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Central nervous system drugs

Perazine

Also known as Pernazine, N-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazine, 10-(3-(4-Methylpiperazin-1-yl)propyl)-10H-phenothiazine

CAS 84-97-9Formula C20H25N3SMolar mass 339.51 g/molEC 201-578-9
GHS signal word: Warning. Pictograms: Harmful or irritant 1 supplier listed
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Perazine chemical structure, C20H25N3S, CAS 84-97-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
84-97-9
Formula
C20H25N3S
Molar mass
339.51 g/mol
EC number
201-578-9
HS code
293430
Category
Central nervous system drugs

What is Perazine?

Plain description, key identifiers and synonyms

Perazine is a phenothiazine derivative in which 10H-phenothiazinecarries a 3-(4-methylpiperazin-1-yl)propyl substituent at the N-10 position. It has a role as a phenothiazine antipsychotic drug and a dopaminergic antagonist. It is a member of phenothiazines, a N-alkylpiperazine and a N-methylpiperazine. It derives from a hydride of a 10H-phenothiazine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
CAS number
84-97-9 CAS number cross-checked
EC number
201-578-9
Molecular formula
C20H25N3S
UNII
8915147A2B
InChIKey
WEYVCQFUGFRXOM-UHFFFAOYSA-N
InChI
InChI=1S/C20H25N3S/c1-21-13-15-22(16-14-21)11-6-12-23-17-7-2-4-9-19(17)24-20-10-5-3-8-18(20)23/h2-5,7-10H,6,11-16H2,1H3
SMILES (canonical and isomeric)
CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=CC=CC=C42

Synonyms

  • Pernazine
  • N-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazine
  • 10-(3-(4-Methylpiperazin-1-yl)propyl)-10H-phenothiazine
  • N-Methyl-piperazinyl-N'-propyl-phenothiazin
  • 10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
  • 10H-Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-
  • 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-
  • Dihydrochloride, Perazine
  • Maleate, Perazine
  • Psytomin
  • Taxilan
  • 10-(3-(4-Methyl-1-piperazinyl)propyl)-10H-phenothiazine
  • 10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
  • Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-
  • N-Methyl-piperazinylpropyl-phenothiazine
  • 10-(3-(4-methylpiperazin-1-yl)propyl)phenothiazine
  • Perazin
  • Prochlorperazine RC 4
  • N-Methyl-piperazinyl-N'-propyl-phenothiazine
  • US9504692, 3946
  • Prochlorperazine maleate impurity b

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
339.51 g/molcalc.
Exact mass
339.1769 Dacalc.
LogP (octanol/water)
3.93calc.
Topological polar surface area
9.72 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
24calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)Sc1ccccc1N2CCCN1CCNCC1

c1ccc2c(c1)Sc1ccccc1N2CCCN1CCNCC1

4 rings, 23 atoms, the 10-Piperazinylpropylphenothiazine ring system.

206 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H332Harmful if inhaled.
Precautionary statements (9)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P301 + P317If swallowed: Get medical help.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Perazine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

See the supplier
  • Veeprho
    Czech Republic, Czech RepublicUnclaimed profile
    PerazineGrade, purity and minimum order on request
    Price on request
    View

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Where suppliers are based

1 supplier in 1 country

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Perazine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Pharmacological actions

  • Antipsychotic Agents
  • Dopamine Antagonists

Roles

  • antagonist
  • antidepressant
  • antipsychotic agent
  • anxiolytic drug
  • central nervous system depressant
  • central nervous system drug
  • dopaminergic agent
  • dopaminergic antagonist
  • first generation antipsychotic
  • neurotransmitter agent
  • pharmaceutical
  • phenothiazine antipsychotic drug
  • psychotropic drug
  • tranquilizing drug

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Perazine is traded under.

HS 2934.30Indicative HS code

Compounds containing in the structure a phenothiazine ring-system (whether or not…

World exports in 2024
$89.3M
−7.1% vs 2023, imports $97M
2019 to 2024
Top exporters
  1. Germany21.6%
  2. France * partner reported14.6%
  3. China13.0%
Top importers
  1. United States14.2%
  2. Brazil12.7%
  3. India * partner reported10.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Perazine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Perazine, based on the data on this page

What is Perazine?

Perazine is a phenothiazine derivative in which 10H-phenothiazinecarries a 3-(4-methylpiperazin-1-yl)propyl substituent at the N-10 position. It has a role as a phenothiazine antipsychotic drug and a dopaminergic antagonist. It is a member of phenothiazines, a N-alkylpiperazine and a N-methylpiperazine.

What is the CAS number of Perazine?

The CAS registry number of Perazine is 84-97-9.

What is the molecular formula and weight of Perazine?

The molecular formula of Perazine is C20H25N3S and its molar mass is 339.51 g/mol.

What is Perazine used for?

Known uses and roles of Perazine include cns agents in pharmaceuticals, antagonist, antidepressant, antipsychotic agent, anxiolytic drug and 12 more.

Is Perazine hazardous?

Perazine carries the GHS signal word "Warning". Main hazards: harmful if swallowed, harmful if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Perazine?

Perazine is usually classified under HS code 293430 (Compounds containing in the structure a phenothiazine ring-system (whether or not…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Perazine?

CompoundList lists 1 supplier of Perazine in Czech Republic. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Perazine?

Suppliers quote Perazine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Perazine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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