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Murcko scaffold

Ring system with 3 rings and 19 atoms

9 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 19
Chemicals: 9
With full pages: 0

Scaffold SMILES

c1ccc(CC(c2ccccc2)N2CCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(CC(c2ccccc2)N2CCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1-(1,2-Diphenylethyl)pyrrolidine--hydrogen chloride (1/1) chemical structure, C18H22ClN, CAS 1939-35-1

1-(1,2-Diphenylethyl)pyrrolidine--hydrogen chloride (1/1)

CAS 1939-35-1C₁₈H₂₂ClN

1,2-Diphenyl-2-(pyrrolidin-1-yl)ethanol chemical structure, C18H21NO, CAS 17244-79-0

1,2-Diphenyl-2-(pyrrolidin-1-yl)ethanol

CAS 17244-79-0C₁₈H₂₁NO

S-[(1R,2S)-1,2-Diphenyl-2-(pyrrolidin-1-yl)ethyl] ethanethioate chemical structure, C20H23NOS, CAS 571148-37-3

S-[(1R,2S)-1,2-Diphenyl-2-(pyrrolidin-1-yl)ethyl] ethanethioate

CAS 571148-37-3C₂₀H₂₃NOS

1,2-Bis(2-methoxyphenyl)-2-(pyrrolidin-1-yl)ethan-1-ol--hydrogen chloride (1/1) chemical structure, C20H26ClNO3, CAS 5450-18-0

1,2-Bis(2-methoxyphenyl)-2-(pyrrolidin-1-yl)ethan-1-ol--hydrogen chloride (1/1)

CAS 5450-18-0C₂₀H₂₆ClNO₃

(1S,2S)-1,2-Diphenyl-2-(pyrrolidin-1-yl)ethan-1-amine chemical structure, C18H22N2, CAS 1416133-22-6

(1S,2S)-1,2-Diphenyl-2-(pyrrolidin-1-yl)ethan-1-amine

CAS 1416133-22-6C₁₈H₂₂N₂

(1R,2R)-1,2-Diphenyl-2-(pyrrolidin-1-yl)ethan-1-amine chemical structure, C18H22N2, CAS 865981-02-8

(1R,2R)-1,2-Diphenyl-2-(pyrrolidin-1-yl)ethan-1-amine

CAS 865981-02-8C₁₈H₂₂N₂

1-[2-(2-Fluorophenyl)-1-phenylethyl]pyrrolidine chemical structure, C18H20FN, CAS 920959-09-7

1-[2-(2-Fluorophenyl)-1-phenylethyl]pyrrolidine

CAS 920959-09-7C₁₈H₂₀FN

1-[(1R)-2-(4-Bromophenyl)-1-phenylethyl]pyrrolidine chemical structure, C18H20BrN, CAS 912339-50-5

1-[(1R)-2-(4-Bromophenyl)-1-phenylethyl]pyrrolidine

CAS 912339-50-5C₁₈H₂₀BrN

Fluorolintane chemical structure, C18H20FN, CAS 2149042-90-8

CAS 2149042-90-8C₁₈H₂₀FN