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Impurities and reference standards

Norcodeine

Also known as N-Desmethylcodeine, Norcodeina, N-Demethylcodeine

CAS 467-15-2Formula C17H19NO3Molar mass 285.34 g/molEC 207-388-2
GHS signal word: Warning. Pictograms: Harmful or irritant 1 supplier listed
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Norcodeine chemical structure, C17H19NO3, CAS 467-15-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
467-15-2
Formula
C17H19NO3
Molar mass
285.34 g/mol
EC number
207-388-2
HS code
293499
Category
Impurities and reference standards

What is Norcodeine?

Plain description, key identifiers and synonyms

Norcodeine is a morphinane-like compound that is the N-demethylated derivative of codeine. It is functionally related to a codeine.

Norcodeine is a morphinane-like compound, N-demethylated derivative of codeine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(4R,4aR,7S,7aR,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
CAS number
467-15-2 CAS number cross-checked
EC number
207-388-2
Molecular formula
C17H19NO3
UNII
32W9P3T4ML
InChIKey
HKOIXWVRNLGFOR-KOFBORESSA-N
InChI
InChI=1S/C17H19NO3/c1-20-13-5-2-9-8-11-10-3-4-12(19)16-17(10,6-7-18-11)14(9)15(13)21-16/h2-5,10-12,16,18-19H,6-8H2,1H3/t10-,11+,12-,16-,17-/m0/s1
Canonical SMILES
COc1ccc2c3c1OC1C(O)C=CC4C(C2)NCCC341
Isomeric SMILES
COC1=C2C3=C(C[C@@H]4[C@H]5[C@]3(CCN4)[C@@H](O2)[C@H](C=C5)O)C=C1

Synonyms

  • N-Desmethylcodeine
  • Norcodeina
  • N-Demethylcodeine
  • Norcodeinum
  • (-)-N-Norcodeine
  • Normorphine 3-methyl ether
  • 3-o-methylnormorphine
  • IDS-NN-005(SECT.2)
  • (4R,4aR,7S,7aR,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
  • (4R,4aR,7S,7aR,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro(3,2-e)isoquinolin-7-ol
  • (4R,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro(3,2-e)isoquinoline-7-ol
  • (4R,4aR,7S,7aR,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro(3,2-e)isoquinoline-7-ol
  • (-)-Norcodeine
  • Norcodeine, 1mg/ml in Methanol
  • 7,8-Didehydro-4,5-alpha-epoxy-3-methoxymorphinan-6-alpha-ol
  • Norcodeine 1.0 mg/ml in Methanol
  • Norcodeine (stereochemistry defined)
  • Codeine monohydrate impurity h
  • 3-methoxy-7,8-didehydro-4,5alpha-epoxymorphinan-6alpha-ol
  • 3-Methoxy-5alpha-7,8-didehydro-4,5-epoxymorphinan-6alpha-ol
  • Codeine hydrochloride dihydrate impurity h
  • Codeine phosphate hemihydrate impurity h
  • Morphinan-6-alpha-ol, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-
  • Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-, (5-alpha,6-alpha)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
285.34 g/molcalc.
Exact mass
285.1365 Dacalc.
LogP (octanol/water)
1.16calc.
Topological polar surface area
50.72 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
1calc.
Heavy atoms
21calc.
Rings
5calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.53calc.
Formal charge
0calc.
Stereocentres
5calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=CC2C3Cc4cccc5c4C2(CCN3)C(C1)O5

C1=CC2C3Cc4cccc5c4C2(CCN3)C(C1)O5

5 rings, 18 atoms.

246 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H336May cause drowsiness or dizziness.
Precautionary statements (11)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P301 + P317If swallowed: Get medical help.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P319Get medical help if you feel unwell.
  • P330Rinse mouth.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Norcodeine suppliers

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  • Veeprho
    Czech Republic, Czech RepublicUnclaimed profile
    NorcodeineGrade, purity and minimum order on request
    Price on request
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Where suppliers are based

1 supplier in 1 country

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Norcodeine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Norcodeine is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Norcodeine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Norcodeine, based on the data on this page

What is Norcodeine?

Norcodeine is a morphinane-like compound that is the N-demethylated derivative of codeine. It is functionally related to a codeine.

What is the CAS number of Norcodeine?

The CAS registry number of Norcodeine is 467-15-2.

What is the molecular formula and weight of Norcodeine?

The molecular formula of Norcodeine is C17H19NO3 and its molar mass is 285.34 g/mol.

Is Norcodeine hazardous?

Norcodeine carries the GHS signal word "Warning". Main hazards: harmful if swallowed, may cause drowsiness or dizziness. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Norcodeine?

Norcodeine is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Norcodeine?

CompoundList lists 1 supplier of Norcodeine in Czech Republic. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Norcodeine?

Suppliers quote Norcodeine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Norcodeine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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