatal if swallowed.
  • H301Toxic if swallowed.
  • H310Fatal in contact with skin.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H361Suspected of damaging fertility or the unborn child.
  • H361fdSuspected of damaging fertility. Suspected of damaging the unborn child.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (21)
  • P203Obtain, read and follow all safety instructions before use.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Anabasine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 18 suppliers
18 of 18 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

18 suppliers in 6 countries

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Anabasine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Anabasine is no longer used as an insecticide in the United States or the United Kingdom.

Pharmacological actions

  • Insecticides

Pharmacology

Anabasine is a nicotine analog that is an alkaloid found in tree tobacco (Nicotiana glauca) and is comprised of a pyridine substituted by a piperidin-2-yl group at position 3. Anabasine has been used as an industrial insecticide and, since it is present in trace amounts in tobacco smoke, its detection in urine can be used as an indicator of exposure to tobacco smoke.

How it is made

Extracted on a large scale in Russia. Industrial extraction processes: Sadykov, Timbekov, J Appl Chem USSR 29: 148 (1956).

Derivation: (1) Extraction from Anabasis aphylla and Nicotiana glauca, (2) synthetic

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Anabasine is traded under.

HS 2939.79Indicative HS code

Alkaloids of vegetal origin, other than cocaine, ecgonine, salts, esters and other derivatives, not elsewhere…

World exports in 2024
$701M
+18.9% vs 2023, imports $830M
2019 to 2024
Top exporters
  1. Switzerland * partner reported25.3%
  2. Germany21.4%
  3. India * partner reported14.9%
Top importers
  1. United States20.9%
  2. Germany14.7%
  3. Italy14.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Anabasine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Anabasine, based on the data on this page

What is Anabasine?

(S)-anabasine is the (S)-enantiomer of anabasine.

What is the CAS number of Anabasine?

The CAS registry number of Anabasine is 494-52-0.

What is the molecular formula and weight of Anabasine?

The molecular formula of Anabasine is C10H14N2 and its molar mass is 162.24 g/mol.

What is Anabasine used for?

Anabasine is no longer used as an insecticide in the United States or the United Kingdom.

Is Anabasine hazardous?

Anabasine carries the GHS signal word "Danger". Main hazards: fatal if swallowed, toxic if swallowed, fatal in contact with skin. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Anabasine?

Anabasine is usually classified under HS code 293979 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and other…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Anabasine?

CompoundList lists 18 suppliers of Anabasine in China, United States, India, Czech Republic and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Anabasine in India?

2 suppliers in India list Anabasine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Anabasine?

Suppliers quote Anabasine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Anabasine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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