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Murcko scaffold

Ring system with 4 rings and 22 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
11
With full pages
5
Scaffold SMILES

O=c1oc2ccccc2cc1-c1ccn(-c2ccccc2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1oc2ccccc2cc1-c1ccn(-c2ccccc2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

3-(2-Oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde chemical structure, C19H12N2O3, CAS 103593-79-9
3-(2-Oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde
CAS 103593-79-9C19H12N2O3
3-(2-Oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbonitrile chemical structure, C19H11N3O2, CAS 371773-61-4
3-(2-Oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbonitrile
CAS 371773-61-4C19H11N3O2
3-[3-(2-Oxochromen-3-yl)-1-phenylpyrazol-4-yl]prop-2-enoic acid chemical structure, C21H14N2O4
3-[3-(2-Oxochromen-3-yl)-1-phenylpyrazol-4-yl]prop-2-enoic acid
C21H14N2O4
3-[3-(2-Oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazol-4-yl]prop-2-enoic acid chemical structure, C21H14N2O4, CAS 519137-46-3
3-[3-(2-Oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazol-4-yl]prop-2-enoic acid
CAS 519137-46-3C21H14N2O4
(E)-2-Cyano-3-[3-(2-oxochromen-3-yl)-1-phenylpyrazol-4-yl]prop-2-enamide chemical structure, C22H14N4O3, CAS 380221-96-5
(E)-2-Cyano-3-[3-(2-oxochromen-3-yl)-1-phenylpyrazol-4-yl]prop-2-enamide
CAS 380221-96-5C22H14N4O3
N,N-Dimethyl-3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carboxamide chemical structure, C21H17N3O3, CAS 882228-87-7
N,N-Dimethyl-3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carboxamide
CAS 882228-87-7C21H17N3O3
(Z)-3-[3-(2-Oxochromen-3-yl)-1-phenylpyrazol-4-yl]prop-2-enoic acid chemical structure, C21H14N2O4, CAS 301676-60-8
(Z)-3-[3-(2-Oxochromen-3-yl)-1-phenylpyrazol-4-yl]prop-2-enoic acid
CAS 301676-60-8C21H14N2O4
3-(6-Hydroxy-2-oxochromen-3-yl)-1-phenylpyrazole-4-carbaldehyde chemical structure, C19H12N2O4, CAS 371917-56-5
3-(6-Hydroxy-2-oxochromen-3-yl)-1-phenylpyrazole-4-carbaldehyde
CAS 371917-56-5C19H12N2O4
3-(6-Bromo-2-oxochromen-3-yl)-1-phenylpyrazole-4-carbaldehyde chemical structure, C19H11BrN2O3, CAS 371918-02-4
3-(6-Bromo-2-oxochromen-3-yl)-1-phenylpyrazole-4-carbaldehyde
CAS 371918-02-4C19H11BrN2O3
2-Cyano-N-(3-ethoxypropyl)-3-[3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazol-4-yl]prop-2-enamide chemical structure, C27H24N4O4, CAS 882233-26-3
2-Cyano-N-(3-ethoxypropyl)-3-[3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazol-4-yl]prop-2-enamide
CAS 882233-26-3C27H24N4O4
Ethyl 3-oxo-2-[[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]methylene]butanoate chemical structure, C25H20N2O5, CAS 375394-75-5
Ethyl 3-oxo-2-[[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]methylene]butanoate
CAS 375394-75-5C25H20N2O5