Ryuvidine
Also known as Cdk4 Inhibitor III, 2-methyl-5-[(4-methylphenyl)amino]-4,7-dihydro-1,3-benzothiazole-4,7-dione, 2-methyl-5-((4-methylphenyl)amino)-4,7-dihydro-1,3-benzothiazole-4,7-dione
Key facts
What buyers check first
- CAS number
- 265312-55-8
- Formula
- C15H12N2O2S
- Molar mass
- 284.34 g/mol
- HS code
- 293420
- Category
- Heterocyclic building blocks
What is Ryuvidine?
Plain description, key identifiers and synonyms
Ryuvidine is a member of the class of benzothiazoles that is 1,3-benzothiazole-4,7-dione substituted by methyl and (4-methylphenyl)amino groups at positions 2 and 5, respectively. It is an inhibitor of CDK4 and SETD8 and exhibits cytotoxicity towards a number of human cancer cell lines. It has a role as an antineoplastic agent and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is an aminotoluene, a member of p-quinones, a member of benzothiazoles and a secondary amino compound.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 2-methyl-5-(4-methylanilino)-1,3-benzothiazole-4,7-dione
- CAS number
- 265312-55-8
- Molecular formula
- C15H12N2O2S
- UNII
- C4QER4DF5C
- MDL number
- MFCD09971103
- InChIKey
- HFPLHASLIOXVGS-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H12N2O2S/c1-8-3-5-10(6-4-8)17-11-7-12(18)15-13(14(11)19)16-9(2)20-15/h3-7,17H,1-2H3
- SMILES (canonical and isomeric)
- CC1=CC=C(C=C1)NC2=CC(=O)C3=C(C2=O)N=C(S3)C
Synonyms
- Cdk4 Inhibitor III
- 2-methyl-5-[(4-methylphenyl)amino]-4,7-dihydro-1,3-benzothiazole-4,7-dione
- 2-methyl-5-((4-methylphenyl)amino)-4,7-dihydro-1,3-benzothiazole-4,7-dione
- 2-Methyl-5-[(4-methylphenyl)amino]benzothiazole-4,7-dione
- 2-methyl-5-(p-tolylamino)benzo[d]thiazole-4,7-dione
- 2-methyl-5-(4-methylanilino)-1,3-benzothiazole-4,7-dione
- Ryuvidine?
- 2-Methyl-5-[(4-methylphenyl)amino]-4,7-benzothiazoledione
- 5-(N-(4-Methylphenyl)amino)-2-methyl-4,7-dioxobenzothiazole
- 2-Methyl-5-p-tolylamino-benzothiazole-4,7-dione
- Sdccgsbi-0086743.p003
- 4,7-Benzothiazoledione, 2-methyl-5-[(4-methylphenyl)amino]-
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 284.34 g/molcalc.Computed value |
|---|---|
| Exact mass | 284.0619 Dacalc.Computed value |
| LogP (octanol/water) | 3.13calc.Computed value |
| Topological polar surface area | 59.06 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 5calc.Computed value |
| Rotatable bonds | 2calc.Computed value |
| Heavy atoms | 20calc.Computed value |
| Rings | 3calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.13calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=C1C(Nc2ccccc2)=CC(=O)c2scnc21
3 rings, 18 atoms.
No other chemical in our database has this scaffold.
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Ryuvidine suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
Post one free request and suppliers who make or trade Ryuvidine can send you quotes. Your contact details stay private until you accept a quote.
Ryuvidine price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Roles
- antineoplastic agent
- enzyme inhibitor
- pharmaceutical
- protein kinase inhibitor
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Ryuvidine is traded under.
Compounds containing in the structure a benzothiazole ring-system (whether or not…
- China62.9%
- Belgium14.6%
- United States5.4%
- India * partner reported18.5%
- United States18.1%
- Brazil6.7%
* Partner reported figures, a lower bound.
The HS code shown for Ryuvidine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Ryuvidine, based on the data on this page
What is Ryuvidine?
What is the CAS number of Ryuvidine?
What is the molecular formula and weight of Ryuvidine?
What is Ryuvidine used for?
Is Ryuvidine hazardous?
What is the HS code of Ryuvidine?
Where can I buy Ryuvidine?
What is the price of Ryuvidine?
Guides for buyers
Practical guides that help when you source, ship or handle Ryuvidine
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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