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Murcko scaffold

Ring system with 4 rings and 22 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
14
With full pages
8
Scaffold SMILES

O=c1c(-c2cnn(-c3ccccc3)c2)coc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(-c2cnn(-c3ccccc3)c2)coc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

7-Methoxy-2,8-dimethyl-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-4-one chemical structure, C21H18N2O3, CAS 385401-59-2
7-Methoxy-2,8-dimethyl-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-4-one
CAS 385401-59-2C21H18N2O3
7-Methoxy-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-4-one chemical structure, C19H14N2O3, CAS 61034-10-4
7-Methoxy-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-4-one
CAS 61034-10-4C19H14N2O3
2-Methyl-4-oxo-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-7-yl acetate chemical structure, C21H16N2O4, CAS 51411-95-1
2-Methyl-4-oxo-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-7-yl acetate
CAS 51411-95-1C21H16N2O4
7-Methoxy-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one chemical structure, C20H13F3N2O3, CAS 51412-22-7
7-Methoxy-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one
CAS 51412-22-7C20H13F3N2O3
[8-Acetyloxy-4-oxo-3-(1-phenylpyrazol-4-yl)-2-(trifluoromethyl)chromen-7-yl] acetate chemical structure, C23H15F3N2O6, CAS 431070-21-2
[8-Acetyloxy-4-oxo-3-(1-phenylpyrazol-4-yl)-2-(trifluoromethyl)chromen-7-yl] acetate
CAS 431070-21-2C23H15F3N2O6
7,8-Dimethoxy-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one chemical structure, C21H15F3N2O4, CAS 431919-21-0
7,8-Dimethoxy-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one
CAS 431919-21-0C21H15F3N2O4
4-Oxo-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-7-yl acetate chemical structure, C20H14N2O4, CAS 61064-46-8
4-Oxo-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-7-yl acetate
CAS 61064-46-8C20H14N2O4
8-Methyl-4-oxo-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-7-yl acetate chemical structure, C22H15F3N2O4, CAS 385401-13-8
8-Methyl-4-oxo-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-7-yl acetate
CAS 385401-13-8C22H15F3N2O4
4-Oxo-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-7-yl acetate chemical structure, C21H13F3N2O4, CAS 303095-18-3
4-Oxo-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-7-yl acetate
CAS 303095-18-3C21H13F3N2O4
7-Hydroxy-3-(1-phenyl-1H-pyrazol-4-yl)-chromen-4-one chemical structure, C18H12N2O3, CAS 61034-11-5
7-Hydroxy-3-(1-phenyl-1H-pyrazol-4-yl)-chromen-4-one
CAS 61034-11-5C18H12N2O3
6-Ethyl-7-hydroxy-2-methyl-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-4-one chemical structure, C21H18N2O3, CAS 431915-88-7
6-Ethyl-7-hydroxy-2-methyl-3-(1-phenyl-1H-pyrazol-4-yl)-4H-chromen-4-one
CAS 431915-88-7C21H18N2O3
7,8-Dihydroxy-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one chemical structure, C19H11F3N2O4, CAS 431068-08-5
7,8-Dihydroxy-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one
CAS 431068-08-5C19H11F3N2O4
7-Hydroxy-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one chemical structure, C19H11F3N2O3, CAS 51412-01-2
7-Hydroxy-3-(1-phenyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)-4H-chromen-4-one
CAS 51412-01-2C19H11F3N2O3
3-[1-(4-Chlorophenyl)pyrazol-4-yl]-7,8-dihydroxy-2-(trifluoromethyl)chromen-4-one chemical structure, C19H10ClF3N2O4, CAS 2813310-07-3
3-[1-(4-Chlorophenyl)pyrazol-4-yl]-7,8-dihydroxy-2-(trifluoromethyl)chromen-4-one
CAS 2813310-07-3C19H10ClF3N2O4