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Heterocyclic building blocks

Normorphine

Also known as Desmethylmorphine, (-)-Normorphine, Normorfina

CAS 466-97-7Formula C16H17NO3Molar mass 271.32 g/molEC 207-381-4
GHS signal word: Danger. Pictograms: Acute toxicity (severe) 1 supplier listed
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Normorphine chemical structure, C16H17NO3, CAS 466-97-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
466-97-7
Formula
C16H17NO3
Molar mass
271.32 g/mol
EC number
207-381-4
HS code
293499
Category
Heterocyclic building blocks

What is Normorphine?

Plain description, key identifiers and synonyms

Normorphine is a morphinane alkaloid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(4R,4aR,7S,7aR,12bS)-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
CAS number
466-97-7 CAS number cross-checked
EC number
207-381-4
Molecular formula
C16H17NO3
UNII
XUI1Y24IMI
InChIKey
ONBWJWYUHXVEJS-ZTYRTETDSA-N
InChI
InChI=1S/C16H17NO3/c18-11-3-1-8-7-10-9-2-4-12(19)15-16(9,5-6-17-10)13(8)14(11)20-15/h1-4,9-10,12,15,17-19H,5-7H2/t9-,10+,12-,15-,16-/m0/s1
Canonical SMILES
Oc1ccc2c3c1OC1C(O)C=CC4C(C2)NCCC341
Isomeric SMILES
C1CN[C@@H]2CC3=C4[C@@]15[C@H]2C=C[C@@H]([C@@H]5OC4=C(C=C3)O)O

Synonyms

  • Desmethylmorphine
  • (-)-Normorphine
  • Normorfina
  • N-Demethylmorphine
  • Normorphinum
  • DEA No. 9313
  • 4,5-Epoxy-3,6-dihydroxymorphin-7-ene
  • Morphinan-3,6alpha-diol, 7,8-didehydro-4,5alpha-epoxy-
  • (4R,4aR,7S,7aR,12bS)-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro(3,2-e)isoquinoline-7,9-diol
  • (4R,4aR,7S,7aR,12bS)-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
  • 4R,4aR,7S,7aR,12bS)-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro(3,2-e)isoquinoline-7,9-diol
  • 4R,4aR,7S,7aR,12bS)-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
  • 1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro(3,2-e)isoquinoline-7,9-diol
  • N-Normorphine
  • Normorphine (1mg/ml in Methanol)
  • Normorphine (7,8-Didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol)
  • Normorphine 1.0 mg/ml in Methanol
  • 7,8-Didehydro-4,5alpha-epoxy-Morphinan-3,6alpha-diol
  • Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-
  • Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-, (5alpha,6alpha)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
271.32 g/molcalc.
Exact mass
271.1208 Dacalc.
LogP (octanol/water)
0.86calc.
Topological polar surface area
61.72 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
0calc.
Heavy atoms
20calc.
Rings
5calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
5calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=CC2C3Cc4cccc5c4C2(CCN3)C(C1)O5

C1=CC2C3Cc4cccc5c4C2(CCN3)C(C1)O5

5 rings, 18 atoms.

246 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H300Fatal if swallowed.
  • H310Fatal in contact with skin.
  • H330Fatal if inhaled.
Precautionary statements (18)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Normorphine suppliers

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Where suppliers are based

1 supplier in 1 country

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Normorphine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

Controls

  • US DEA controlled substance or listed chemical

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Normorphine is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Normorphine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Normorphine, based on the data on this page

What is Normorphine?

Normorphine is a morphinane alkaloid.

What is the CAS number of Normorphine?

The CAS registry number of Normorphine is 466-97-7.

What is the molecular formula and weight of Normorphine?

The molecular formula of Normorphine is C16H17NO3 and its molar mass is 271.32 g/mol.

What is Normorphine used for?

Known uses and roles of Normorphine include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Normorphine hazardous?

Normorphine carries the GHS signal word "Danger". Main hazards: fatal if swallowed, fatal in contact with skin, fatal if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Normorphine?

Normorphine is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Normorphine?

CompoundList lists 1 supplier of Normorphine in United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Normorphine?

Suppliers quote Normorphine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Normorphine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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