CompoundList
Sign in
Heterocyclic building blocks

Mazindol

Also known as Mazanor, Sanorex, Mazildene

CAS 22232-71-9Formula C16H13ClN2OMolar mass 284.75 g/molEC 244-857-0
GHS signal word: Danger. Pictograms: Acute toxicity (severe) Prohibited, not for trade
Why it is not for trade
Mazindol chemical structure, C16H13ClN2O, CAS 22232-71-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
White crystalline solid from ethanol crystals from acetone-hexane
Melting point
198 to 199
Solubility
INSOL IN WATER
HS code
293391
Category
Heterocyclic building blocks

What is Mazindol?

Plain description, key identifiers and synonyms

Mazindol is an organic molecular entity.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol
CAS number
22232-71-9 CAS number cross-checked
EC number
244-857-0
Molecular formula
C16H13ClN2O
UNII
C56709M5NH
MDL number
MFCD00864480
InChIKey
ZPXSCAKFGYXMGA-UHFFFAOYSA-N
InChI
InChI=1S/C16H13ClN2O/c17-12-7-5-11(6-8-12)16(20)14-4-2-1-3-13(14)15-18-9-10-19(15)16/h1-8,20H,9-10H2
SMILES (canonical and isomeric)
C1CN2C(=N1)C3=CC=CC=C3C2(C4=CC=C(C=C4)Cl)O

Synonyms

  • Mazanor
  • Sanorex
  • Mazildene
  • Teronac
  • Magrilon
  • Dimagrir
  • Terenac
  • Mazindole
  • Mazindolum
  • AN 448
  • Mazindol civ
  • SAH 42548
  • SA 42-548
  • 5-p-Chlorophenyl-2,3-dihydro-5H-imidazo(2,1-a)isoindol-5-ol
  • 3H-Imidazo(2,1-a)isoindol-5-ol, 5-(4-chlorophenyl)-2,5-dihydro-
  • 5H-Imidazo(2,1-a)isoindol-5-ol, 5-(4-chlorophenyl)-2,3-dihydro
  • Sanjorex
  • Teronak
  • 3H-Imidazo(2,1-a)isoindol-5-ol, 5-(p-chlorophenyl)-2,5-dihydro-
  • 3H-Imidazo[2,1-a]isoindol-5-ol, 5-(4-chlorophenyl)-2,5-dihydro-
  • 5-(4-chlorophenyl)-2H,3H,5H-imidazo[2,1-a]isoindol-5-ol
  • 3H-Imidazo[2,1-a]isoindol-5-ol, 5-(p-chlorophenyl)-2,5-dihydro-
  • Mazindolo
  • 5-(4-chlorophenyl)-2H,3H,5H-imidazo(2,1-a)isoindol-5-ol
  • 5-(4-chlorophenyl)-2,3-dihydroimidazo[1,2-b]isoindol-5-ol
Show all 36 synonyms
  • 5-(4-Chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol
  • 5-(4-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
  • 5-(4-Chlorophenyl)-2,3-dihydro-5-hydroxy-5H-imidazo[2,1-a]isoindole
  • 5-(p-Chlorophenyl)-2,5-dihydro-3H-imidazo(2,1-a)isoindol-5-ol
  • 5-(4-Chlorophenyl)-2,3-dihydro-5-hydroxy-5H-imidazo(2,1-a)isoindole
  • Mazindol (1mg/ml in Acetonitrile)
  • Mazindol (1.0 mg/mL in Methanol)
  • [3H]-mazindol
  • DEA No. 1605
  • [3H]mazindol
  • Sanorex (tn)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White crystalline solid from ethanol crystals from acetone-hexaneexp.
Odour
FAINT ODOR TO ODORLESSexp.
Melting point
198 to 199exp.
Solubility
INSOL IN WATERexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
284.75 g/molcalc.
Exact mass
284.0716 Dacalc.
LogP (octanol/water)
2.61calc.
Topological polar surface area
35.83 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
1calc.
Heavy atoms
20calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.19calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(C2c3ccccc3C3=NCCN32)cc1

c1ccc(C2c3ccccc3C3=NCCN32)cc1

4 rings, 18 atoms.

17 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H300Fatal if swallowed.
  • H311Toxic in contact with skin.
  • H331Toxic if inhaled.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Mazindol suppliers

Trading restrictions apply to this substance

Psychotropic substance

Mazindol is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2933.91 (benzodiazepines and related substances)

Our policy on controlled substances

Mazindol price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Therapeutic category: anorexic, CNS stimulant (Former).

Appetite suppressant (Former).

Use classes: Pharmaceuticals.

Pharmacological actions

  • Adrenergic Uptake Inhibitors
  • Central Nervous System Stimulants
  • Dopamine Uptake Inhibitors

Roles

  • anti-obesity agent

How it is made

Preparation: W.J. Houlihan, DE 1814540, W.J. Houlihan, M.K. Eberle, DE 1930488, eidem US 3597445 (1969, 1970, 1970 all to Sandoz)

Preperation: T.S. Sulkowski, US 3763178 (1973 to American Home Prod.)

Mazindol is prepared by treating the dilithio reagent, obtained from 2-phenylimidazoline, with methyl 4-chlorobenzoate.

Regulatory status

Inventories, regulations and trade controls that list this substance

Psychotropic substance

Mazindol is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2933.91 (benzodiazepines and related substances)

Our policy on controlled substances

Controls

  • US DEA controlled substance or listed chemical
  • Controlled psychotropic substance

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Mazindol is traded under.

HS 2933.91Exact HS code

Alprazolam (INN), camazepam (INN), chlordiazepoxide (INN), clonazepam (INN)…

World exports in 2024
$118M
−26.3% vs 2023, imports $94.2M
2019 to 2024
Top exporters
  1. Italy37.7%
  2. United States22.7%
  3. India * partner reported9.8%
Top importers
  1. Germany13.8%
  2. Spain10.4%
  3. United States10.2%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Mazindol is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Mazindol, based on the data on this page

What is Mazindol?

Mazindol is an organic molecular entity.

What is the CAS number of Mazindol?

The CAS registry number of Mazindol is 22232-71-9.

What is the molecular formula and weight of Mazindol?

The molecular formula of Mazindol is C16H13ClN2O and its molar mass is 284.75 g/mol.

What is Mazindol used for?

Therapeutic category: anorexic, CNS stimulant (Former). Appetite suppressant (Former). Use classes: Pharmaceuticals.

Is Mazindol hazardous?

Mazindol carries the GHS signal word "Danger". Main hazards: fatal if swallowed, toxic in contact with skin, toxic if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Mazindol?

Mazindol is usually classified under HS code 293391 (Alprazolam (INN), camazepam (INN), chlordiazepoxide (INN), clonazepam (INN)…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Mazindol on CompoundList?

No. Mazindol is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Mazindol

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

Explore more in Heterocyclic building blocks or HS code 293391

Not available for trade
Why